在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. BRS3 Antibody

BRS3 Antibody

  • 中文名稱：
    BRS3兔多克隆抗體
  • 貨號：
    CSB-PA050181
  • 規(guī)格：
    ￥1090
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    BRS3; Bombesin receptor subtype-3; BRS-3
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human BRS-3.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, IHC, IF, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:10000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Role in sperm cell division, maturation, or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
  • 基因功能參考文獻(xiàn)：
    1. These results suggest that human BRS-3, similar to GRPR/NMBR, is frequently ectopically-expressed by lung-cancer cells in which, it is functional, affecting cell signaling/growth. PMID: 29410320
    2. mammalian homologue of CCHa2-R, Bombesin receptor subtype-3 (Brs3), is an orphan receptor that is expressed in the islet beta-cells PMID: 26020940
    3. High BRS3 expression is associated with liver metastases of pancreas neuroendocrine tumors. PMID: 25241033
    4. The role of the human BRS-3 receptor in glucose homeostasis. PMID: 24220502
    5. Data show that gastrin-releasing peptide receptor/bombesin receptor subtype-3 positive cells and protein expression in tumors decreased by treatment with RC-3095 or gemcitabine alone or greater in combination. PMID: 24326363
    6. BRS-3 plays an important role in glucose metabolism. PMID: 23291341
    7. BRS-3 agonist-dependent signaling mediates CREB phosphorylation and transactivation through protein kinase (PK)A, (PK)C, and mitogen-activated protein/extracellular regulated kinase kinase (MEK)-1 pathways. PMID: 22127929
    8. These results identify a potential role for BRS-3 in islet physiology, with agonism directly promoting glucose-stimulated insulin secretion PMID: 21878513
    9. results indicate that the sequence variation in the E3 loop is responsible for the species difference between rat and human BRS-3, and multiple residues in the E3 loop are involved in interactions with the agonist dY-bombesin PMID: 12102638
    10. Study found that the BRS-3 agonist stimulated adhesion of NCI-N417 cells in laminin-coated culture wells suggesting that BRS-3 may be involved in invasion and metastasis of certain cancer cells PMID: 16979789
    11. Data suggest that activator protein 2alpha and peroxisome-proliferator-activated receptor alpha may be especially involved in the ozone-inducible up-regulation mechanism of bombesin receptor subtype 3 expression. PMID: 17355223
    12. The secretion of TGF-beta1 increased and the synthesis of PGE2 decreased from BRS-3-activated BEC, which were correlated with the proliferation and collagen synthesis of HLF. PMID: 17714959

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 組織特異性：
    In germ cells in testis. Lung carcinoma cells.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 1113

    OMIM: 300107

    KEGG: hsa:680

    STRING: 9606.ENSP00000359682

    UniGene: Hs.121484



主站蜘蛛池模板： 久九九久视频精品免费| 亚洲国内精品自在线影院| 少妇内射兰兰久久| 日日橹狠狠爱欧美视频| 亚洲欧美国产va在线播放| 蜜桃视频在线观看免费视频网站www| 热re99久久精品国产66热| 四虎国产精品永久免费网址| 日本亚洲欧洲另类图片| 国产成人理论无码电影网| 欧美日韩在线视频一区| 精品久久久噜噜噜久久久| 国内久久婷婷五月综合色| 亚洲午夜精品a片一区二区app| 激情欧美成人久久综合| 丁香色婷婷国产精品视频| 精品麻豆丝袜高跟鞋av| 99大香伊乱码一区二区| 四虎成人精品在永久免费| 亚洲日韩激情无码一区| 天天摸天天做天天爽天天弄| 免费看男女做羞羞的事网站| 一本一本久久aa综合精品| 好男人社区神马在线观看www| 免费看国产精品3a黄的视频| 亚洲国产精品无码中文lv| 亚洲人成电影网站色www| 久久久久久国产精品无码超碰 | 高清乱码一区二区三区| 亚洲色无码中文字幕yy51999| 欧美 丝袜 自拍 制服 另类| 亚洲综合久久无码色噜噜赖水| 欧美人与动性xxxxx交性| 少妇无码吹潮| 亚洲色无码国产精品网站可下载 | 国产三级在线观看播放视频| 高潮毛片无遮挡高清免费| 3p人妻少妇对白精彩视频| 最新精品国偷自产在线老年人| 热99re久久精品| 国产亚洲成av人片在线观看 |