在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ARAP3 Antibody, HRP conjugated

  • 中文名稱:
    ARAP3兔多克隆抗體, HRP偶聯(lián)
  • 貨號:
    CSB-PA819904LB01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) ARAP3 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    ARAP3 antibody; CENTD3 antibody; Arf-GAP with Rho-GAP domain antibody; ANK repeat and PH domain-containing protein 3 antibody; Centaurin-delta-3 antibody; Cnt-d3 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 protein (163-320AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能:
    Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Acts on ARF6, RAC1, RHOA and CDC42. Plays a role in the internalization of anthrax toxin.
  • 基因功能參考文獻(xiàn):
    1. Structural Basis for the Specific Recognition of RhoA by the Dual GTPase-activating Protein ARAP3. PMID: 27311713
    2. structural and binding affinity between odin and arap3 PMID: 23239578
    3. Phosphoinositide 3-OH kinase (PI3K) is input into the regulation of beta2 integrin activity, and processes dependent on its responses, by signaling through its effector ARAP3. PMID: 23180820
    4. The structural basis for the interaction between Arap3 and Vav2, hydrophobic pockets and binding specificity. PMID: 22750419
    5. ARAP3 is a unique Src substrate that suppresses peritoneal dissemination of scirrhous gastric carcinoma cells. PMID: 21076469
    6. None of the individual PH domains can bind to PtdIns(3,4,5)P3; rather, a fragment comprising two PH domains and an N-terminal linker is minimally required for binding. PMID: 19786092
    7. The catalytic domain of ARF-GAP alone is sufficient to initiate uncoating of liposome-derived COPI-coated vesicles. ARF-GAP activity is not required for COPI coat assembly & does not seem to be an essential coat component of COPI vesicles. PMID: 12832619
    8. ARAP3 has a role in integrin-mediated tyrosine kinase signalling pathways controlling Rho GTPases and cell spreading PMID: 15546919
    9. ARAP3 deficiency produced by antisense expression of an ARAP3 EST impaired entry of anthrax PA and its bound toxigenic moieties into both human and mouse cells, resulting in reduced toxin sensitivity PMID: 15569923
    10. In a yeast two-hybrid screen for new interaction partners of Arap3, the PI 5'-phosphatase SHIP2 was identified as an interaction partner of Arap3. PMID: 17314030

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cytoplasm. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein. Cell projection, lamellipodium. Cell projection, ruffle.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 24097

    OMIM: 606647

    KEGG: hsa:64411

    STRING: 9606.ENSP00000239440

    UniGene: Hs.726187



主站蜘蛛池模板: 色欲av伊人久久大香线蕉影院 | 久久久亚洲欧洲日产国码农村| 国产精品人成视频国模| 四虎成人永久在线精品免费| 成人无码av网站在线观看| 精品人无码一区二区三区| 永久免费的av在线电影网无码| 欧美性黑人极品hd另类| 国产360激情盗摄全集| 人人摸人人搞人人透| 欧美大胆少妇bbw| 西西人体444www大胆无码视频| 免费观看啪啪黄的网站| 欧美婷婷六月丁香综合| 高清国产av一区二区三区| 日本中文字幕乱码免费| 中文有码亚洲制服av片| 国产suv精品一区二区五| 很色很爽很黄裸乳视频| 免费无码又爽又刺激一高潮| 国产成人亚洲综合色婷婷秒播| 中文字幕精品一二三四五六七八| 无码国产精品一区二区免费式直播| 久久综合色之久久综合| 天天狠天天透天干天干| 无码ol丝袜高跟秘书在线观看| 少妇的丰满人妻hd高清| 国产无套中出学生姝| 肉大捧一进一出免费视频| 一区二三区国产好的精华液o9| 久久天堂av综合合色| 亚洲天堂男人影院| 免费国产黄网站在线观看视频 | www内射国产在线观看| 717影院理论午夜伦八戒| 丰满熟妇被猛烈进入高清片| 免费纯肉3d动漫无码网站| 日产无码中文字幕av| 中文字幕精品亚洲无线码vr| 国产精品videossex国产高清 | 精品久久久久久综合日本|