在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ARHGEF3 Antibody

  • 中文名稱:
    ARHGEF3兔多克隆抗體
  • 貨號:
    CSB-PA878863ESR2HU
  • 規格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: ARHGEF3 antibody at 2.21µg/ml
      Lane 1: MCF-7 whole cell lysate
      Lane 2: HepG2 whole cell lysate
      Lane 3: Jurkat whole cell lysate
      Lane 4: Hela whole cell lysate
      Lane 5: 293T whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 60, 64, 61, 37 kDa
      Observed band size: 60 kDa
    • Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA878863ESR2HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) ARHGEF3 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    ARHGEF3
  • 別名:
    ARHGEF3 antibody; Rho guanine nucleotide exchange factor 3 antibody; Exchange factor found in platelets and leukemic and neuronal tissues antibody; XPLN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Rho guanine nucleotide exchange factor 3 protein (287-526AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Acts as guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases.
  • 基因功能參考文獻:
    1. This is the first study describing the involvement of XPLN in the regulation of the mTORC2-SPARC axis, and these findings may help uncover regulatory mechanisms mediated by XPLN in idiopathic pulmonary fibrosis PMID: 28315487
    2. Our findings suggest that increased expression of ARHGEF3 plays a critical oncogenic role in nasopharyngeal carcinoma pathogenesis PMID: 27028992
    3. Data suggest that modulation of ARHGEF3 gene expression in humans with a promoter-localized SNP plays a role in human megakaryocytes and human platelet function-a finding resulting from the biological follow-up of human genetic studies. Arhgef3 KO mice partially recapitulate the human phenotype. PMID: 28542600
    4. ARHGEF3 has a crucial role in myeloid differentiation. PMID: 25494542
    5. ARHGEF3 and RHOA are potential regulators of a number of genes in bone cells, with influences on ACTA2 evident in both osteoblast-like and osteoclast-like cells. PMID: 24840563
    6. XPLN is an endogenous inhibitor of mTORC2. PMID: 24043828
    7. the association between rs7646054 in ARHGEF3 and bone mineral density observed in Caucasians was not replicated in the chinese samples. PMID: 19727905
    8. a guanine nucleotide exchange factor for RhoA and RhoB, but not RhoC PMID: 12221096
    9. genetic variation in ARHGEF3 plays a role in the determination of bone density in Caucasian women. This data implicates the RhoGTPase-RhoGEF pathway in osteoporosis. PMID: 18499081

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 組織特異性:
    Widely expressed. Highest levels are found in adult brain and skeletal muscle. Lower levels are found in heart and kidney.
  • 數據庫鏈接:

    HGNC: 683

    OMIM: 612115

    KEGG: hsa:50650

    STRING: 9606.ENSP00000341071

    UniGene: Hs.476402



主站蜘蛛池模板: 久久久亚洲精华液精华液精华液| 奇米影视7777狠狠狠狠影视| 亚洲精品中文字幕一区二区三区| 天干夜天干天天天爽视频| 国产亚洲精品久久久久蜜臀| 99久久精品国产一区二区三区| 98色婷婷在线| 成 人 社区在线视频| 精品久久久久久久中文字幕| 亚洲国产成人久久综合一区| 国产成+人+综合+亚洲欧美丁香花| 欧美人禽杂交狂配免费看| 97国产色伦在色在线播放| 国产乱子影视频上线免费观看| 国产v亚洲v天堂无码久久久 | 亚洲精品卡2卡三卡4卡2卡乱码 | 久久www色情成人免费| 97国产在线看片免费人成视频| 国内老熟妇乱子伦视频| 亚洲精品国产精品国自产观看| 国产一区二区精品久久岳| 免费无码av片在线观看国产| 久久亚洲色www成人男男| 丰满人妻熟妇乱又仑精品| 欧美精品色婷婷五月综合| 999久久久无码国产精品| 人妻无码一区二区三区tv| 野外被强j到高潮免费观看| 夜夜揉揉日日人人| 欧美日韩综合一区二区三区| 国产99在线 | 中文| 亚洲成a人v欧美综合天堂下载| 韩国和日本免费不卡在线v| 国产伦理一区二区| 97色偷偷色噜噜狠狠爱网站97| 无码不卡中文字幕av| 最激烈的床震娇喘视频出水| 毛片无码国产| 女人18毛片水真多免费看| 韩国 日本 亚洲 国产 不卡| 各种少妇正面bbw撒尿|