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  4. AMT Antibody

AMT Antibody

  • 中文名稱：
    AMT兔多克隆抗體
  • 貨號：
    CSB-PA001684LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: A549 whole cell lysate, Mouse brain tissue
      All lanes: AMT antibody at 3.5µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 44, 38, 40, 42 kDa
      Observed band size: 44 kDa
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) AMT Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    AMT
  • 別名：
    Aminomethyltransferase (glycine cleavage system protein T) antibody; Aminomethyltransferase antibody; AMT antibody; GCE antibody; GCST antibody; GCST_HUMAN antibody; GCVT antibody; Glycine cleavage system T protein antibody; mitochondrial antibody; NKH antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Aminomethyltransferase, mitochondrial protein (180-260AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，AMT Antibody (CSB-PA001684LA01HU)，的標記方式是Non-conjugated。對于AMT Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA001684LB01HU AMT Antibody, HRP conjugated ELISA
    FITC CSB-PA001684LC01HU AMT Antibody, FITC conjugated
    Biotin CSB-PA001684LD01HU AMT Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    The glycine cleavage system catalyzes the degradation of glycine.
  • 基因功能參考文獻：
    1. The position and frequency of the breakpoint for CNVs correlated with intron size and presence of Alu elements. Missense mutations, most often recurring, were the most common type of disease-causing mutation in AMT PMID: 27362913
    2. Data indicate no mutation was found in glycine cleavage system protein-H (GCSH) and suggest that mutations in both glycine decarboxylase (GLDC) and aminomethyltransferase (AMT) are the main cause of glycine encephalopathy in Malaysian population. PMID: 25231368
    3. Two unique non-synonymous changes were identified in the AMT gene in patients with neural tube defects. PMID: 22171071
    4. x-ray crystallographic structure of human T-protein of glycine cleavage system PMID: 16051266
  • 相關疾病：
    Non-ketotic hyperglycinemia (NKH)
  • 亞細胞定位：
    Mitochondrion.
  • 蛋白家族：
    GcvT family
  • 數據庫鏈接：

    HGNC: 473

    OMIM: 238310

    KEGG: hsa:275

    STRING: 9606.ENSP00000273588

    UniGene: Hs.102



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