在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CADM3 Antibody

  • 中文名稱:
    CADM3兔多克隆抗體
  • 貨號:
    CSB-PA195475
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA195475(CADM3 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA195475(CADM3 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    CADM3
  • 別名:
    BIgR antibody; Brain immunoglobulin receptor antibody; CADM 3 antibody; cadm3 antibody; CADM3_HUMAN antibody; Cell adhesion molecule 3 antibody; Dendritic cell nectin like protein 1 short isoform antibody; FLJ10698 antibody; IgSF4B antibody; Immunoglobulin superfamily member 4B antibody; Necl 1 antibody; Necl-1 antibody; NECL1 antibody; Nectin like 1 antibody; Nectin like protein 1 antibody; Nectin-like protein 1 antibody; Synaptic cell adhesion molecule 3 antibody; synCAM3 antibody; TSLC1 like 1 antibody; TSLC1 like protein 1 antibody; TSLC1-like protein 1 antibody; TSLL1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Fusion protein of Human CADM3
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Involved in the cell-cell adhesion. Has both calcium-independent homophilic cell-cell adhesion activity and calcium-independent heterophilic cell-cell adhesion activity with IGSF4, NECTIN1 and NECTIN3. Interaction with EPB41L1 may regulate structure or function of cell-cell junctions.
  • 基因功能參考文獻:
    1. CADM3 expression was increased in retinoblastoma tissues and cells. miR-140-5p inhibited CADM3 expression possibly by targeting the 3'-UTR. PMID: 29808799
    2. Nectin-based cell-cell adhesion was formed at the apical side of the junctional adhesion molecule (JAM)-based cell-cell adhesion; cadherin and claudin were recruited to the nectin-3 and JAM-based cell-cell adhesion sites to form AJ- and TJ-like domains. PMID: 24112238
    3. NECL1 can inhibit the migration and invasion of glioma cells and induce differentiation. PMID: 20078932
    4. Findings clearly reveal the structural basis for the cis-dimerization of nectins through the first Ig-like domains. PMID: 21325282
    5. A link might exist between NECL1 and the extracellular matrix protein OPN in inhibiting the migration and invasion of U251 glioma ce PMID: 20598232
    6. NECL1 may inhibit the proliferation of T98G cells by inducing its apoptosis. PMID: 18686605
    7. Nec- 1 suppress the growth and tumorigenic ability of colon cancer cells. PMID: 19565570
    8. Necl-1 is a neural-tissue-specific Ca2+-independent immunoglobulin-like cell-cell adhesion molecule which potentially has membrane-associated guanylate kinase subfamily member-binding activity and localizes at the non-junctional cell-cell contact sites PMID: 15741237
    9. crystallographic analysis of human Nectin-like molecule-1/Syncam3/Tsll1/Igsf4b, a neural tissue-specific immunoglobulin-like cell-cell adhesion molecule PMID: 16467305
    10. human NECL1 is an N-linked glycoprotein with a single glycosylation site at position N290KS PMID: 18420026
    11. Expression of entry receptors nectin-1 and HVEM prevent entry of HSV-1 into human conjunctival epithelium. PMID: 18502984
    12. suggests that NECL1 may act as a tumor suppressor in glioma and loss of it in glioma may be caused by histone deacetylation PMID: 19062177

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Single-pass type I membrane protein. Cell junction.
  • 蛋白家族:
    Nectin family
  • 組織特異性:
    Isoform 1 is expressed mainly in adult and fetal brain. Isoform 2 is highly expressed in adult brain and weakly expressed in placenta. In brain, Isoform 2 is highly expressed in cerebellum.
  • 數據庫鏈接:

    HGNC: 17601

    OMIM: 609743

    KEGG: hsa:57863

    UniGene: Hs.365689



主站蜘蛛池模板: 亚洲色18禁成人网站www| 午夜福利精品导航凹凸| 性欧美老妇另类xxxx| 少妇扒开腿让我爽了一夜| 日本免费一区二区三区四区五六区| 五十路亲子中出在线观看| 人妻avav中文系列久久| 亚洲国产成人精品无码区二本| 久久久久久好爽爽久久| 无码精品国产va在线观看| 人人妻人人澡av| 中字幕人妻一区二区三区| 欧美黑人xxxx又粗又长| 午夜亚洲影院在线观看| 久久97超碰色中文字幕总站| 人人妻人人澡人人爽| 国产绳艺sm调教室论坛| 国产av成人精品播放| 国产乱人伦av在线a最新| 日本丶国产丶欧美色综合| 狠狠躁夜夜躁人人爽天天5 | 一区二区国产高清视频在线| 中文天堂国产最新| 美女张开腿黄网站免费下载| 亚洲免费网站观看视频| 亚洲天天做日日做天天欢毛片| 人与性动交aaaabbbb| 国产影片中文字幕| 午夜福利18以下勿进免费| 在线观看无码av网址| 国产二级一片内射视频插放| 少妇与黑人一二三区无码| 亚洲在av极品无码天堂手机版| 欧美乱人伦视频在线| 女人喷潮完整视频| 久久国产劲爆∧v内射-百度| av无码一区二区二三区1区6区| 新香蕉少妇视频网站| 97伦伦午夜电影理伦片| 伊人情人色综合网站| 小小拗女性bbwxxxx国产|