在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

BCAS2 Antibody

  • 中文名稱:
    BCAS2兔多克隆抗體
  • 貨號:
    CSB-PA000980
  • 規格:
    ¥1090
  • 圖片:
    • Western Blot analysis of COS7 cells using BCAS2 Polyclonal Antibody
    • Western Blot analysis of K562 NIH-3T3 cells using BCAS2 Polyclonal Antibody
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    BCAS2
  • 別名:
    bcas2 antibody; Breast carcinoma amplified sequence 2 antibody; Breast carcinoma-amplified sequence 2 antibody; DAM 1 antibody; DAM-1 antibody; DAM1 antibody; DNA amplified in mammary carcinoma 1 protein antibody; MGC7712 antibody; Pre mRNA splicing factor SPF27 antibody; Pre-mRNA-splicing factor spf27 antibody; Snt309 antibody; SPF27 antibody; SPF27_HUMAN antibody; Spliceosome associated protein amplified in breast cancer antibody; Spliceosome associated protein SPF 27 antibody; Spliceosome-associated protein SPF 27 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat,Monkey
  • 免疫原:
    Synthesized peptide derived from the C-terminal region of Human BCAS2.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:5000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Required for pre-mRNA splicing as component of the activated spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).
  • 基因功能參考文獻:
    1. Study showed that CDK4 and BCAS2 may be target genes of miR-486 and levels of CDK4 and BCAS2 were both significantly higher in the esophageal cancer tissues and cell lines than levels in the normal tissues and cells. PMID: 29115564
    2. Chromosomal breakpoints involved the BCAS2 gene in 1q31 is associated with Diffuse Large B-Cell Lymphomas. PMID: 27356265
    3. BCAS2 interacts with HSF4 and negatively regulates its protein stability via ubiquitination. PMID: 26319152
    4. These results demonstrate that Aurora B inhibits both direct interaction with the microtubule and oligomerization of the Dam1 complex to drive error correction during mitosis. PMID: 26560693
    5. BCAS2 is a novel androgen receptor-interacting protein. PMID: 25461807
    6. ERRbeta signalling leads to BCAS2-mediated blockage of the G1/S transition and inhibition of the epithelial to mesenchymal transition through FST-mediated regulation of E-cadherin PMID: 24667650
    7. The BCAS2 gene was amplified in two of 60 primary breast cancer tissues, but not in other cancer cells, providing the first evidence of amplification within this region and indicating that BCAS2 gene codes for a nuclear protein. PMID: 12169396
    8. This study suggested that BCAS2 might play an important role in breast cancer development by increasing the estrogen receptor's function. PMID: 15694360
    9. BCAS2 directly interacts with p53 to reduce p53 transcriptional activity by mildly but consistently decreasing p53 protein in the absence of DNA damage. In the presence of DNA damage, BCAS2 prominently reduces p53 protein. PMID: 19903847

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Nucleus, nucleolus.
  • 蛋白家族:
    SPF27 family
  • 組織特異性:
    Ubiquitously expressed.
  • 數據庫鏈接:

    HGNC: 975

    OMIM: 605783

    KEGG: hsa:10286

    STRING: 9606.ENSP00000358554

    UniGene: Hs.22960



主站蜘蛛池模板: 亚洲精品无码中文久久字幕| 免费女人高潮流视频在线| 国产成人卡2卡3卡4乱码| 又硬又粗进去好爽免费| 欧美日韩国产精品| 99精品国产在热久久婷婷| av天堂永久资源网亚洲高清| 午夜视频在线观看免费完整版| av电影在线观看| 国产成人久久精品一区二区三区| 亚洲一区二区无码偷拍| 亚洲精品入口一区二区乱麻豆精品| 果冻传媒18禁免费视频| 精品国产sm最大网站| 黄在线看片免费人成视频| 亚洲国产精品成人精品无码区| 国产精品免费久久久久影院仙踪林| 亚洲日韩中文字幕一区| 亚洲伊人丝袜精品久久| 国产在线高清视频无码| 4399理论片午午伦夜理片| 成人精品视频一区二区三区| 国语自产拍在线视频中文| 亚洲成av人在线观看网站| 业余 自由 性别 成熟偷窥| 亚洲欧美日韩国产综合v| 亚洲成av人片在线观看一区二区三区 | av无码人妻波多野结衣| 疯狂三人交性欧美| 欧美日韩免费做爰大片人| 国产在线看片免费视频| 亚洲中文字幕aⅴ天堂| 色婷婷一区二区三区四区成人网| 国产亚洲日本精品成人专区| 一区二区三区四区在线不卡高清| 久久久亚洲精品一区二区三区浴池 | 国产av一二三无码影片| 一本大道久久久久精品嫩草| 亚洲伊人久久大香线蕉综合图片| 久久99精品久久久久久久不卡 | 午夜视频久久久久一区|