在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ARAP3 Antibody, HRP conjugated

  • 中文名稱:
    ARAP3兔多克隆抗體, HRP偶聯(lián)
  • 貨號:
    CSB-PA819904LB01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) ARAP3 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    ARAP3 antibody; CENTD3 antibody; Arf-GAP with Rho-GAP domain antibody; ANK repeat and PH domain-containing protein 3 antibody; Centaurin-delta-3 antibody; Cnt-d3 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 protein (163-320AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能:
    Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Acts on ARF6, RAC1, RHOA and CDC42. Plays a role in the internalization of anthrax toxin.
  • 基因功能參考文獻(xiàn):
    1. Structural Basis for the Specific Recognition of RhoA by the Dual GTPase-activating Protein ARAP3. PMID: 27311713
    2. structural and binding affinity between odin and arap3 PMID: 23239578
    3. Phosphoinositide 3-OH kinase (PI3K) is input into the regulation of beta2 integrin activity, and processes dependent on its responses, by signaling through its effector ARAP3. PMID: 23180820
    4. The structural basis for the interaction between Arap3 and Vav2, hydrophobic pockets and binding specificity. PMID: 22750419
    5. ARAP3 is a unique Src substrate that suppresses peritoneal dissemination of scirrhous gastric carcinoma cells. PMID: 21076469
    6. None of the individual PH domains can bind to PtdIns(3,4,5)P3; rather, a fragment comprising two PH domains and an N-terminal linker is minimally required for binding. PMID: 19786092
    7. The catalytic domain of ARF-GAP alone is sufficient to initiate uncoating of liposome-derived COPI-coated vesicles. ARF-GAP activity is not required for COPI coat assembly & does not seem to be an essential coat component of COPI vesicles. PMID: 12832619
    8. ARAP3 has a role in integrin-mediated tyrosine kinase signalling pathways controlling Rho GTPases and cell spreading PMID: 15546919
    9. ARAP3 deficiency produced by antisense expression of an ARAP3 EST impaired entry of anthrax PA and its bound toxigenic moieties into both human and mouse cells, resulting in reduced toxin sensitivity PMID: 15569923
    10. In a yeast two-hybrid screen for new interaction partners of Arap3, the PI 5'-phosphatase SHIP2 was identified as an interaction partner of Arap3. PMID: 17314030

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cytoplasm. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein. Cell projection, lamellipodium. Cell projection, ruffle.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 24097

    OMIM: 606647

    KEGG: hsa:64411

    STRING: 9606.ENSP00000239440

    UniGene: Hs.726187



主站蜘蛛池模板: 国产高清视频色拍| 成全世界免费高清观看| 亚洲va无码va在线va天堂| 2019亚洲午夜无码天堂| 久久精品人妻中文系列| 久久精品人妻无码一区二区三区 | 亚洲精品无码少妇30p| 人与性动交aaaabbbb| 亚洲日韩v无码中文字幕| 大桥未久亚洲一区二区| 女人摸下面自熨视频在线播放| 欧美日韩在大午夜爽爽影院| 久久人妻内射无码一区三区| 日本边添边摸边做边爱喷水| 成年黄页网站大全免费无码| 开心婷婷五月激情综合社区| 日产一区日产2区| 99久久精品国产成人综合| 国产色诱视频在线播放网站| 久久精品www人人爽人人| 亚洲国产精品国自产拍av | 爽爽精品dvd蜜桃成熟时电影院 | 欧美乱妇xxxxxbbbbb| 久久亚洲欧美国产精品| 国产一区二区三区自产| 天天综合色天天综合色hd| 成年美女黄网站色大免费视频 | 少妇饥渴偷公乱av在线观看涩爱| 好紧好爽好深再快点av在线| 日本无遮挡吸乳视频| 色欲麻豆国产福利精品| 男女啪啪无遮挡免费网站| 99在线精品视频观看免费| 国产精品久久久久久妇女6080| 色哟哟在线视频精品一区| 日韩高清在线观看永久| 久久精品国产99精品国产亚洲性色 | 日本大片免费观看视频| 99久久久精品免费观看国产| 日韩人妻无码一区二区三区综合部| 久久综合久久自在自线精品自|