在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ATG4A Antibody

ATG4A Antibody

  • 中文名稱：
    ATG4A兔多克隆抗體
  • 貨號：
    CSB-PA006858
  • 規格：
    ￥1090
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    AI627006 antibody; APG4 autophagy 4 homolog A antibody; Apg4a antibody; ATG4 autophagy related 4 homolog A (S. cerevisiae) antibody; ATG4 autophagy related 4 homolog A antibody; ATG4A antibody; ATG4A_HUMAN antibody; Atg4al antibody; AUT like 2 cysteine endopeptidase antibody; AUT-like 2 cysteine endopeptidase antibody; Autl2 antibody; Autophagin 2 antibody; Autophagin-2 antibody; Autophagy related 4A cysteine peptidase antibody; Autophagy related cysteine endopeptidase 2 antibody; Autophagy related protein 4 homolog A antibody; Autophagy-related cysteine endopeptidase 2 antibody; Autophagy-related protein 4 homolog A antibody; AV169859 antibody; Cysteine protease ATG4A antibody; hAPG4A antibody; MGC107179 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human Atg4A.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, IHC, IF, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:20000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP. Has also an activity of delipidating enzyme for the PE-conjugated forms.
  • 基因功能參考文獻：
    1. An intron SNP rs807185 in ATG4A might be a protective factor for lung cancer. PMID: 26061994
    2. ATG4A promotes the metastasis of gastric cancer cells via the Notch signaling pathway, which is an autophagy-independent mechanism PMID: 27276686
    3. The structure and regulatory machinery of Atg4a [review] PMID: 28253956
    4. We conclude that miR-24-3p regulates autophagy by targeting ATG4A PMID: 25426560
    5. The autophagy regulator ATG4A was found to be essential for the maintenance of a sub-population with cancer stem cell properties and to regulate breast cancer cell tumourigenicity. PMID: 24229464
    6. The demonstration that expression of ATG4A in cells increased stem properties provided an indication of its biological function. Hypomethylation of ATG4A and HIST1H2BN in ovarian tumor-initiating cells predicts poor prognosis for ovarian cancer patients. PMID: 24256813
    7. no association between SNP rs807185 and the presence of granulomas in Crohn's disease PMID: 21122541
    8. statistical analysis of APG4A gene confirmed the characterisation of each protein-coding gene present in human genome Xq22.1 PMID: 21297227
    9. Atg4B possessed the broadest spectrum against all substrates, followed by Atg4A for ATG8 substrates PMID: 21177865
    10. HsApg4A cleaves the COOH terminus of GATE-16 PMID: 12473658
    11. The cysteine protease HsAtg4 is identified as a direct target for oxidation by hydrogen peroxide, and a cysteine residue located near the HsAtg4 catalytic site as critical for this regulation. PMID: 17347651

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    Peptidase C54 family
  • 數據庫鏈接：

    HGNC: 16489

    OMIM: 300663

    KEGG: hsa:115201

    STRING: 9606.ENSP00000361306

    UniGene: Hs.8763



主站蜘蛛池模板： 国产精品va无码一区二区| 国产av一区最新精品| 亚洲第一a在线观看网站| 国产亚洲精品久久久久久国| 熟妇人妻av无码一区二区三区| 一本色道久久99一综合| 婷婷色婷婷开心五月四房播播久久| 国产丝袜足j在线视频播放| 豆国产97在线 | 亚洲| 欧洲成人午夜精品无码区久久| 精品一卡2卡3卡4卡新区在线 | 国产 制服丝袜 动漫在线| 成人美女黄网站色大色费全看| 国产三区在线成人av| 邻居少妇张开双腿让我爽一夜| 国产精品天干天干| 国产又色又爽又黄的在线观看| 亚洲精品国产自在现线看| 精品无码av不卡一区二区三区 | 西西人体午夜大胆无码视频| 亚洲人禽杂交av片久久| 成在人线av无码免观看| 美女内射视频www网站午夜| 中文字幕人妻中文av不卡专区| 亚洲精品av无码喷奶水网站| 超caopor在线公开视频| 国产情侣草莓视频在线| 人妻在客厅被c的呻吟| 3d动漫精品啪啪一区二区下载| 成视频年人黄网站免费视频| 在线a亚洲v天堂网2018| 中文人妻av大区中文不卡| 成人国产精品无码网站| 人妻少妇邻居少妇好多水在线| 欧美mv日韩mv国产网站app| 黑人玩弄出轨人妻松雪| 影音先锋亚洲成aⅴ人在| 日韩亚洲国产激情一区浪潮av| 国产成人精品日本亚洲999| 国产av毛片亚洲含羞草社| 久久久综合九色综合鬼色|