在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CADM3 Antibody

  • 中文名稱:
    CADM3兔多克隆抗體
  • 貨號:
    CSB-PA195475
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA195475(CADM3 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA195475(CADM3 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    CADM3
  • 別名:
    BIgR antibody; Brain immunoglobulin receptor antibody; CADM 3 antibody; cadm3 antibody; CADM3_HUMAN antibody; Cell adhesion molecule 3 antibody; Dendritic cell nectin like protein 1 short isoform antibody; FLJ10698 antibody; IgSF4B antibody; Immunoglobulin superfamily member 4B antibody; Necl 1 antibody; Necl-1 antibody; NECL1 antibody; Nectin like 1 antibody; Nectin like protein 1 antibody; Nectin-like protein 1 antibody; Synaptic cell adhesion molecule 3 antibody; synCAM3 antibody; TSLC1 like 1 antibody; TSLC1 like protein 1 antibody; TSLC1-like protein 1 antibody; TSLL1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Fusion protein of Human CADM3
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Involved in the cell-cell adhesion. Has both calcium-independent homophilic cell-cell adhesion activity and calcium-independent heterophilic cell-cell adhesion activity with IGSF4, NECTIN1 and NECTIN3. Interaction with EPB41L1 may regulate structure or function of cell-cell junctions.
  • 基因功能參考文獻:
    1. CADM3 expression was increased in retinoblastoma tissues and cells. miR-140-5p inhibited CADM3 expression possibly by targeting the 3'-UTR. PMID: 29808799
    2. Nectin-based cell-cell adhesion was formed at the apical side of the junctional adhesion molecule (JAM)-based cell-cell adhesion; cadherin and claudin were recruited to the nectin-3 and JAM-based cell-cell adhesion sites to form AJ- and TJ-like domains. PMID: 24112238
    3. NECL1 can inhibit the migration and invasion of glioma cells and induce differentiation. PMID: 20078932
    4. Findings clearly reveal the structural basis for the cis-dimerization of nectins through the first Ig-like domains. PMID: 21325282
    5. A link might exist between NECL1 and the extracellular matrix protein OPN in inhibiting the migration and invasion of U251 glioma ce PMID: 20598232
    6. NECL1 may inhibit the proliferation of T98G cells by inducing its apoptosis. PMID: 18686605
    7. Nec- 1 suppress the growth and tumorigenic ability of colon cancer cells. PMID: 19565570
    8. Necl-1 is a neural-tissue-specific Ca2+-independent immunoglobulin-like cell-cell adhesion molecule which potentially has membrane-associated guanylate kinase subfamily member-binding activity and localizes at the non-junctional cell-cell contact sites PMID: 15741237
    9. crystallographic analysis of human Nectin-like molecule-1/Syncam3/Tsll1/Igsf4b, a neural tissue-specific immunoglobulin-like cell-cell adhesion molecule PMID: 16467305
    10. human NECL1 is an N-linked glycoprotein with a single glycosylation site at position N290KS PMID: 18420026
    11. Expression of entry receptors nectin-1 and HVEM prevent entry of HSV-1 into human conjunctival epithelium. PMID: 18502984
    12. suggests that NECL1 may act as a tumor suppressor in glioma and loss of it in glioma may be caused by histone deacetylation PMID: 19062177

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Single-pass type I membrane protein. Cell junction.
  • 蛋白家族:
    Nectin family
  • 組織特異性:
    Isoform 1 is expressed mainly in adult and fetal brain. Isoform 2 is highly expressed in adult brain and weakly expressed in placenta. In brain, Isoform 2 is highly expressed in cerebellum.
  • 數據庫鏈接:

    HGNC: 17601

    OMIM: 609743

    KEGG: hsa:57863

    UniGene: Hs.365689



主站蜘蛛池模板: 国产男女猛烈无遮挡a片漫画| 色窝窝免费播放视频在线| 一道久在线无码加勒比| 婷婷丁香五月中文字幕| 中文字幕丰满孑伦无码精品| 日本亚洲vr欧美不卡高清专区| 无码综合天天久久综合网色吧影院 | 麻豆专媒体一区二区| 日韩吃奶摸下aa片免费观看| 无码人妻丰满熟妇区五十路| 久久精品国产精品久久久| 欧美乱人伦视频在线| 欧美午夜刺激影院| 女人爽到高潮免费视频大全| 99久久精品国产成人综合 | 最新亚洲春色av无码专区| 日韩无套内射视频6| 国产精品视频色拍在线视频| 在线观看肉片av网站免费| 欧美丰满老熟妇xxxxx性| 人妻三级日本香港三级极| 欧美性大战xxxxx久久久√| 蜜臀精品无码av在线播放| 亚洲乱码中文字幕久久孕妇黑人| 亚洲色老汉av无码专区最| 和黑人邻居中文字幕在线| 无码国产69精品久久久久孕妇| 人妻少妇邻居少妇好多水在线| 久久久精品456亚洲影院| 99久久精品费精品国产一区二区| 亚洲日韩中文无码久久| 狠人干练合综合网| 色婷婷亚洲一区二区综合| 国产精品久线在线观看| 亚洲欧美日韩成人综合网| 国产精品无需播放器在线观看| 国精产品999国精产品官网| 久久96国产精品久久久| 日韩免费人妻av无码专区蜜桃| 亚洲一区二区三区| 18禁裸体动漫美女无遮挡网站 |