在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. BRD8 Antibody

BRD8 Antibody

  • 中文名稱：
    BRD8兔多克隆抗體
  • 貨號：
    CSB-PA002805GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    BRD8 antibody; SMAP antibody; SMAP2 antibody; Bromodomain-containing protein 8 antibody; Skeletal muscle abundant protein antibody; Skeletal muscle abundant protein 2 antibody; Thyroid hormone receptor coactivating protein of 120 kDa antibody; TrCP120 antibody; p120 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human BRD8
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    May act as a coactivator during transcriptional activation by hormone-activated nuclear receptors (NR). Isoform 2 stimulates transcriptional activation by AR/DHTR, ESR1/NR3A1, RXRA/NR2B1 and THRB/ERBA2. At least isoform 1 and isoform 2 are components of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AZ1 from the nucleosome.
  • 基因功能參考文獻：
    1. miR-185 can attenuate androgen receptor function indirectly by suppressing BRD8 ISO2 PMID: 26940039
    2. incorporation of the histone variant H2A.Z at the promoter regions of PPARgamma target genes by p400/Brd8 is essential to allow fat cell differentiation PMID: 23064015
    3. SMAP gene family constitutes an important ArfGAP subfamily, with each SMAP member exerting both common and distinct functions in vesicle trafficking. PMID: 16571680
    4. BRD8 expression is associated with tumor progression toward advanced stages PMID: 19787264
  • 亞細胞定位：
    Nucleus.
  • 組織特異性：
    Expressed in adipose tissue, brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 19874

    OMIM: 602848

    KEGG: hsa:10902

    STRING: 9606.ENSP00000254900

    UniGene: Hs.519337



主站蜘蛛池模板： 欧美大黑帍在线播放| 亚洲午夜成人片| 一个人在线观看免费中文www| 忘忧草社区中文字幕www| 久久视频在线视频精品| 一边吃奶一边添p好爽高清视频| 久久婷婷五月综合97色| 一日本道a高清免费播放| 日韩人妻无码一区二区三区99| 国产人妻大战黑人第1集| 亚洲精品少妇一区二区| 久久国产中文娱乐网| 欧美猛少妇色xxxxx猛叫 | 99久久精品国产一区二区蜜芽| 欧美色欧美亚洲另类二区| 国产成人啪精品视频免费视频| 久久综合九色综合国产| 国产精品白丝喷水在线观看| 无码国产欧美一区二区三区不卡| 久久99精品久久久久久2021| 国产亚洲精品美女久久久| 精品久久人人妻人人做精品| 伊人色综合久久天天人守人婷| 亚洲国产成人精品无码区在线观看| 一区二区在线 | 欧洲| 波多野结衣绝顶大高潮| 99热精品国自产拍天天拍| 国产精品女视频一区二区| 色偷偷888欧美精品久久久| 猫咪www免费人成网站无码| 三级无码在钱av无码在钱| 亚洲爆乳少妇无码激情| av无码久久久久久不卡网站| 野花在线无码视频在线播放| 天堂а√在线地址8| 国产极品美女高潮无套在线观看| 日韩精品无码中文字幕一区二区| 亚洲欧美日韩国产精品一区| 狠狠躁夜夜躁av网站中文字幕| 亚洲欧美日韩国产综合v| 特级毛片全部免费播放|