在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ARHGAP26 Antibody

  • 中文名稱:
    ARHGAP26兔多克隆抗體
  • 貨號:
    CSB-PA892479ESR1HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA892479ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA892479ESR1HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) ARHGAP26 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    ARHGAP26
  • 別名:
    arhgap26 antibody; FLJ42530 antibody; GRAF antibody; GRAF1 antibody; GTPase regulator associated with focal adhesion kinase antibody; GTPase regulator associated with focal adhesion kinase pp125(FAK) antibody; KIAA0621 antibody; oligophrenin 1 like protein antibody; Oligophrenin-1-like protein antibody; oligophrenin1like protein antibody; OPHN1L antibody; OPHN1L1 antibody; RHG26_HUMAN antibody; Rho GTPase activating protein 26 antibody; Rho GTPase activating protein26 antibody; Rho GTPase-activating protein 26 antibody; Rho-type GTPase-activating protein 26 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Rho GTPase-activating protein 26 protein (625-814AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    GTPase-activating protein for RHOA and CDC42.
  • 基因功能參考文獻:
    1. GRAF1 plays a role in the maintenance of normal epithelial phenotype and its depletion leads to an epithelial-mesenchymal transition-like process that might be involved in neoplastic transformation. PMID: 27588930
    2. We conclude that a transient interaction between Cdc42 and GRAF1 drives endocytic turnover and controls the transition essential for endosomal maturation of plasma membrane internalised by this mechanism. PMID: 26446261
    3. GRAF expression is a favorable prognostic marker in patients with acute myeloid leukemia. PMID: 25088035
    4. ADAR1 regulates the expression of ARHGAP26 through A-to-I RNA editing by disrupting the binding of miR-30b-3p and miR-573 within the 3' UTR of ARHGAP26. PMID: 24067935
    5. proposed that GRAF1 remodels membrane microdomains at adhesion sites into endocytic carriers, facilitating membrane turnover during cell morphological changes PMID: 21965292
    6. Findings suggest that the hypermethylation of GRAF promoter might be one of early events in the development of AML. PMID: 21074269
    7. a GTPase-activating protein that regulates muscle maturation and to highlight the functional importance of BAR domains in myotube formation PMID: 21622574
    8. Decreased level of GRAF transcript is associated with acute myeloid leukemia, myelodysplastic syndrome and chronic myeloid leukemia. PMID: 20704716
    9. The GRAF gene was down-regulated in AML, which might play a role in the leukemogenesis. PMID: 20533268
    10. The analysis of the expression pattern of the GRAF1/OPHN-1-L gene in human tissues and organs revealed the predominant brain expression of a novel splicing isoform. PMID: 20602808
    11. abnormal GRAF methylation might be an adverse prognostic event in MDS PMID: 20374274
    12. Graf residues important for the structural integrity are critical for binding RhoA and for the catalytic activity of GAP, but GTPase selectivity appears to be modulated by a more subtle interplay involving residues on the periphery of the main interface. PMID: 18929667
    13. GRAF is a negative regulator of RhoA in vivo, it acts as a GTP-ase activating protein (GAP) for RhoA and may be a downstream effector of RhoA in certain cell types. PMID: 9858476

    顯示更多

    收起更多

  • 相關疾病:
    Leukemia, juvenile myelomonocytic (JMML)
  • 亞細胞定位:
    Cell junction, focal adhesion. Cytoplasm, cytoskeleton.
  • 數據庫鏈接:

    HGNC: 17073

    OMIM: 605370

    KEGG: hsa:23092

    STRING: 9606.ENSP00000274498

    UniGene: Hs.654668



主站蜘蛛池模板: 好男人www社区| 欧美人与动人物牲交免费观看久久| 98国产精品综合一区二区三区| 亚洲国产成人va在线观看天堂| 9九色桋品熟女内射| 亚洲欧美中文字幕5发布 | 精品国产亚洲一区二区三区| 色翁荡熄又大又硬又粗又视频| 少妇被粗大的猛进69视频| 大肉大捧一进一出视频出来呀| 2021久久精品国产99国产精品| 在线精品亚洲一区二区| 精品无码国产自产在线观看水浒传 | 51国偷自产一区二区三区| 欧美性猛交xxxx免费视频软件| 狠狠躁夜夜躁人人躁婷婷 | 亚洲欧美成αⅴ人在线观看| 成人国产精品一区二区免费看| 成人欧美一区二区三区| 欧美freesex黑人又粗又大| 午夜视频无码国产在线观看| 久久久久青草线蕉亚洲麻豆| 99精品国产福利一区二区| 免费网站观看www在线观看| 国产成人av无码精品| 亚洲国产精品一区二区久久hs | 边吃奶边添下面好爽| 强奷人妻日本中文字幕| 国产成人8x人网站视频在线观看| 亚洲高清成人av电影网站 | 欧美老熟妇xb水多毛多| 少妇被粗大的猛烈进出图片 | 久久午夜伦鲁片免费无码| 玩弄中年熟妇正在播放| 成在线人av免费无码高潮喷水| 国偷自产av一区二区三区| 中文人妻av久久人妻水密桃| 国产美女口爆吞精普通话| 免费人成视频19674不收费| 久久综合九色欧美综合狠狠 | 亚洲国产精品久久久久婷婷老年|