在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ARPC2 Antibody

ARPC2 Antibody

  • 中文名稱：
    ARPC2兔多克隆抗體
  • 貨號：
    CSB-PA03365A0Rb
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA03365A0Rb at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) ARPC2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    Actin related protein 2/3 complex subunit 2 34kDa antibody; Actin related protein 2/3 complex subunit 2 antibody; Actin-related protein 2/3 complex subunit 2 antibody; ARC 34 antibody; ARC34 antibody; Arp2/3 complex 34 kDa subunit antibody; ARP2/3 protein compex subunit 34 antibody; ARPC 2 antibody; Arpc2 antibody; ARPC2_HUMAN antibody; p34 Arc antibody; p34-ARC antibody; p34Arc antibody; PNAS 139 antibody; PNAS139 antibody; PRO 2446 antibody; PRO2446 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Actin-related protein 2/3 complex subunit 2 protein (1-250AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，ARPC2 Antibody (CSB-PA03365A0Rb)，的標(biāo)記方式是Non-conjugated。對于ARPC2 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA03365B0Rb ARPC2 Antibody, HRP conjugated ELISA
    FITC CSB-PA03365C0Rb ARPC2 Antibody, FITC conjugated
    Biotin CSB-PA03365D0Rb ARPC2 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the mother actin filament. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).
  • 基因功能參考文獻(xiàn)：
    1. In the association analysis of 110 gastric cancer tissues, ARPC2 showed significant associations with large tumor size, lymph node invasion, and high tumor stage. In addition, ARPC2-positive patients exhibited lower RFS and OS rates compared with ARPC2-negative patients. We thus identify that ARPC2 plays an aneretic role in human gastric cancer and provided a new target for gastric cancer therapy. PMID: 28694563
    2. Downregulation of the ARP2/3 complex signaling pathway, a common final pathway for multiple signaling cascades that regulate the actin cytoskeleton, would compromise the structural stability of spines, leading to their loss. In concert with findings from deletion of the ARP2/3 complex in mice, these findings support the idea that spine deficits in the DLPFC may contribute to subcortical hyperdopaminergia in schizophrenia. PMID: 27523502
    3. Recent reports now demonstrate a novel aspect of the ARP2/3 complex and the nucleating-promoting factors in the maintenance of endothelial barrier function and junction remodeling of established endothelial cell junctions. PMID: 24621569
    4. FOXF1 repressed cell growth and expression of collagen-1 and actin-related protein 2/3 complex, subunit 2. PMID: 25260753
    5. The Arp2/3 complex is recruited to invading Rickettsia parkeri and is required for efficient invasion. PMID: 22188208
    6. Filopodia initiation: focus on the Arp2/3 complex and formins PMID: 21975549
    7. WASH is a bimodular protein and a component of the BLOC-1 complex in which the C terminus is involved in Arp2/3-mediated actin nucleation, whereas the N-terminal portion is required for its regulation and localization in the cells PMID: 20308062
    8. The actin-related protein 2 accumulated in punctate structures that formed an extensivenetwork in a region corresponding to the postition of the Golgi complex. PMID: 15793564
    9. Compared with controls, actin-related protein 2/3 level was markedly increased in brains of intractable epilepsy patients. PMID: 18708039
    10. These findings strongly suggest that defective IL10 function is central to the pathogenesis of the ulcerative colitis subtype of inflammatory bowel disease. PMID: 18836448

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm, cytoskeleton. Cell projection. Cell junction, synapse, synaptosome. Nucleus.
  • 蛋白家族：
    ARPC2 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 705

    OMIM: 604224

    KEGG: hsa:10109

    STRING: 9606.ENSP00000295685

    UniGene: Hs.529303



主站蜘蛛池模板： 日日天日日夜日日摸| 国产一区二区在线视频| 麻豆亚洲国产成人精品无码区 | 无码h肉动漫在线观看免费| 亚洲偷精品国产五月丁香麻豆| 国产在线观看无码免费视频| 精品国产一区二区三区香蕉| 欧美日韩不卡视频合集| 国产福利萌白酱精品一区| 欧美日韩亚洲国产欧美电影| 污污污污污污www网站免费| 亚洲成色在线综合网站| 亚洲欧洲国产综合aⅴ无码| 免费国产在线精品一区二区三区 | 国产人妻精品一区二区三首| 亚洲色大成网站www国产| 国产亚洲精品久久久久秋霞| 男女啪啪免费观看的网址| 717影院理论午夜伦八戒| 亚洲人成在线影院| 中文乱码人妻系列一区二区| 亚洲成在人线在线播放无码vr| 在线精品自偷自拍无码中文| 午夜精品久久久久久久无码| 亚洲熟女乱综合一区二区在线| 亚洲加勒比少妇无码av| 狠狠躁夜夜躁人人躁婷婷视频| 高h纯肉无码视频在线观看| 婷婷色爱区综合五月激情| 亚洲图片小说激情综合| 成人毛片100部免费看| 亚洲一区激情校园小说| 亚洲а∨天堂久久精品| 亚洲人成小说网站色| 国产佗精品一区二区三区| 欧洲熟妇色xxxx欧美老妇老头多毛| 亚洲丁香五月激情综合| 国产精品人成视频免费播放| 内射中出日韩无国产剧情| 色avav色av爱avav亚洲色拍 | 久久久中文久久久无码|