在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. BRD8 Antibody

BRD8 Antibody

  • 中文名稱：
    BRD8兔多克隆抗體
  • 貨號：
    CSB-PA002805GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    BRD8 antibody; SMAP antibody; SMAP2 antibody; Bromodomain-containing protein 8 antibody; Skeletal muscle abundant protein antibody; Skeletal muscle abundant protein 2 antibody; Thyroid hormone receptor coactivating protein of 120 kDa antibody; TrCP120 antibody; p120 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human BRD8
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    May act as a coactivator during transcriptional activation by hormone-activated nuclear receptors (NR). Isoform 2 stimulates transcriptional activation by AR/DHTR, ESR1/NR3A1, RXRA/NR2B1 and THRB/ERBA2. At least isoform 1 and isoform 2 are components of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AZ1 from the nucleosome.
  • 基因功能參考文獻：
    1. miR-185 can attenuate androgen receptor function indirectly by suppressing BRD8 ISO2 PMID: 26940039
    2. incorporation of the histone variant H2A.Z at the promoter regions of PPARgamma target genes by p400/Brd8 is essential to allow fat cell differentiation PMID: 23064015
    3. SMAP gene family constitutes an important ArfGAP subfamily, with each SMAP member exerting both common and distinct functions in vesicle trafficking. PMID: 16571680
    4. BRD8 expression is associated with tumor progression toward advanced stages PMID: 19787264
  • 亞細胞定位：
    Nucleus.
  • 組織特異性：
    Expressed in adipose tissue, brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 19874

    OMIM: 602848

    KEGG: hsa:10902

    STRING: 9606.ENSP00000254900

    UniGene: Hs.519337



主站蜘蛛池模板： 少妇一边呻吟一边说使劲| 亚洲第一aaaaa片| 99国产欧美久久久精品蜜芽| 精品亚洲国产成人av在线时间短的 | 永久免费看啪啪的网站| 天堂岛国av无码免费无禁网站| 精品日产一卡2卡三卡4卡在线| 乱女伦露脸对白在线播放| 亚洲不卡av不卡一区二区| 亚洲精品国产美女久久久| 在线成人爽a毛片免费软件| 国产a在亚洲线播放| 婷婷四房综合激情五月在线| 美女mm131午夜福利在线| 亚洲中文字幕无码久久2018| 94久久国产乱子伦精品免费| 久久亚洲美女精品国产精品| 印度妓女野外xxww| 精品国产一区二区三区久久久狼| 国产色视频一区二区三区| 无码国产成人午夜视频在线播放| 无码一卡二卡三卡四卡| 在线亚洲综合欧美网站首页| 2021亚洲国产成a在线| 风间由美性色一区二区三区| 无码av天天av天天爽| 欧美做受视频播放| 国产无吗一区二区三区在线欢| 躁躁躁日日躁| 婷婷五月俺也去人妻| 在线亚洲97se亚洲综合在线| 国产卡一卡二卡三无线乱码新区| 亚洲欧美日本国产专区一区| 国产午夜亚洲精品国产成人| 中字幕视频在线永久在线观看免费| 夜夜躁狠狠躁2021| 成+人+网+站+免费观看| 少妇愉情理伦片bd| 亚洲精品成人无限看| 五月综合色婷婷在线观看| 日韩少妇人妻vs中文字幕|