在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. APIP Antibody

APIP Antibody

  • 中文名稱：
    APIP兔多克隆抗體
  • 貨號：
    CSB-PA555100
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA555100(APIP Antibody) at dilution 1/10, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 60 μg, Lane: Mouse heart tissue, Primary antibody: CSB-PA555100(APIP Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    APIP
  • 別名：
    Apaf1 Interacting Protein antibody; APAF1-interacting protein antibody; APIP antibody; APIP2 antibody; CG129 antibody; CGI 29 antibody; CGI29 antibody; dJ179L10.2 antibody; MMRP19 antibody; Monocyte/macrophage protein 19 antibody; MTNB_HUMAN antibody; MTRu 1 P dehydratase antibody; MTRu-1-P dehydratase antibody; Probable methylthioribulose 1 phosphate dehydratase antibody; Probable methylthioribulose-1-phosphate dehydratase antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human APIP
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:500-1:5000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death.
  • 基因功能參考文獻(xiàn)：
    1. Results suggest that APIP stimulates cell proliferation via ERBB3, acting in conjunction with ERBB2, in gastric cancer cells. PMID: 26942872
    2. APIP/MtnB functions as a cell death inhibitor independently of its MtnB enzyme activity for apoptosis induced by either hypoxia or etoposide, but dependently for caspase-1-induced pyroptosis PMID: 24367089
    3. these results confirm the involvement of APIP in the methionine salvage pathway, which plays a key role in many biological functions like cancer, apoptosis, microbial proliferation and inflammation. PMID: 23285211
    4. human APIP was overproduced in Escherichia coli, purified and crystallized. An X-ray diffraction data set was collected to 2.40 A resolution PMID: 23192037
    5. A polymorphism associated with reduced expression of a putative methionine salvage pathway dehydratase, apoptotic protease activating factor 1 (APAF1)-interacting protein (APIP), was associated with increased caspase-1-mediated cell death in Salmonella. PMID: 22837397
    6. The down-regulation of APIP and UACA expression suggests that the threshold to activate the apoptosome apparatus may be decreased in non-small cell lung cancer cells. PMID: 22407486
    7. APIP functions to inhibit muscle ischemic damage by binding to Apaf-1 in the Apaf-1/caspase-9 apoptosis pathway. PMID: 15262985

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm.
  • 蛋白家族：
    Aldolase class II family, MtnB subfamily
  • 組織特異性：
    Isoform 1 is ubiquitously expressed. Isoform 2 is expressed at lower levels and detected in heart, brain, pancreas, liver, placenta, skeletal muscle and kidney.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 17581

    OMIM: 612491

    KEGG: hsa:51074

    STRING: 9606.ENSP00000379133

    UniGene: Hs.447794



主站蜘蛛池模板： 精品国产免费观看久久久| 国产精品久久久久久久9999| 国产极品精品自在线| 亚洲成av大片大片在线播放| 国产成年女人毛片80s网站| 久久久久久成人毛片免费看| 人妻少妇偷人精品无码| 久久婷婷大香萑太香蕉av人| 欧美黑人xxxx性高清版| 乱人伦中文字幕成人网站在线| 久久无码人妻影院| 国产精品香蕉在线观看| 捆绑白丝粉色jk震动捧喷白浆| 亚洲性无码av在线dvd| 国产女人和拘做受视频免费| 欧美变态暴力牲交videos | 亚洲国产日韩一区三区| 中国女人内谢69xxxx免费视频| 艳z门照片无码av| 亚洲欧洲日产国码韩国| 色欲天天婬色婬香视频综合网| 日本无遮挡吸乳视频| 色偷偷噜噜噜亚洲男人 | 国产1卡二卡3卡四卡乱码视频| 国产裸体舞一区二区三区| 中文字幕乱码中文乱码51精品| 啊轻点内射在线视频| 无码免费h成年动漫在线观看| 久久午夜无码鲁丝片午夜精品| 免费国产va在线观看| 欧洲无线码免费一区| 92国产精品午夜福利免费| 国产精品www夜色视频| 亚洲欧美成人a∨观看| 日本一区二区无卡高清视频| 日本一区午夜艳熟免费| 国产熟妇高潮叫床视频播放| 女人被狂c到高潮视频网站| 黑人巨大av无码专区| 人妻无码久久久久久久久久久| 国产精品国产亚洲区艳妇糸列短篇|