在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. APIP Antibody

APIP Antibody

  • 中文名稱：
    APIP兔多克隆抗體
  • 貨號：
    CSB-PA555100
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA555100(APIP Antibody) at dilution 1/10, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 60 μg, Lane: Mouse heart tissue, Primary antibody: CSB-PA555100(APIP Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    APIP
  • 別名：
    Apaf1 Interacting Protein antibody; APAF1-interacting protein antibody; APIP antibody; APIP2 antibody; CG129 antibody; CGI 29 antibody; CGI29 antibody; dJ179L10.2 antibody; MMRP19 antibody; Monocyte/macrophage protein 19 antibody; MTNB_HUMAN antibody; MTRu 1 P dehydratase antibody; MTRu-1-P dehydratase antibody; Probable methylthioribulose 1 phosphate dehydratase antibody; Probable methylthioribulose-1-phosphate dehydratase antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human APIP
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:500-1:5000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death.
  • 基因功能參考文獻(xiàn)：
    1. Results suggest that APIP stimulates cell proliferation via ERBB3, acting in conjunction with ERBB2, in gastric cancer cells. PMID: 26942872
    2. APIP/MtnB functions as a cell death inhibitor independently of its MtnB enzyme activity for apoptosis induced by either hypoxia or etoposide, but dependently for caspase-1-induced pyroptosis PMID: 24367089
    3. these results confirm the involvement of APIP in the methionine salvage pathway, which plays a key role in many biological functions like cancer, apoptosis, microbial proliferation and inflammation. PMID: 23285211
    4. human APIP was overproduced in Escherichia coli, purified and crystallized. An X-ray diffraction data set was collected to 2.40 A resolution PMID: 23192037
    5. A polymorphism associated with reduced expression of a putative methionine salvage pathway dehydratase, apoptotic protease activating factor 1 (APAF1)-interacting protein (APIP), was associated with increased caspase-1-mediated cell death in Salmonella. PMID: 22837397
    6. The down-regulation of APIP and UACA expression suggests that the threshold to activate the apoptosome apparatus may be decreased in non-small cell lung cancer cells. PMID: 22407486
    7. APIP functions to inhibit muscle ischemic damage by binding to Apaf-1 in the Apaf-1/caspase-9 apoptosis pathway. PMID: 15262985

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm.
  • 蛋白家族：
    Aldolase class II family, MtnB subfamily
  • 組織特異性：
    Isoform 1 is ubiquitously expressed. Isoform 2 is expressed at lower levels and detected in heart, brain, pancreas, liver, placenta, skeletal muscle and kidney.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 17581

    OMIM: 612491

    KEGG: hsa:51074

    STRING: 9606.ENSP00000379133

    UniGene: Hs.447794



主站蜘蛛池模板： 久久久婷婷五月亚洲97号色| 秋霞午夜一区二区三区黄瓜视频| 99国产精品欧美一区二区三区| 亚洲国产av一区二区三区四区| 亚洲一区二区三区高清av| 精品久久久久久无码不卡| 欧美婷婷六月丁香综合| 在线中文字幕亚洲日韩2020| 国产美女精品一区二区三区 | 免费无码av片在线观看网址| 国产手机在线无码播放视频| 一个人看的日本hd免费| 国产亚洲欧美另类一区二区 | 丰满熟女人妻中文字幕免费 | 在线看片免费人成视频国产片| 国产精品无码天天爽视频| 无码国产精品一区二区免费式芒果| av天堂永久资源网亚洲高清| 女性自慰网站免费观看w| 国产精品 精品国内自产拍| 国产乱子伦精品无码专区| 亚洲国产成人久久综合碰| 日韩免费无码视频一区二区三区| 欧美精品色婷婷五月综合| 亚洲欧美日韩综合一区二区| 亚洲成a人片77777国产| 丰满少妇夜夜爽爽高潮水| 午夜免费男女aaaa片| 国产偷人妻精品一区| 动漫av永久无码精品每日更新 | 夜夜高潮天天爽欧美| 国产成人av大片大片在线播放| av在线亚洲欧洲日产一区二区| 日本人妻精品免费视频| 在线 | 一区二区三区四区| 免费观看激色视频网站| 久久久精品妇女99| 亚洲国产精品福利片在线观看| 精品一区精品二区制服| 电影内射视频免费观看| 国产又粗又硬又大爽黄老大爷|