在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ATP12A Antibody

ATP12A Antibody

  • 中文名稱：
    ATP12A兔多克隆抗體
  • 貨號：
    CSB-PA004747
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of rat stomach cells using ATP1AL1 Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    ATP12A antibody; ATP1AL1Potassium-transporting ATPase alpha chain 2 antibody; EC 7.2.2.19 antibody; Non-gastric H(+)/K(+) ATPase subunit alpha antibody; Proton pump antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human ATP1AL1.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    The catalytic subunit of a H(+)/K(+) ATPase and/or Na(+)/K(+) ATPase pump which transports K(+) ions in exchange for Na(+) and/or H(+) ions across the apical membrane of epithelial cells. Uses ATP as an energy source to pump K(+) ions into the cell while transporting Na(+) and/or H(+) ions to the extracellular compartment. Involved in the maintenance of electrolyte homeostasis through K(+) ion absorption in kidney and colon. In the airway epithelium, may play a primary role in mucus acidification regulating its viscosity and clearance.
  • 基因功能參考文獻：
    1. ATP12A knockdown or inhibition prevented the IL-13 dependent increase in airway surface liquid (ASL) viscosity but did not alter the ASL pH PMID: 29391451
    2. expressing human ATP12A in cystic fibrosis mouse airways acidified airway surface liquid, impaired defenses, and increased airway bacteria. PMID: 26823428
    3. Genetic association studies show that carriers of ATP12A rs10507337 C allele or CCTTC haplotype had better pattern of myocardial relaxation as compared to non-carriers. PMID: 25366262
    4. No significantly different expression levels could be detected in the various disease states compared to normal tissue. PMID: 22179016
    5. The presence of nongastric H-K-ATPase in rodent prostate apical membranes may indicate its involvement in potassium concentration regulation in secretions of these glands. PMID: 11880279
    6. Stimulation of protein kinase C pathway mediates endocytosis of human nongastric H+-K+-ATPase, ATP1AL1. PMID: 12110518
    7. Expressed in distal part of human colon and rectum, but also in proximal part of colon. Overexpressed in human colorectal adenocarcinomas adenocarcinomas. Astonishing levels of mRNA overexpression in carcinoma. PMID: 12230809
    8. Carboxy-terminus of HKalpha(2) facilitates proper folding of tHKalpha(2)/beta(1) complex allowing translocation of heterodimer to plasma membrane where potassium uptake occurs. Otherwise, alpha/beta complex is destined for degradation. PMID: 15086469
    9. non-gastric H(+)/K(+)ATPase is present in the microvillous plasma membrane of the transporting epithelia of the human placenta PMID: 15135233
    10. Inhibition of the ATP1AL1 isoenzyme of sodium potassium exchanging ATPase by 8-coumestrol is reported. PMID: 19487957
    11. Use of fold recognition methods enables a prediction that the C-terminal domain of the beta subunits of Na,K-ATPase and H,K-ATPase has an immunoglobulin-like fold, which resembles cell adhesion molecules. PMID: 19694409

    顯示更多

    收起更多

  • 亞細胞定位：
    Apical cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Cation transport ATPase (P-type) (TC 3.A.3) family, Type IIC subfamily
  • 組織特異性：
    Expressed in airway epithelial cells (at protein level). Found in skin and kidney. Detected in prostate basal cells (at protein level). Expression is increased in benign prostate hyperplasia and tumor tissues (at protein level).
  • 數據庫鏈接：

    HGNC: 13816

    OMIM: 182360

    KEGG: hsa:479

    STRING: 9606.ENSP00000218548

    UniGene: Hs.147111



主站蜘蛛池模板： 久久精品女人天堂av免费观看| 啪啪无码人妻丰满熟妇| 欧美黑人又粗又大又爽免费| 国产精品户外野外| 日韩精品无码视频一区二区蜜桃| 黑人大战中国av女叫惨了| 亚洲处破女av日韩精品| 日产乱码一区二区三区在线| 国语自产精品视频在 视频| 色欲天天婬色婬香综合网| 欧美寡妇xxxx黑人猛交| 国产女人高潮叫床视频| 中文人妻无码一区二区三区| 播五月开心婷婷欧美综合| 麻豆人妻无码性色av专区| 伊人久久精品无码av一区| 欧美亚洲国产一区二区三区| 99re6在线视频精品免费| 又色又爽又高潮免费观看| 极品粉嫩福利午夜在线播放 | 国产成年无码久久久久下载 | 国产高清午夜人成在线观看| 成 人 网 站94免费观看| 无人区一码卡二卡三乱码| 波多野结衣不打码视频| 精品国内自产拍在线观看视频| 日韩高清成片免费视频| 国产亚洲精品a久久777777| 国产精品无码aⅴ嫩草| 国产精品ⅴ无码大片在线看| 精品成人免费一区二区不卡| 欧美成aⅴ人高清免费观看| 亚洲人成图片小说网站| 最近更新中文字幕| 男女啪啪做爰高潮无遮挡| 亚洲午夜成人精品无码app| 欧美老妇疯狂xxxxbbbb| 亚洲精品久久久久玩吗| 亚洲欧美色一区二区三区| 日本又色又爽又黄的视频免 | 免费看女人与善牲交|