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ANGPTL1 Antibody

  • 中文名稱:
    ANGPTL1兔多克隆抗體
  • 貨號:
    CSB-PA601738
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using CSB-PA601738(ANGPTL1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA601738(ANGPTL1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    ANGPTL1
  • 別名:
    ANG 3 antibody; ANG-3 antibody; ANG3 antibody; Angioarrestin antibody; Angiopoietin 3 antibody; Angiopoietin like 1 antibody; Angiopoietin like protein 1 antibody; Angiopoietin related protein 1 antibody; Angiopoietin Y1 antibody; Angiopoietin-3 antibody; Angiopoietin-like protein 1 antibody; Angiopoietin-related protein 1 antibody; ANGL1_HUMAN antibody; ANGPT3 antibody; ANGPTL1 antibody; AngY antibody; ARP1 antibody; dJ595C2.2 antibody; KIAA0351 antibody; UNQ162 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Fusion protein of Human ANGPTL1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 基因功能參考文獻:
    1. Low levels of ANGPTL1 is associated with colorectal cancer metastasis. PMID: 28606130
    2. ANGPTL1 inhibited angiogenesis by interacting with integrin alpha1beta1 receptor to suppress the downstreamJAK2-STAT3 signaling pathway. PMID: 28904065
    3. Aberrant expression of ANGPTL1 in cumulus cells is potentially associated with impaired oocyte developmental competence in polycystic ovary syndrome. PMID: 26829602
    4. Retinoic acid receptor beta and angiopoietin-like protein 1 are involved in the regulation of human androgen biosynthesis PMID: 25970467
    5. ANGPTL1 represses lung cancer cell motility by abrogating the expression of the epithelial mesenchymal transformation mediator SLUG. PMID: 23434592
    6. Inhibits experimental melanoma growth when transfected into murine cells. PMID: 15940350
    7. Immunohistochemical staining of Ang-1 was observed in smooth muscle cells, whereas Ang-2 was detected in endothelial cells, smooth muscle cells and macrophages. PMID: 18182823
    8. Overexpression of angiopoietin 1 and metalloproteinases may be the characteristic feature of endometrium with greater potential to transform into endometriotic lesions in the peritoneal cavity. PMID: 18644593

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  • 亞細胞定位:
    Secreted.
  • 組織特異性:
    Highly expressed in adrenal gland, placenta, thyroid gland, heart, skeletal muscle and small intestine. Weakly expressed in testis, ovary, colon, pancreas, kidney and stomach.
  • 數據庫鏈接:

    HGNC: 489

    OMIM: 603874

    KEGG: hsa:9068

    STRING: 9606.ENSP00000234816

    UniGene: Hs.591474



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