在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CA12 Antibody, HRP conjugated

  • 中文名稱:
    CA12兔多克隆抗體, HRP偶聯(lián)
  • 貨號(hào):
    CSB-PA004367YB01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) CA12 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    CA 12 antibody; CA XII antibody; CA-XII antibody; CA12 antibody; CAH12_HUMAN antibody; Carbonate dehydratase XII antibody; Carbonic anhydrase 12 antibody; Carbonic anhydrase XII antibody; Carbonic dehydratase antibody; CAXII antibody; FLJ20151 antibody; HsT18816 antibody; T18816 antibody; Tumor antigen HOM RCC 3.1.3 antibody; Tumor antigen HOM-RCC-3.1.3 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Carbonic anhydrase 12 protein (25-301AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Reversible hydration of carbon dioxide.
  • 基因功能參考文獻(xiàn):
    1. Our findings indicate that loss of CA XII function should be considered in individuals without CFTR mutations who exhibit CF-like features in the sweat gland and lung. PMID: 26911677
    2. The expression of HIF-1alpha, but not HIF-2alpha, decreased in degenerated disc samples and was positively correlated with carbonic anhydrase 12 expression. PMID: 26901836
    3. mutation CA12(E143K) causes mouth dryness disease due to aberrant CA12 glycosylation. PMID: 26486891
    4. Suggest CAXII as a new secondary marker of the multidrug resistance phenotype that influences Pgp activity directly. PMID: 25686827
    5. an upregulation of CAXII in human T-cell acute lymphoblastic leukemia samples supporting the case that CAXII may represent a new therapeutic target for T-ALL/LL. PMID: 23348702
    6. Serum CAXII levels were significantly higher in lung cancer patients than in healthy controls, providing evidence that CAXII may be a novel sero-diagnostic marker for lung cancer. PMID: 22439015
    7. The expression of CA XII in oral squamous cell carcinoma (OSCC) samples can predict the progression of OSCC and survival of OSCC patients. PMID: 22172588
    8. The development of acidosis with topiramate and zonisamide is not determined by drug dose or by treatment duration, but may be influenced by polymorphisms in the gene for CA type XII. PMID: 21278619
    9. Data show that genes overexpressed in breast carcinoma including TFF1, TFF3, FOXA1 and CA12.Data show that genes overexpressed in breast carcinoma including TFF1, TFF3, FOXA1 and CA12. PMID: 20132413
    10. Study identified the association of a Glu143Lys mutation in carbonic anhydrase 12 (CA12) with the disease. PMID: 21184099
    11. we demonstrate that the hyperchlohidrosis phenotype is due to a homozygous mutation in CA12, encoding carbonic anhydrase XII. PMID: 21035102
    12. CA12 may be used as a novel prognostic marker in combination with histologic grade of invasive cervical cancer. PMID: 21040567
    13. Carbonic anhydrase XII may affect the capability of invasion and migration of MDA-MB-231 cells, which may be mediated through the p38 MAPK pathway. PMID: 20434230
    14. Suggest that CA XII should be considered a potential prognostic and therapeutic target in medulloblastomas and supratentorial primitive neuroectodermal tumours. PMID: 20398423
    15. Differential modulation of the active site environment of human carbonic anhydrase XII by cationic quantum dots and polylysine. PMID: 20215053
    16. The non-pigmented ciliary epithelial cells from glaucoma eyes expressed higher levels of CAXII, which may be a targeted gene in glaucoma. PMID: 12676895
    17. CA XII showed no or weak immunoreaction in the normal gastric mucosa and was slightly increased in gastric tumors. PMID: 12854129
    18. The interplay between the functional von Hippel-Lindau tumor suppressor and CA IX/CA XII in colorectal tumors seems rather PMID: 15849821
    19. CA12 mRNA expression was detected in 88.1% of cervical cancers. PMID: 16416108
    20. CA XII is commonly expressed in diffuse astrocytomas and that it might be used as a biomarker of poor prognosis. PMID: 18322268
    21. Carbonic anhydrase (CA) IX (and possibly also CA XII) participates in pH regulation, which is important for survival of hypoxic cancer cells. Both enzymes are therefore promising targetable therapeutic molecules. [Review] PMID: 18336315
    22. Crucial role of ER in the regulation of the CA12 gene. PMID: 18451179
    23. In embryonic and early fetal tissues; there is no evidence of co-localization of CAIX and CAXII; CAIX and CAXII expression is closely related to cell origin and secretory activity involving proton transport, respectively. PMID: 19291313

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Hyperchlorhidrosis, isolated (HCHLH)
  • 亞細(xì)胞定位:
    Membrane; Single-pass type I membrane protein. Cell membrane.
  • 蛋白家族:
    Alpha-carbonic anhydrase family
  • 組織特異性:
    Highly expressed in colon, kidney, prostate, intestine and activated lymphocytes. Expressed at much higher levels in the renal cell cancers than in surrounding normal kidney tissue. Moderately expressed in pancreas, ovary and testis. Expressed in sweat gl
  • 數(shù)據(jù)庫鏈接:

    HGNC: 1371

    OMIM: 143860

    KEGG: hsa:771

    STRING: 9606.ENSP00000178638

    UniGene: Hs.210995



主站蜘蛛池模板: 五月丁香啪啪| 2020精品国产视| 国产在线精品欧美日韩电影| 国内嫩模私拍精品视频| 一区二区三区内射美女毛片| 一边添奶一边添p好爽视频| 亚洲精品国产精华液有哪些| 麻豆人妻无码性色av专区 | 国产日产欧产精品精品免费| 国产肉丝袜在线观看| 国产成人女人在线观看| 一区二区三区在线 | 欧| 国产揉捏爆乳巨胸挤奶视频| 亚洲人成手机电影网站| 夜夜高潮夜夜爽夜夜爱爱一区 | 十八禁裸体www网站免费观看| 少妇被躁爽到高潮| 国产精品亚洲专区无码老司国| 国产亚洲精品久久77777| 国产欧美日韩综合精品一区二区| 都市激情 在线 亚洲 国产| 国产成人精品久久久久精品日日| 亚洲国产精品一区二区制服| 精品国产青草久久久久福利| 天堂在/线资源中文在线| 亚洲成本人无码薄码区| 免费看成人毛片无码视频| 亚洲中文字幕无码中字| 女人被做到高潮免费视频| 麻豆人妻无码性色av专区| 中文字幕被公侵犯的漂亮人妻| 国产精品久久..4399| 亚洲国产一区二区三区在观看| av无码久久久久不卡网站下载| 青青青国产精品一区二区| 精品久久久久久久久久久国产字幕| 国产强奷在线播放免费 | 亚洲色精品aⅴ一区区三区| 国产成人vr精品a视频| 强伦姧人妻免费无码电影| 99er热精品视频|