在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ADD2 Antibody

ADD2 Antibody

  • 中文名稱：
    ADD2兔多克隆抗體
  • 貨號(hào)：
    CSB-PA436650
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA436650(ADD2 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    ADD 2 antibody; ADD2 antibody; ADDB antibody; ADDB_HUMAN antibody; Adducin 2 (beta) antibody; Adducin2 antibody; Beta adducin antibody; Beta-adducin antibody; Erythrocyte adducin subunit beta antibody; OTTHUMP00000203378 antibody; OTTHUMP00000203908 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Fusion protein of Human ADD2
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    IHC 1:15-1:50
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to the erythrocyte membrane receptor SLC2A1/GLUT1 and may therefore provide a link between the spectrin cytoskeleton to the plasma membrane. Binds to calmodulin. Calmodulin binds preferentially to the beta subunit.
  • 基因功能參考文獻(xiàn)：
    1. betaadducin was demonstrated to have a critical role in neutrophil migration. PMID: 29901076
    2. Aberrant DNA methylation of ADD2 could be potential screening markers of colorectal cancer. PMID: 27493446
    3. Study evaluated effects of ADD genetic variability on cognitive functions in a sample of patients with schizophrenia, known to show a wide and heterogeneous neuropsychological deficit and found that ADD2 C1797T polymorphism showed diffuse effects on almost every cognitive domain. PMID: 26723519
    4. ADD2 and NCX1 variants influence the risk and the clinical features of systemic lupus erythematosus and lupus nephritis. PMID: 26045217
    5. Taken together, these results show that beta-adducin is a pivotal lipid raft-associated protein in PSGL-1-mediated neutrophil rolling on P-selectin. PMID: 25425738
    6. phosphorylation of beta-adducin by GSK3 promotes efficient neurite outgrowth in neurons. PMID: 21606488
    7. there was significant heterogeneity between Slavic and Italian subjects in the phenotype-genotype relationships with beta-adducin PMID: 14553963
    8. Expression of the hypertensive rat or human variant of adducin into normal renal epithelial cells recreates the hypertensive phenotype with higher Na+,K+-ATPase activity, mu2-subunit hyperphosphorylation, and impaired Na+,K+-ATPase endocytosis. PMID: 15528469
    9. Polymorphisms in the ADD2 and ADD3 genes taken alone were not associated with blood pressure and renin activity PMID: 15716695
    10. The very high levels of expression of ADD2 suggest that its promoter may be useful for directing erythroid-specific gene expression. PMID: 15963851
    11. beta-adducin is a downstream target of and regulated by the PTN/RPTPbeta/zeta signaling pathway PMID: 16105548
    12. Changes in intra-erythrocyte cations in ADD2 1797CC homozygous men might lead to osmotic fragility of erythrocytes, but to what extent they reflect systemic changes or are possibly involved in blood pressure regulation remains unknown. PMID: 17301826
    13. hypertension candidate gene variation may influence BP responses to specific antihypertensive drug therapies and measurement of genetic variation may assist in identifying subgroups of hypertensive patients benefiting from antihypertensive drug therapies PMID: 17854487

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族：
    Aldolase class II family, Adducin subfamily
  • 組織特異性：
    Expressed mainly in brain, spleen, kidney cortex and medulla, and heart. Also expressed in human umbilical vein endothelial cells, human vascular smooth muscle cells, kidney tubular cells and K-562 cell line.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 244

    OMIM: 102681

    KEGG: hsa:119

    STRING: 9606.ENSP00000264436

    UniGene: Hs.188528



主站蜘蛛池模板： 无遮挡1000部拍拍拍免费| 精品国产肉丝袜久久| 亚洲六月丁香六月婷婷| 领导边摸边吃奶边做爽在线观看| 欧美一夜爽爽爽爽爽爽| 亚洲日韩欧美一区久久久久我| 人妻中出无码一区二区三区| 少妇被又大又粗又爽毛片久久黑人 | av 日韩 人妻 黑人 综合 无码| 久久婷婷五月综合色中文字幕| 狠狠色丁香婷婷久久综合| 中文字幕人妻被公上司喝醉| 亚洲色精品88色婷婷七月丁香| 1000部拍拍拍18勿入免费视频下载| 香蕉久久一区二区三区啪啪| 国产精品无码2021在线观看| 国产在线乱子伦一区二区| 国产波霸爆乳一区二区| 无码人妻精品一区二区三| 国产亚洲精品福利视频在线观看| 蜜臀av999无码精品国产专区| 中国产xxxxa片在线观看| 国产精品亚洲一区二区三区| 亚洲aⅴ在线无码播放毛片一线天| 男人边吃奶边揉好爽免费视频| 97久久精品无码一区二区天美| 人人玩人人添人人澡超碰偷拍| 久久99精品国产99久久6| 国产精品久久久久久2021| 日本最大色倩网站www| 强迫大乳人妻中文字幕| 国产精品日本亚洲欧美| 国产成人无码区免费网站| 日韩在线一区二区三区免费视频| 韩国19禁主播深夜福利视频| 人妻少妇精品一区二区三区 | 老熟女重囗味hdxx70星空| 免费无码成人片| 国产一区二区三区在线视頻 | 国产片免费福利片永久| 国语自产偷拍精品视频偷|