在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. APIP Antibody

APIP Antibody

  • 中文名稱：
    APIP兔多克隆抗體
  • 貨號：
    CSB-PA921015
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA921015(APIP Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 60 μg, Lane: Mouse heart tissue, Primary antibody: CSB-PA921015(APIP Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    APIP
  • 別名：
    Apaf1 Interacting Protein antibody; APAF1-interacting protein antibody; APIP antibody; APIP2 antibody; CG129 antibody; CGI 29 antibody; CGI29 antibody; dJ179L10.2 antibody; MMRP19 antibody; Monocyte/macrophage protein 19 antibody; MTNB_HUMAN antibody; MTRu 1 P dehydratase antibody; MTRu-1-P dehydratase antibody; Probable methylthioribulose 1 phosphate dehydratase antibody; Probable methylthioribulose-1-phosphate dehydratase antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human APIP
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:500-1:5000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death.
  • 基因功能參考文獻：
    1. Results suggest that APIP stimulates cell proliferation via ERBB3, acting in conjunction with ERBB2, in gastric cancer cells. PMID: 26942872
    2. APIP/MtnB functions as a cell death inhibitor independently of its MtnB enzyme activity for apoptosis induced by either hypoxia or etoposide, but dependently for caspase-1-induced pyroptosis PMID: 24367089
    3. these results confirm the involvement of APIP in the methionine salvage pathway, which plays a key role in many biological functions like cancer, apoptosis, microbial proliferation and inflammation. PMID: 23285211
    4. human APIP was overproduced in Escherichia coli, purified and crystallized. An X-ray diffraction data set was collected to 2.40 A resolution PMID: 23192037
    5. A polymorphism associated with reduced expression of a putative methionine salvage pathway dehydratase, apoptotic protease activating factor 1 (APAF1)-interacting protein (APIP), was associated with increased caspase-1-mediated cell death in Salmonella. PMID: 22837397
    6. The down-regulation of APIP and UACA expression suggests that the threshold to activate the apoptosome apparatus may be decreased in non-small cell lung cancer cells. PMID: 22407486
    7. APIP functions to inhibit muscle ischemic damage by binding to Apaf-1 in the Apaf-1/caspase-9 apoptosis pathway. PMID: 15262985

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    Aldolase class II family, MtnB subfamily
  • 組織特異性：
    Isoform 1 is ubiquitously expressed. Isoform 2 is expressed at lower levels and detected in heart, brain, pancreas, liver, placenta, skeletal muscle and kidney.
  • 數據庫鏈接：

    HGNC: 17581

    OMIM: 612491

    KEGG: hsa:51074

    STRING: 9606.ENSP00000379133

    UniGene: Hs.447794



主站蜘蛛池模板： 无码写真精品永久福利在线| 久久99亚洲精品久久99果| 国模无码视频一区| 亚洲中文字幕在线第二页| 688欧美人禽杂交狂配 | 女人高潮抽搐喷液30分钟视频 | 亚洲国产成人va在线观看天堂| 久久爱www人成狠狠爱综合网| 英语老师丝袜娇喘好爽视频| 免费欧洲美女牲交视频 | 伊人久久大香线蕉av最新| 成人看片黄a免费看| 国产欧美亚洲精品a| 日韩一区二区在线观看视频| 99热亚洲色精品国产88| 日本动漫瀑乳h动漫啪啪免费| 精品无人区无码乱码毛片国产| 亚洲精品一区二区三区婷婷月| 日日天日日夜日日摸| 中文字幕中文乱码www| 国产v亚洲v天堂a无码| 97影院理论午夜伦不卡| 东京一本一道一二三区| 日本亚洲欧洲无免费码在线| 国产精品福利自产拍在线观看| 辽宁熟女高潮狂叫视频| 国产大陆亚洲精品国产| 丰满岳乱妇在线观看中字无码| 日产日韩亚洲欧美综合下载| 97夜夜澡人人双人人人喊| 亚洲色成人中文字幕网站| 国产喷水福利在线视频| 蜜桃传媒av免费观看麻豆| 五月婷婷久久草丁香| 欧美日韩一区二区成人午夜电影 | 777米奇影视第四色| 成年女人看片永久免费视频| 美女视频黄频大全免费| 久久久久久国产精品免费免费男同| 午夜无码片在线观看影院y | 亚洲精品精华液一区二区|