在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ADCY10 Antibody, FITC conjugated

ADCY10 Antibody, FITC conjugated

  • 中文名稱：
    ADCY10兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA839393LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) ADCY10 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    ADCY10 antibody; SAC antibody; Adenylate cyclase type 10 antibody; EC 4.6.1.1 antibody; AH-related protein antibody; Adenylate cyclase homolog antibody; Germ cell soluble adenylyl cyclase antibody; hsAC antibody; sAC antibody; Testicular soluble adenylyl cyclase antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Adenylate cyclase type 10 protein (897-1136AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Catalyzes the formation of the signaling molecule cAMP. May function as sensor that mediates responses to changes in cellular bicarbonate and CO(2) levels. Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. Involved in ciliary beat regulation.
  • 基因功能參考文獻：
    1. results thus provide 1) novel insights into the communication between allosteric regulatory and active sites, 2) a novel mechanism for sAC inhibition, and 3) pharmacological compounds targeting this allosteric site and utilizing this mode of inhibition. PMID: 26961873
    2. The data support an important role for prostaglandin activation of sAC and PKA in H2O2-induced barrier disruption. PMID: 26857816
    3. Evaluation of soluble adenylyl cyclase expression using R21 antibody is a useful diagnostic adjunct in the evaluation of margins of LM during slow Mohs surgery. PMID: 24698940
    4. shows that in fibroblast cultures inhibition by KH7 of production in the mitochondrial matrix by soluble adenylyl cyclase PMID: 25409931
    5. Crystal structures of human ADCY10 catalytic domains in complex with nucleotides. PMID: 25040695
    6. Soluble adenylyl cyclase plays a role in the regulation of basal cCMP and cUMP. PMID: 24792377
    7. sAC is a regulator of gene expression involved in aldosterone signaling and an important regulator of endothelial stiffness. PMID: 24420537
    8. sAC is necessary for normal glucose-stimulated insulin secretion in vitro and in vivo. PMID: 24100033
    9. a haem-binding domain within the C-terminus of the human soluble adenylate cyclase PMID: 22775536
    10. Significant overexpression of soluble type 10 adenylyl cyclase (sAC), an alternative source of cAMP, was found in human prostate carcinoma. PMID: 23255611
    11. Regulation of anterior chamber drainage by bicarbonate-sensitive soluble adenylyl cyclase in the ciliary body. PMID: 21994938
    12. sAC may play a role in the pathogenesis of certain hyperproliferative skin disorders via modulation of gene expression PMID: 20130594
    13. Soluble adenylyl cyclase is localized to motile airway cilia and it contributes to the regulation of human airway ciliary beat frequency. PMID: 17591988
    14. These results show that bicarbonate-controlled sAC stimulation must be taken into account in cell physiology and that basal CFTR expression depends on an ionic parameter. PMID: 18209474
    15. a modest association between an ADCY10 polymorphism and the spinal areal BMD in premenopausal white women. PMID: 19093065

    顯示更多

    收起更多

  • 相關疾病：
    Hypercalciuria absorptive 2 (HCA2)
  • 亞細胞定位：
    Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Nucleus. Cell projection, cilium. Cytoplasm. Mitochondrion.
  • 蛋白家族：
    Adenylyl cyclase class-4/guanylyl cyclase family
  • 組織特異性：
    Detected in airway epithelial cells and testis (at protein level). Weakly expressed in multiple tissues. Expressed in brain, heart, kidney, liver, lung, pancreas, peripheral blood leukocytes, placenta, skeletal muscle, stomach, thymus, airway epithelial c
  • 數據庫鏈接：

    HGNC: 21285

    OMIM: 143870

    KEGG: hsa:55811

    STRING: 9606.ENSP00000356825

    UniGene: Hs.320892



主站蜘蛛池模板： 色一情一乱一伦一区二区三区日本 | 亚洲国产精品成人无码区| 中文人妻无码一区二区三区| 久久99热这里只有精品国产| 亚洲国产成人久久综合一区77| 小泽玛利亚一区二区在线观看| 国产高清成人免费视频在线观看| 国产蝌蚪视频一区二区三区| av天堂久久精品影音先锋| 亲近乱子伦免费视频| 国产剧情av麻豆香蕉精品| 亚洲精品亚洲人成在线观看| 女人与牲口性恔配视频免费| 欧美国产日本高清不卡| 乱色熟女综合一区二区三区| 日韩av无码成人无码免费| 日本少妇三级hd激情在线观看| 国产精品久久久一区二区三区| 欧美人做人爱a全程免费| 亚洲另类无码专区丝袜| 国产肉丝袜视频在线观看| 漂亮人妻被中出中文字幕| 午夜寂寞少妇aaa片毛片| 国产在线精品视频二区| 波多野结衣潮喷视频无码42| 欧美乱人伦人妻中文字幕| 天天爽夜夜爽夜夜爽| 四十如虎的丰满熟妇啪啪| 乱子伦国产对白在线播放| 中文无码一区二区三区在线观看 | 国产一区二区三区在线视頻 | 日韩av中文无码影院| 国产精品久久久久久久久久直播| 欧美国产国产综合视频| 久久香蕉国产线看观看手机| 无码大潮喷水在线观看| 久久久久99精品成人片直播| 欧美成人精品高清在线播放| 色五月丁香五月综合五月| 午夜三级a三级三点窝| 久久青青草原国产免费播放|