在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CANT1 Antibody

  • 中文名稱:
    CANT1兔多克隆抗體
  • 貨號:
    CSB-PA004484GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    CANT1
  • 別名:
    Apyrase antibody; Apyrase homolog antibody; Ca2+ dependent endoplasmic reticulum nucleoside diphosphatase antibody; Calcium activated nucleotidase 1 antibody; CANT 1 antibody; CANT1 antibody; CANT1_HUMAN antibody; Putative MAPK activating protein PM09 antibody; Putative MAPK-activating protein PM09 antibody; Putative NF kappa B activating protein 107 antibody; Putative NF-kappa-B-activating protein 107 antibody; SCAN 1 antibody; SCAN-1 antibody; SHAPY antibody; Soluble Ca activated nucleotidase isozyme 1 antibody; Soluble calcium activated nucleotidase 1 antibody; Soluble calcium activated nucleotidase SCAN 1 antibody; Soluble calcium-activated nucleotidase 1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human CANT1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > UTP > GTP. Has very low activity towards ADP and even lower activity towards ATP. Does not hydrolyze AMP and GMP. Involved in proteoglycan synthesis.
  • 基因功能參考文獻:
    1. CANT1 long non-coding RNA triggers efficient therapeutic efficacy by correcting aberrant long non-coding cascade in malignant uveal melanoma. PMID: 28330694
    2. The Multiple Epiphyseal Dysplasia (MED)phenotype is thus allelic to the more severe Desbuquois dysplasia phenotype and the results identify CANT1 as a second locus for recessively inherited MED PMID: 28742282
    3. a novel mutation of CANT1, c.467C>T (p.Ser156Phe) in 3 Indian patients with Desbuquois dysplasia, Kim type from 2 families PMID: 25486376
    4. Data studied proteoglycan synthesis in CANT1 mutated patient fibroblasts, and found significant reduced GAG synthesis in presence of beta-D-xyloside, suggesting that CANT1 plays a role in proteoglycan metabolism. PMID: 22539336
    5. Novel mutations in the CANT1 gene are reported in three cases of Desbuquois dysplasia type I and fetal hydrops. PMID: 21654728
    6. estimated the age of the founder mutation as approximately 1420 years PMID: 21412251
    7. CANT1 is commonly overexpressed in the vast majority of primary prostate carcinomas and in the precursor lesion PIN and may represent a novel prognostic biomarker PMID: 21435463
    8. The clinical-radiographic spectrum produced by CANT1 mutations must be extended to include Desbuquois dysplasia type 2 and Kim variant. PMID: 21037275
    9. Cloning, expression, and characterization of this calcium-acdtivated enzyme, a human enzyme belonging to a new family of extracellular nucleotidases. PMID: 12234496
    10. This soluble apyrase is a calcium-binding protein, as evident from saturable Ca2+-dependent changes in intrinsic tryptophan fluorescence, UV difference absorption spectra, and Ca2+-triggered transition from enzymatically inactive form to active enzyme. PMID: 12600208
    11. The importance of the dimeric state for enzymatic activity and biological function in this nucleotidase by mutating isoleucine 170, is investigated. PMID: 18067325
    12. human soluble calcium-activated nucleotidase inhibits coagulation in vitro and thrombosis in vivo PMID: 18222531
    13. The two novel ETV4 fusion partners possess as predominant common characteristics androgen-induction and prostate-specific expression. PMID: 18451133
    14. Mutations in CANT1 in Desbuquois dysplasia are identified. PMID: 19853239

    顯示更多

    收起更多

  • 相關疾?。?/div>
    Desbuquois dysplasia 1 (DBQD1); Epiphyseal dysplasia, multiple, 7 (EDM7)
  • 亞細胞定位:
    Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Cell membrane. Note=Processed form: Secreted.
  • 蛋白家族:
    Apyrase family
  • 組織特異性:
    Widely expressed.
  • 數據庫鏈接:

    HGNC: 19721

    OMIM: 251450

    KEGG: hsa:124583

    STRING: 9606.ENSP00000307674

    UniGene: Hs.8859



主站蜘蛛池模板: 国产精品多人p群无码| 无码av中文一区二区三区桃花岛| 久久人人爽人人爽人人片av高请| 欧美丰满少妇xxxx性| 直接观看黄网站免费视频 | 精品人妻无码区在线视频| 人妻少妇乱子伦无码专区| 无码中文人妻在线一区| 手机看片精品国产福利| 国产在线视频主播区| 成人试看120秒体验区| 18禁高潮出水呻吟娇喘蜜芽| 69精品人人人人| 少妇愉情理伦片丰满丰满午夜| 少妇人妻大乳在线视频不卡| 国产乱人伦av在线麻豆a| 亚洲精品久久久www小说 | 国产偷窥熟女精品视频大全| 欧美黑人巨大xxxxx| 成在线人免费视频一区二区| 国内高清久久久久久| 免费毛片手机在线播放| 亚洲五月色丁香婷婷婷| 国模gogo无码人体啪啪| 国产成人三级一区二区在线观看一| 天堂俺去俺来也www色官网| 丰满多毛的陰户视频| 777米奇色狠狠俺去啦奇米77| 国产高清自产拍av在线| 国产精品无码人妻一区二区在线| 无码尹人久久相蕉无码| 日本成熟少妇喷浆视频| 手机国产乱子伦精品视频| 四虎影视永久免费观看| 国产熟妇搡bbbb搡bbbb搡| 国内精品久久久久影视老司机| 无码三级av电影在线观看| 中文字幕日韩人妻无码| 国产亚洲精品久久久网站好莱 | 巨爆乳无码视频在线观看| 中年人妻丰满av无码久久不卡 |