在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ADD2 Antibody

  • 中文名稱:
    ADD2兔多克隆抗體
  • 貨號:
    CSB-PA001349GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    ADD 2 antibody; ADD2 antibody; ADDB antibody; ADDB_HUMAN antibody; Adducin 2 (beta) antibody; Adducin2 antibody; Beta adducin antibody; Beta-adducin antibody; Erythrocyte adducin subunit beta antibody; OTTHUMP00000203378 antibody; OTTHUMP00000203908 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human ADD2
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to the erythrocyte membrane receptor SLC2A1/GLUT1 and may therefore provide a link between the spectrin cytoskeleton to the plasma membrane. Binds to calmodulin. Calmodulin binds preferentially to the beta subunit.
  • 基因功能參考文獻:
    1. betaadducin was demonstrated to have a critical role in neutrophil migration. PMID: 29901076
    2. Aberrant DNA methylation of ADD2 could be potential screening markers of colorectal cancer. PMID: 27493446
    3. Study evaluated effects of ADD genetic variability on cognitive functions in a sample of patients with schizophrenia, known to show a wide and heterogeneous neuropsychological deficit and found that ADD2 C1797T polymorphism showed diffuse effects on almost every cognitive domain. PMID: 26723519
    4. ADD2 and NCX1 variants influence the risk and the clinical features of systemic lupus erythematosus and lupus nephritis. PMID: 26045217
    5. Taken together, these results show that beta-adducin is a pivotal lipid raft-associated protein in PSGL-1-mediated neutrophil rolling on P-selectin. PMID: 25425738
    6. phosphorylation of beta-adducin by GSK3 promotes efficient neurite outgrowth in neurons. PMID: 21606488
    7. there was significant heterogeneity between Slavic and Italian subjects in the phenotype-genotype relationships with beta-adducin PMID: 14553963
    8. Expression of the hypertensive rat or human variant of adducin into normal renal epithelial cells recreates the hypertensive phenotype with higher Na+,K+-ATPase activity, mu2-subunit hyperphosphorylation, and impaired Na+,K+-ATPase endocytosis. PMID: 15528469
    9. Polymorphisms in the ADD2 and ADD3 genes taken alone were not associated with blood pressure and renin activity PMID: 15716695
    10. The very high levels of expression of ADD2 suggest that its promoter may be useful for directing erythroid-specific gene expression. PMID: 15963851
    11. beta-adducin is a downstream target of and regulated by the PTN/RPTPbeta/zeta signaling pathway PMID: 16105548
    12. Changes in intra-erythrocyte cations in ADD2 1797CC homozygous men might lead to osmotic fragility of erythrocytes, but to what extent they reflect systemic changes or are possibly involved in blood pressure regulation remains unknown. PMID: 17301826
    13. hypertension candidate gene variation may influence BP responses to specific antihypertensive drug therapies and measurement of genetic variation may assist in identifying subgroups of hypertensive patients benefiting from antihypertensive drug therapies PMID: 17854487

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族:
    Aldolase class II family, Adducin subfamily
  • 組織特異性:
    Expressed mainly in brain, spleen, kidney cortex and medulla, and heart. Also expressed in human umbilical vein endothelial cells, human vascular smooth muscle cells, kidney tubular cells and K-562 cell line.
  • 數據庫鏈接:

    HGNC: 244

    OMIM: 102681

    KEGG: hsa:119

    STRING: 9606.ENSP00000264436

    UniGene: Hs.188528



主站蜘蛛池模板: 正在播放重口老熟女露脸| 乱人伦无码中文视频在线| 水蜜桃av无码| 欧美亚洲国产精品久久蜜芽| 综合激情亚洲丁香社区| 欧美日韩亚洲国产综合乱| 少妇富婆高级按摩出水高潮| 亚洲色丰满少妇高潮18p| 亚洲综合无码精品一区二区三区| 西西人体大胆午夜啪啪| 夜色约爱网站| 精品国产免费人成电影在线看| 国内自拍五区| 欧美成人免费一区二区| 香蕉成人伊视频在线观看| 中文字幕人妻熟女av| 亚洲在av极品无码| 国产色秀视频在线播放| 国产精欧美一区二区三区 | 国产精品情侣呻吟对白视频| 免费视频爱爱太爽了| 免费国产高清毛不卡片基地| 国产精品亚洲a∨天堂不卡| 天天躁日日躁狠狠躁视频2021| 精品夜夜澡人妻无码av蜜桃| 亚洲婷婷六月的婷婷| 中文字幕精品久久久久人妻红杏| 亚洲国产婷婷综合在线精品| 欧美丰满熟妇bbbbbb百度| 99久久精品免费看国产一区二区三区| 国产精品亚洲精品日韩已满十八小| 亚洲不卡1卡2卡三卡入口| 99久久国产综合精品成人影院| 欧美黑人添添高潮a片www| 男女啪啪做爰高潮无遮挡| 久久亚洲精品成人无码网站夜色| 国内午夜熟妇又乱又伦| 一区二区在线 | 欧洲| 1000部啪啪未满十八勿入下载| 国内熟女啪啪自拍| 欧洲美熟女乱又伦av|