在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ATG4D Antibody

ATG4D Antibody

  • 中文名稱：
    ATG4D兔多克隆抗體
  • 貨號：
    CSB-PA774797LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: A549 whole cell lysate, Hela whole cell lysate, SH-SY5Y whole cell lysate, Mouse heart tissue
      All lanes: ATG4D antibody at 2.8µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 53, 17 kDa
      Observed band size: 53 kDa
    • IHC image of CSB-PA774797LA01HU diluted at 1:700 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • IHC image of CSB-PA774797LA01HU diluted at 1:700 and staining in paraffin-embedded human pancreatic tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of PC-3 cells with CSB-PA774797LA01HU at 1:233, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) ATG4D Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    9830134P12Rik antibody; APG4 autophagy 4 homolog D antibody; APG4 D antibody; APG4; S. cerevisiae; homolog of; D antibody; APG4D antibody; ATG4 autophagy related 4 homolog D (S. cerevisiae) antibody; Atg4d antibody; ATG4D_HUMAN antibody; Atg4dl antibody; AUT like 4 cysteine endopeptidase antibody; AUT-like 4 cysteine endopeptidase antibody; AUTL4 antibody; Autophagin 4 antibody; Autophagin-4 antibody; autophagy 4; S. cerevisiae; homolog of; D antibody; autophagy related 4D; cysteine peptidase antibody; Autophagy related cysteine endopeptidase 4 antibody; Autophagy related protein 4 homolog D antibody; Autophagy-related cysteine endopeptidase 4 antibody; Autophagy-related protein 4 homolog D antibody; Cysteine protease ATG4D antibody; Cysteine protease involved in autophagy antibody; MGC31226 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Cysteine protease ATG4D protein (14-43AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，ATG4D Antibody (CSB-PA774797LA01HU)，的標記方式是Non-conjugated。對于ATG4D Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA774797LB01HU ATG4D Antibody, HRP conjugated ELISA
    FITC CSB-PA774797LC01HU ATG4D Antibody, FITC conjugated
    Biotin CSB-PA774797LD01HU ATG4D Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:500-1:1000
    IF 1:200-1:500
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.; Plays a role as an autophagy regulator that links mitochondrial dysfunction with apoptosis. The mitochondrial import of ATG4D during cellular stress and differentiation may play important roles in the regulation of mitochondrial physiology, ROS, mitophagy and cell viability.
  • 基因功能參考文獻：
    1. study elucidated a novel Malat1-miR-101-STMN1/RAB5A/ATG4D regulatory network that Malat1 activates autophagy and promotes cell proliferation by sponging miR-101 and upregulating STMN1, RAB5A and ATG4D expression in glioma cells PMID: 28834690
    2. The actions of ATG4 family members (particularly ATG4B) are required for the control of autophagosome fusion with late, degradative compartments in differentiating human erythroblasts. PMID: 23508006
    3. the import of Atg4D during cellular stress and differentiation may play important roles in the regulation of mitochondrial physiology, reactive oxygen species, mitophagy and cell viability. PMID: 22441018
    4. Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis. PMID: 19549685
  • 亞細胞定位：
    [Cysteine protease ATG4D]: Cytoplasm.; [Cysteine protease ATG4D, mitochondrial]: Cytoplasm. Mitochondrion matrix.
  • 蛋白家族：
    Peptidase C54 family
  • 數據庫鏈接：

    HGNC: 20789

    OMIM: 611340

    KEGG: hsa:84971

    STRING: 9606.ENSP00000311318

    UniGene: Hs.512799



主站蜘蛛池模板： 午夜美女裸体福利视频| 亚洲一卡二卡三卡四卡| 在线看片免费人成视频久网| 色噜噜狠狼综合在线| 末成年毛片在线播放| 黄瓜视频在线观看网址| 欧美精品久久天天躁| 色偷拍 自怕 亚洲 10p| 中国精品无码免费专区午夜| 18禁免费吃奶摸下激烈视频| 风间由美性色一区二区三区| 欧洲多毛裸体xxxxx| 久久婷婷国产剧情内射白浆| 免费午夜男女高清视频| 国内a∨免费播放| 无码国内精品人妻少妇| 亚洲中文有码字幕青青| 国产成人无码短视频| 亚洲精品国产精华液| 国产一区二区三区在线蜜桃| 18禁裸男晨勃露j毛网站| 中文无码精品一区二区三区| 亚洲免费人成在线视频观看| 亚洲аv电影天堂网| 精品视频在线观自拍自拍| 久久久久久av无码免费看大片 | 日本黄页网站免费大全| 国产精品久久国产精品99 gif| 精产国品一区二区三产区| 无码人妻在线一区二区三区免费| 国产亚洲欧美在线专区| 天天躁日日躁狠狠躁超碰97| 玩肥熟老妇bbw视频| 九九久久精品国产| 偷拍区清纯另类丝袜美腿| 成人亚欧欧美激情在线观看| 亚洲中文久久精品无码1| 久久午夜无码鲁丝片午夜精品| 精品视频一区二区三三区四区| 亚洲成亚洲成网| 午夜人妻久久久久久久久|