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ANGPTL1 Antibody

  • 中文名稱:
    ANGPTL1兔多克隆抗體
  • 貨號(hào):
    CSB-PA005586
  • 規(guī)格:
    ¥1090
  • 圖片:
    • Western Blot analysis of K562 cells using Angptl1 Polyclonal Antibody.
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    ANGPTL1
  • 別名:
    ANG 3 antibody; ANG-3 antibody; ANG3 antibody; Angioarrestin antibody; Angiopoietin 3 antibody; Angiopoietin like 1 antibody; Angiopoietin like protein 1 antibody; Angiopoietin related protein 1 antibody; Angiopoietin Y1 antibody; Angiopoietin-3 antibody; Angiopoietin-like protein 1 antibody; Angiopoietin-related protein 1 antibody; ANGL1_HUMAN antibody; ANGPT3 antibody; ANGPTL1 antibody; AngY antibody; ARP1 antibody; dJ595C2.2 antibody; KIAA0351 antibody; UNQ162 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human Angptl1.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    WB, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 基因功能參考文獻(xiàn):
    1. Low levels of ANGPTL1 is associated with colorectal cancer metastasis. PMID: 28606130
    2. ANGPTL1 inhibited angiogenesis by interacting with integrin alpha1beta1 receptor to suppress the downstreamJAK2-STAT3 signaling pathway. PMID: 28904065
    3. Aberrant expression of ANGPTL1 in cumulus cells is potentially associated with impaired oocyte developmental competence in polycystic ovary syndrome. PMID: 26829602
    4. Retinoic acid receptor beta and angiopoietin-like protein 1 are involved in the regulation of human androgen biosynthesis PMID: 25970467
    5. ANGPTL1 represses lung cancer cell motility by abrogating the expression of the epithelial mesenchymal transformation mediator SLUG. PMID: 23434592
    6. Inhibits experimental melanoma growth when transfected into murine cells. PMID: 15940350
    7. Immunohistochemical staining of Ang-1 was observed in smooth muscle cells, whereas Ang-2 was detected in endothelial cells, smooth muscle cells and macrophages. PMID: 18182823
    8. Overexpression of angiopoietin 1 and metalloproteinases may be the characteristic feature of endometrium with greater potential to transform into endometriotic lesions in the peritoneal cavity. PMID: 18644593

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  • 亞細(xì)胞定位:
    Secreted.
  • 組織特異性:
    Highly expressed in adrenal gland, placenta, thyroid gland, heart, skeletal muscle and small intestine. Weakly expressed in testis, ovary, colon, pancreas, kidney and stomach.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 489

    OMIM: 603874

    KEGG: hsa:9068

    STRING: 9606.ENSP00000234816

    UniGene: Hs.591474



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