在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ATP5J Antibody

ATP5J Antibody

  • 中文名稱：
    ATP5J兔多克隆抗體
  • 貨號：
    CSB-PA002369GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    ATP synthase; H+ transporting; mitochondrial F0 complex; subunit F6 antibody; ATP synthase-coupling factor 6; mitochondrial antibody; ATP synthase-coupling factor 6; mitochondrial antibody; ATP5 antibody; ATP5A antibody; ATP5J antibody; ATP5J_HUMAN antibody; ATPase subunit F6 antibody; ATPM antibody; CF6 antibody; F6 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human ATP5J
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
  • 基因功能參考文獻：
    1. AKT2 and XIST expression was identified as a potential biomarker participating in the effect of ATP5J in colorectal cancer PMID: 29484395
    2. CF6-induced increase in apoptotic cells was blocked by immature or mature IF1, being accompanied by protein kinase B (PKB) phosphorylation. IF1 antagonizes the pro-apoptotic action of CF6 by relief of intracellular acidification and resultant phosphorylation of PKB. PMID: 26659871
    3. Over-expression of the ATP5J gene correlates with cell migration and 5-fluorouracil sensitivity in colorectal cancer. PMID: 24124598
    4. CF6 plays a crucial role in the development of insulin resistance and hypertension PMID: 22038518
    5. The phenotypic range of retinal, peripheral and central nervous system disease expression is characterized in a single family with NARP syndrome from the ATPase 6 m.8993T>C mtDNA point mutation. PMID: 20953793
    6. coupling factor 6 induces the development of systolic dysfunction and upregulation of nicotinamide adenine dinucleotide phosphate oxidase in the heart under the high-salt diet PMID: 20811295
    7. CF6 is a novel risk factor for ischemic heart disease in end-stage renal disease. Synergism of this peptide and asymmetric dimethylarginine might contribute to its occurrence presumably by inhibition of prostacyclin and nitric oxide production. PMID: 14633154
    8. Mutation analysis revealed the T9176C mutation in the mtATPase 6 gene (OMIM 516060) and the mutation load was above 90% in the patients with Leigh syndrome. PMID: 15709156
    9. Plasma CF6 elevated in patients with acute myocardial infarction. At 3 days, plasma CF6 correlated positively with plasma creatinine kinase peak value and correlated negatively with left ventricular ejection fraction. PMID: 15785006
    10. T8993G allele causes severe extrapyramidal dysfunction and Leigh disease but there is no correlation between the degree of enzyme deficiency and the severity of the phenotype. PMID: 16532470
    11. Increased CF6 may be responsible in part for decreased prostacyclin observed in coronary heart disease, in particular after PTCA and stent therapy. Potential risk factor for coronary heart disease. PMID: 17456993
    12. in vascular endothelial cells both CF6 (coupling factor 6) and Angiotensin II downregulate PECAM-1 (platelet/endothelial cell adhesion molecule) expression via activation of c-Src kinase PMID: 18243211
    13. Coupling factor 6 enhances Src-mediated responsiveness to angiotensin II in resistance arterioles and cells. PMID: 19106112

    顯示更多

    收起更多

  • 亞細胞定位：
    Mitochondrion. Mitochondrion inner membrane.
  • 蛋白家族：
    Eukaryotic ATPase subunit F6 family
  • 數據庫鏈接：

    HGNC: 847

    OMIM: 603152

    KEGG: hsa:522

    STRING: 9606.ENSP00000389649

    UniGene: Hs.246310



主站蜘蛛池模板： 老司机亚洲精品影院无码| 99久久人人爽亚洲精品美女| 国产精品18久久久久久vr| 插我舔内射18免费视频| 免费人成在线观看成人片| 一本清日本在线视频精品| 国产伦精品一区二区三区妓女| 天天色影网| 亚洲精品一品区二品区三区| 国产日韩欧美亚欧在线观看| 久久婷婷成人综合色综合| 无码一区二区三区| av中文无码乱人伦在线观看| 欧美35页视频在线观看| 国产成人精品久久| 亚洲精品一区二区三区婷婷月 | 色午夜一av男人的天堂| 无码专区—va亚洲v天堂麻豆| 国产精品va在线观看h| 黑人强辱丰满的人妻熟女| 无码av天堂一区二区三区| 国产成人精品永久免费视频| 久久精品一本到东京热| 中文字幕亚洲无线码在线一区| 激情偷乱人成视频在线观看| 永久免费无码网站在线观看个| 亚洲娇小与黑人巨大交| 久久人人爽人人爽人人片| 国产成人手机高清在线观看网站 | 精品国产一区二区三区四区阿崩| 国产精品卡1卡2卡三卡四| 国产成人啪精品视频免费网站软件| 三级无码在钱av无码在钱| 亚洲成av人的天堂在线观看| 国产成人综合色在线观看网站| 亚洲综合av一区二区三区不卡| 亚洲欧美成人精品香蕉网| 国产又黄又爽又猛免费视频播放| 一本之道av不卡精品| 国产成人精品日本亚洲语音| 中文精品久久久久人妻不卡|