在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ATG2B Antibody

ATG2B Antibody

  • 中文名稱：
    ATG2B兔多克隆抗體
  • 貨號：
    CSB-PA822186LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunofluorescence staining of HepG2 cells with CSB-PA822186LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
    • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA822186LA01HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) ATG2B Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    2410024A21Rik antibody; AI047755 antibody; AI503411 antibody; ATG2 autophagy related 2 homolog B antibody; Atg2b antibody; ATG2B_HUMAN antibody; Autophagy-related protein 2 homolog B antibody; AW558123 antibody; C030004M05Rik antibody; C14orf103 antibody; C630028L02Rik antibody; FLJ10242 antibody; KIAA4067 antibody; mKIAA4067 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Autophagy-related protein 2 homolog B protein (1357-1536AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，ATG2B Antibody (CSB-PA822186LA01HU)，的標記方式是Non-conjugated。對于ATG2B Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA822186LB01HU ATG2B Antibody, HRP conjugated ELISA
    FITC CSB-PA822186LC01HU ATG2B Antibody, FITC conjugated
    Biotin CSB-PA822186LD01HU ATG2B Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Lipid transfer protein required for both autophagosome formation and regulation of lipid droplet morphology and dispersion. Tethers the edge of the isolation membrane (IM) to the endoplasmic reticulum (ER) and mediates direct lipid transfer from ER to IM for IM expansion. Binds to the ER exit site (ERES), which is the membrane source for autophagosome formation, and extracts phospholipids from the membrane source and transfers them to ATG9 (ATG9A or ATG9B) to the IM for membrane expansion. Lipid transfer activity is enhanced by WDR45/WIPI4, which promotes ATG2B-association with phosphatidylinositol 3-monophosphate (PI3P)-containing membranes.
  • 基因功能參考文獻：
    1. Authors demonstrate that inhibition of autophagosome completion by Atg2A/B deletion accumulates immature autophagosomal membranes that promote non-canonical caspase-8 activation in response to nutrient starvation via an intracellular death-inducing signaling complex (iDISC). PMID: 28800131
    2. This study highlights the transcriptional inactivation mechanisms of ATG2B, ATG4D, ATG9A and ATG9B promoter methylation status and the possible origin of autophagy signal pathway repression in invasive ductal carcinomas. PMID: 27265029
    3. demonstrate that overexpression of ATG2B and GSKIP enhances hematopoietic progenitor differentiation, including of megakaryocytes, by increasing progenitor sensitivity to thrombopoietin PMID: 26280900
    4. miR-143 inhibits cell proliferation by targeting autophagy-related 2B in non-small cell lung cancer H1299 cells. PMID: 25322940
    5. Depletion of both Atg2A and Atg2B causes clustering of enlarged lipid droplets in an autophagy-independent manner. These data suggest that mammalian Atg2 proteins function both in autophagosome formation and regulation of lipid droplet morphology and dispersion. PMID: 22219374
    6. miR-130a inhibited autophagy by reducing autophagosome formation, an effect mediated by downregulation of the genes ATG2B and DICER1. PMID: 22350415

    顯示更多

    收起更多

  • 亞細胞定位：
    Preautophagosomal structure membrane; Peripheral membrane protein. Lipid droplet. Endoplasmic reticulum membrane; Peripheral membrane protein.
  • 蛋白家族：
    ATG2 family
  • 數據庫鏈接：

    HGNC: 20187

    OMIM: 616226

    KEGG: hsa:55102

    STRING: 9606.ENSP00000353010

    UniGene: Hs.168241



主站蜘蛛池模板： 无码国产精成人午夜视频一区二区 | 国产精品人妻一区二区高| 国产美女在线精品免费观看网址| 国产做无码视频在线观看| 天堂网www天堂在线资源| 乱子伦农村xxxxbbb| 一边吃奶一边做动态图| 俺也来俺也去俺也射| 中出あ人妻熟女中文字幕| 亚洲精品人成网线在播放va| 国产熟人av一二三区| 无码一区二区波多野结衣播放搜索| 日韩国产精品无码一区二区三区| 伊人精品成人久久综合97| 日本少妇高潮喷水xxxxxxx| 日躁夜躁狠狠躁2001| 午夜性色吃奶添下面69影院 | 久久久久人妻一区精品性色av | 国产精品vr虚拟专区| 国产成人片无码视频在线观看| 国产精品久久久久久久久人妻| 亚洲熟少妇在线播放999| 国产卡一卡二卡三精品| 无码粉嫩虎白一线天在线观看| 麻豆国产尤物av尤物在线观看| 18勿入网站免费永久| 老熟女重囗味hdxx70星空| www夜片内射视频日韩精品成人| 97视频热人人精品免费| 麻豆国产成人av高清在线| 欧美成人精品第一区二区三区| 亚洲欧美日韩综合久久| 久久天天躁狠狠躁夜夜96流白浆 | 天天摸夜夜摸夜夜狠狠摸| 欧美xxxx做受欧美1314| 人人莫人人擦人人看| 国产精品麻豆欧美日韩ww| 国产日韩精品欧美2020区| 精品国产中文字幕在线视频| 国产猛烈高潮尖叫视频免费| 亚洲天堂2017无码|