在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ATP12A Antibody, FITC conjugated

ATP12A Antibody, FITC conjugated

  • 中文名稱：
    ATP12A兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA002316LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) ATP12A Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    ATP12A antibody; ATP1AL1Potassium-transporting ATPase alpha chain 2 antibody; EC 7.2.2.19 antibody; Non-gastric H(+)/K(+) ATPase subunit alpha antibody; Proton pump antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Potassium-transporting ATPase alpha chain 2 protein (171-306AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    The catalytic subunit of a H(+)/K(+) ATPase and/or Na(+)/K(+) ATPase pump which transports K(+) ions in exchange for Na(+) and/or H(+) ions across the apical membrane of epithelial cells. Uses ATP as an energy source to pump K(+) ions into the cell while transporting Na(+) and/or H(+) ions to the extracellular compartment. Involved in the maintenance of electrolyte homeostasis through K(+) ion absorption in kidney and colon. In the airway epithelium, may play a primary role in mucus acidification regulating its viscosity and clearance.
  • 基因功能參考文獻：
    1. ATP12A knockdown or inhibition prevented the IL-13 dependent increase in airway surface liquid (ASL) viscosity but did not alter the ASL pH PMID: 29391451
    2. expressing human ATP12A in cystic fibrosis mouse airways acidified airway surface liquid, impaired defenses, and increased airway bacteria. PMID: 26823428
    3. Genetic association studies show that carriers of ATP12A rs10507337 C allele or CCTTC haplotype had better pattern of myocardial relaxation as compared to non-carriers. PMID: 25366262
    4. No significantly different expression levels could be detected in the various disease states compared to normal tissue. PMID: 22179016
    5. The presence of nongastric H-K-ATPase in rodent prostate apical membranes may indicate its involvement in potassium concentration regulation in secretions of these glands. PMID: 11880279
    6. Stimulation of protein kinase C pathway mediates endocytosis of human nongastric H+-K+-ATPase, ATP1AL1. PMID: 12110518
    7. Expressed in distal part of human colon and rectum, but also in proximal part of colon. Overexpressed in human colorectal adenocarcinomas adenocarcinomas. Astonishing levels of mRNA overexpression in carcinoma. PMID: 12230809
    8. Carboxy-terminus of HKalpha(2) facilitates proper folding of tHKalpha(2)/beta(1) complex allowing translocation of heterodimer to plasma membrane where potassium uptake occurs. Otherwise, alpha/beta complex is destined for degradation. PMID: 15086469
    9. non-gastric H(+)/K(+)ATPase is present in the microvillous plasma membrane of the transporting epithelia of the human placenta PMID: 15135233
    10. Inhibition of the ATP1AL1 isoenzyme of sodium potassium exchanging ATPase by 8-coumestrol is reported. PMID: 19487957
    11. Use of fold recognition methods enables a prediction that the C-terminal domain of the beta subunits of Na,K-ATPase and H,K-ATPase has an immunoglobulin-like fold, which resembles cell adhesion molecules. PMID: 19694409

    顯示更多

    收起更多

  • 亞細胞定位：
    Apical cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Cation transport ATPase (P-type) (TC 3.A.3) family, Type IIC subfamily
  • 組織特異性：
    Expressed in airway epithelial cells (at protein level). Found in skin and kidney. Detected in prostate basal cells (at protein level). Expression is increased in benign prostate hyperplasia and tumor tissues (at protein level).
  • 數據庫鏈接：

    HGNC: 13816

    OMIM: 182360

    KEGG: hsa:479

    STRING: 9606.ENSP00000218548

    UniGene: Hs.147111



主站蜘蛛池模板： 中字幕视频在线永久在线| 亚洲中文字幕久久无码精品| 中文字幕人妻a片免费看| 色综合欧美五月俺也去| 中文字幕一区在线观看视频| 亚洲伊人久久综合影院| 国产极品精品自在线| 国产无套水多在线观看| mm1313亚洲国产精品无码试看| 熟妇好大好深好满好爽| 成人看的污污超级黄网站免费| 人人妻碰人人免费| 1000部拍拍拍18勿入免费视频| 午夜不卡久久精品无码免费| 欧美孕妇变态孕交粗暴| 亚洲桃色天堂网| 成人丝袜激情一区二区| 精品无码中文视频在线观看 | 欧美成人精品一区二区三区色欲| 免费无遮挡无码永久在线观看视频| 亚洲情xo亚洲色xo无码| 成人国产网站v片免费观看| 成人无码α片在线观看不卡| 大色综合色综合网站| 漂亮人妻去按摩被按中出| 粉嫩虎白女毛片人体| 中文字幕韩国三级理论| 久久久久久久久久久久| 亚洲这里只有久热精品伊人| 国产午夜福利精品一区| 欧美性猛交xxxx乱大交3| 无码一区二区三区免费| 日日摸天天摸人人看| 国产精品美女久久久久| 久久天天躁狠狠躁夜夜躁2014 | 精品一区二区三区在线视频| 日日干夜夜干| 久久久www成人免费看片| 精品国产自在现线看久久| 国产肉体ⅹxxx137大胆| 国产福利姬喷水福利在线观看|