在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ATG4D Antibody

ATG4D Antibody

  • 中文名稱：
    ATG4D兔多克隆抗體
  • 貨號：
    CSB-PA774797LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: A549 whole cell lysate, Hela whole cell lysate, SH-SY5Y whole cell lysate, Mouse heart tissue
      All lanes: ATG4D antibody at 2.8µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 53, 17 kDa
      Observed band size: 53 kDa
    • IHC image of CSB-PA774797LA01HU diluted at 1:700 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • IHC image of CSB-PA774797LA01HU diluted at 1:700 and staining in paraffin-embedded human pancreatic tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of PC-3 cells with CSB-PA774797LA01HU at 1:233, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) ATG4D Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    9830134P12Rik antibody; APG4 autophagy 4 homolog D antibody; APG4 D antibody; APG4; S. cerevisiae; homolog of; D antibody; APG4D antibody; ATG4 autophagy related 4 homolog D (S. cerevisiae) antibody; Atg4d antibody; ATG4D_HUMAN antibody; Atg4dl antibody; AUT like 4 cysteine endopeptidase antibody; AUT-like 4 cysteine endopeptidase antibody; AUTL4 antibody; Autophagin 4 antibody; Autophagin-4 antibody; autophagy 4; S. cerevisiae; homolog of; D antibody; autophagy related 4D; cysteine peptidase antibody; Autophagy related cysteine endopeptidase 4 antibody; Autophagy related protein 4 homolog D antibody; Autophagy-related cysteine endopeptidase 4 antibody; Autophagy-related protein 4 homolog D antibody; Cysteine protease ATG4D antibody; Cysteine protease involved in autophagy antibody; MGC31226 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Cysteine protease ATG4D protein (14-43AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，ATG4D Antibody (CSB-PA774797LA01HU)，的標記方式是Non-conjugated。對于ATG4D Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA774797LB01HU ATG4D Antibody, HRP conjugated ELISA
    FITC CSB-PA774797LC01HU ATG4D Antibody, FITC conjugated
    Biotin CSB-PA774797LD01HU ATG4D Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:500-1:1000
    IF 1:200-1:500
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.; Plays a role as an autophagy regulator that links mitochondrial dysfunction with apoptosis. The mitochondrial import of ATG4D during cellular stress and differentiation may play important roles in the regulation of mitochondrial physiology, ROS, mitophagy and cell viability.
  • 基因功能參考文獻：
    1. study elucidated a novel Malat1-miR-101-STMN1/RAB5A/ATG4D regulatory network that Malat1 activates autophagy and promotes cell proliferation by sponging miR-101 and upregulating STMN1, RAB5A and ATG4D expression in glioma cells PMID: 28834690
    2. The actions of ATG4 family members (particularly ATG4B) are required for the control of autophagosome fusion with late, degradative compartments in differentiating human erythroblasts. PMID: 23508006
    3. the import of Atg4D during cellular stress and differentiation may play important roles in the regulation of mitochondrial physiology, reactive oxygen species, mitophagy and cell viability. PMID: 22441018
    4. Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis. PMID: 19549685
  • 亞細胞定位：
    [Cysteine protease ATG4D]: Cytoplasm.; [Cysteine protease ATG4D, mitochondrial]: Cytoplasm. Mitochondrion matrix.
  • 蛋白家族：
    Peptidase C54 family
  • 數據庫鏈接：

    HGNC: 20789

    OMIM: 611340

    KEGG: hsa:84971

    STRING: 9606.ENSP00000311318

    UniGene: Hs.512799



主站蜘蛛池模板： 精品人妻午夜一区二区三区四区| 中文字幕无码专区人妻系列| 国产精品 中文字幕 亚洲 欧美| 青草青草视频2免费观看| 久久亚洲一区二区三区四区| 亚洲欧洲美色一区二区三区| 国产成人美女视频网站| 天天躁人人躁人人躁狂躁| 亚洲精品国产精品国自产观看| 国模小婕私拍鲜嫩玉门| 国产成人亚洲综合无码品善网| 国内嫩模私拍精品视频| 成人无码www免费视频| 18禁无遮挡无码网站免费| 女人高潮抽搐潮喷小视频 | 国产精品美女久久久久久2021| 久久久免费无码成人影片| 精品av无码国产一区二区| 亚洲精品国产嫩草在线观看东京热 | 18禁亚洲深夜福利入口| 日产精品一二三区| 日韩 欧美 动漫 国产 制服| 97人妻无码一区二区精品免费| 日本熟妇人妻xxxxx-欢迎您| 天天爽夜夜爽人人爽88| 护士奶头又白又大又好摸视频| 狂野欧美性猛xxxx乱大交| 国产成人亚洲日韩欧美| 18无码粉嫩小泬无套在线观看 | 一二三四视频社区在线| 午夜男女无遮掩免费视频| 国产精品毛片一区二区三区| 野狼av午夜福利在线| 亚洲偷自拍国综合色帝国| 国产成人午夜福利免费无码r| 狠狠躁天天躁中文字幕| 国产精品久久久久久久妇| 97久久国产成人免费网站| 久久av无码精品人妻糸列| 大香伊蕉国产av| 欧美兽交xxxx×视频|