C1D Antibody
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中文名稱:C1D兔多克隆抗體
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貨號:CSB-PA003488GA01HU
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規格:¥3,900
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其他:
產品詳情
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Uniprot No.:
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基因名:C1D
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別名:1110036E10Rik antibody; AI875855 antibody; C1D antibody; C1D DNA binding protein antibody; C1D_HUMAN antibody; hC1D antibody; LRP1 antibody; MGC12261 antibody; MGC14659 antibody; MGC188504 antibody; Nuclear DNA binding protein antibody; Nuclear nucleic acid binding protein C1D antibody; Nuclear nucleic acid-binding protein C1D antibody; rCG23324 antibody; RGD1560600 antibody; Small unique nuclear receptor corepressor antibody; SUNCOR antibody
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宿主:Rabbit
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反應種屬:Human,Mouse,Rat
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免疫原:Human C1D
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免疫原種屬:Homo sapiens (Human)
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抗體亞型:IgG
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純化方式:Antigen Affinity Purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式:Liquid
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應用范圍:ELISA,IHC
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Protocols:
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儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途:For Research Use Only. Not for use in diagnostic or therapeutic procedures.
相關產品
靶點詳情
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功能:Plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA; this function may include MPHOSPH6. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB.
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基因功能參考文獻:
- C1D is associated with the DNA repair complex and may promote repair of ultraviolet irradiation-induced DNA damage. PMID: 20530579
- Results are consistent with a role for the exosome-associated protein C1D in the recruitment of the exosome to pre-rRNA to mediate the 3' end processing of the 5.8S rRNA. PMID: 17412707
- Anti-C1D autoantibodies were observed in patients with polymyositis-scleroderma overlap syndrome. PMID: 17599775
- TRAX enhances the DNA binding capacity of Translin, that binds to recombination regions in some malignancies. C1D interacts with TRAX following g-irradiation and prevents formation of TRAX/Translin complex, thereby inhibits any unwanted recombination. PMID: 11801738
- The C1D protein interacts with the catalytic subunit of DNA-PK and is a very effective substrate for DNA-PK in vitro. Moreover, C1D directs the activation of DNA-PK in a manner that does not require DNA termini, suggesting a role for C1D in DNA repair. PMID: 9679063
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亞細胞定位:Nucleus. Cytoplasm. Nucleus, nucleolus.
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蛋白家族:C1D family
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組織特異性:Ubiquitous. Expressed at very high levels in the hippocampus, medulla oblongata, mammary gland, thyroid and salivary gland. Expressed at high levels in the fetal; lung, liver and kidney. Expressed at low levels in skeletal muscle, appendix, heart, lung an
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數據庫鏈接:
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