在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ATG4D Antibody

  • 中文名稱:
    ATG4D兔多克隆抗體
  • 貨號:
    CSB-PA924465
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA924465(ATG4D Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA924465(ATG4D Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    9830134P12Rik antibody; APG4 autophagy 4 homolog D antibody; APG4 D antibody; APG4; S. cerevisiae; homolog of; D antibody; APG4D antibody; ATG4 autophagy related 4 homolog D (S. cerevisiae) antibody; Atg4d antibody; ATG4D_HUMAN antibody; Atg4dl antibody; AUT like 4 cysteine endopeptidase antibody; AUT-like 4 cysteine endopeptidase antibody; AUTL4 antibody; Autophagin 4 antibody; Autophagin-4 antibody; autophagy 4; S. cerevisiae; homolog of; D antibody; autophagy related 4D; cysteine peptidase antibody; Autophagy related cysteine endopeptidase 4 antibody; Autophagy related protein 4 homolog D antibody; Autophagy-related cysteine endopeptidase 4 antibody; Autophagy-related protein 4 homolog D antibody; Cysteine protease ATG4D antibody; Cysteine protease involved in autophagy antibody; MGC31226 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Fusion protein of Human ATG4D
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:1000-1:5000
    IHC 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.; Plays a role as an autophagy regulator that links mitochondrial dysfunction with apoptosis. The mitochondrial import of ATG4D during cellular stress and differentiation may play important roles in the regulation of mitochondrial physiology, ROS, mitophagy and cell viability.
  • 基因功能參考文獻:
    1. study elucidated a novel Malat1-miR-101-STMN1/RAB5A/ATG4D regulatory network that Malat1 activates autophagy and promotes cell proliferation by sponging miR-101 and upregulating STMN1, RAB5A and ATG4D expression in glioma cells PMID: 28834690
    2. The actions of ATG4 family members (particularly ATG4B) are required for the control of autophagosome fusion with late, degradative compartments in differentiating human erythroblasts. PMID: 23508006
    3. the import of Atg4D during cellular stress and differentiation may play important roles in the regulation of mitochondrial physiology, reactive oxygen species, mitophagy and cell viability. PMID: 22441018
    4. Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis. PMID: 19549685
  • 亞細胞定位:
    [Cysteine protease ATG4D]: Cytoplasm.; [Cysteine protease ATG4D, mitochondrial]: Cytoplasm. Mitochondrion matrix.
  • 蛋白家族:
    Peptidase C54 family
  • 數據庫鏈接:

    HGNC: 20789

    OMIM: 611340

    KEGG: hsa:84971

    STRING: 9606.ENSP00000311318

    UniGene: Hs.512799



主站蜘蛛池模板: 5566先锋影音夜色资源站在线观看| 妲己丰满人熟妇大尺度人体艺| 性动态图av无码专区| 老熟妇高潮一区二区三区| 亚洲综合激情另类小说区| 人妻少妇乱孑伦无码专区蜜柚| 性亚洲videofree高清| 日韩av午夜在线观看| 丰满诱人的人妻3| 国产巨大爆乳在线观看| 日本熟妇厨房bbw| 国产超碰人人爽人人做人人添| 亚洲国产综合无码一区| 久久亚洲人成电影网| 亚洲va中文字幕无码久久不卡| 精品一卡2卡三卡4卡免费网站| 人妻夜夜添夜夜无码av| 无码无遮挡又大又爽又黄的视频| 久久国产福利一区二区| 亚洲国产区男人本色vr| 乱中年女人伦av三区| 国产精品女同一区二区| 婷婷网亚洲色偷偷男人的天堂| 久久国产高潮流白浆免费观看| 欧洲精品99毛片免费高清观看| 国产精品福利视频一区| 久久国产精品2020免费| 奶头又大又白喷奶水av| 成 人影片 免费观看| 亚洲αv无码一区二区三区四区 | 人人妻人人澡av| 国产午夜福利在线播放| 亚洲国产v高清在线观看| 啪一啪射一射插一插| 全部孕妇毛片丰满孕妇孕交| 69精品国产久热在线观看| 97精品国产久热在线观看| 波多野结衣初尝黑人| 国语对白做受xxxxx在线中国 | 亚洲国产精品久久久久久久| 美女黄18以下禁止观看|