在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ADCY1 Antibody

ADCY1 Antibody

  • 中文名稱：
    ADCY1兔多克隆抗體
  • 貨號：
    CSB-PA001336GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    Adenylate cyclase 1; fetal brain; type I antibody; 3',5'-cyclic AMP synthetase antibody; AC1 antibody; Adcy1 antibody; ADCY1_HUMAN antibody; adenyl cyclase antibody; Adenylate cyclase 1 antibody; adenylate cyclase 1 (brain) antibody; Adenylate cyclase type 1 antibody; Adenylate cyclase type I antibody; Adenylyl cyclase 1 antibody; ATP pyrophosphate lyase antibody; ATP pyrophosphate-lyase 1 antibody; Brain adenylate cyclase 1 antibody; Ca(2+)/calmodulin-activated adenylyl cyclase antibody; deafness; autosomal recessive 44 antibody; DFNB44 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human ADCY1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    0.1M NaHCO3,0.1M Glycine, 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates responses to increased cellular Ca(2+)/calmodulin levels. May be involved in regulatory processes in the central nervous system. May play a role in memory and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina.
  • 基因功能參考文獻：
    1. data indicate that ST034307 is a selective small-molecule inhibitor of AC1 and suggest that selective AC1 inhibitors may be useful for managing pain. PMID: 28223412
    2. Data show that the adenylate cyclase (AC) pathway as genes relating to the antitumor activity of xanthohumol (XN) against tumor cells, and the pathway regulates various cellular functions via activating protein kinase A (PKA)-dependent phosphorylation. PMID: 28122154
    3. Maps to 7p14.1-q11.22 between D7S2209 and marker D7S2435, maximum Lod score 5 for D7S1818. PMID: 15583425
    4. STC1 interferes with CALCRL signaling during osteoblastogenesis via adenylate cyclase inhibition. PMID: 25591908
    5. AC1 catalytic activity can be adjusted by mediating calmodulin activation of AC1 by reversible methionine oxidation in calmodulin. PMID: 25462816
    6. Increased expression of AC1 in the forebrain leads to deficits in behavioral inhibition. PMID: 25568126
    7. AGS3 reduced D(2L)DR-mediated sensitization of AC1 and AC2. PMID: 23504261
    8. Compartmentalized AC1-CFTR association is responsible for Ca(2+)/cAMP cross-talk. PMID: 20554763
    9. Tissue transglutaminase directly regulates adenylyl cyclase resulting in enhanced cAMP-response element-binding protein (CREB) activation. PMID: 12743114
    10. Transgenic mice overexpressing type-1 adenylyl cyclase in the forebrain show elevated long-term potentiation (LTP), increased memory for object recognition and slower rates of extinction for contextual memory. PMID: 15133516
    11. Expression of sensitization of AC1 involves Galpha(s)-adenylyl cyclase interactions. PMID: 15361543
    12. These results suggest a possible role of APLP1 in regulation of alpha2A-adrenergic receptor trafficking. PMID: 16531006
    13. Fully differentiated human airway epithelial cells in culture are shown to express calcium-stimulated transmembrane adenylyl cyclase (tmAC) isoforms (types 1, 3, and 8) by reverse transcription polymerase chain reaction. PMID: 17586501
    14. Distinct mechanisms of regulation by Ca2+/calmodulin of type 1 and 8 adenylyl cyclases support their different physiological roles. PMID: 19029295
    15. Young transgenic mice overexpressing AC1 in the forebrain (AC1+ mice) have enhanced hippocampal long-term potentiation, superior memory for novel object recognition and more persistent remote contextual memory. PMID: 19726641

    顯示更多

    收起更多

  • 相關疾病：
    Deafness, autosomal recessive, 44 (DFNB44)
  • 亞細胞定位：
    Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasm. Membrane raft.
  • 蛋白家族：
    Adenylyl cyclase class-4/guanylyl cyclase family
  • 組織特異性：
    Detected in zona glomerulosa and zona fasciculata in the adrenal gland (at protein level). Brain, retina and adrenal medulla.
  • 數據庫鏈接：

    HGNC: 232

    OMIM: 103072

    KEGG: hsa:107

    STRING: 9606.ENSP00000297323

    UniGene: Hs.192215



主站蜘蛛池模板： 中文字幕丝袜精品久久| 国产精品对白交换视频| 亚洲最大成人网色| 国产成人欧美日本在线观看| 亚洲精品无码专区在线播放| 国产午夜手机精彩视频| 开心五月色婷婷综合开心网| 亚洲欧洲自拍拍偷精品 美利坚| 人成午夜大片免费视频| 国产伦精品一区二区三区妓女| 中文字幕在线亚洲精品| 亚洲美女精品免费视频| 欧美国产亚洲日韩在线二区| 美女视频黄频a美女大全| 人妻无码一区二区不卡无码av | 强制高潮18xxxxhd日韩| 无码人妻精品中文字幕免费东京热| 日本真人做爰免费的视频| 久久久久久99av无码免费网站| 亚洲精品成人福利网站app | 最近2019中文字幕大全第二页| 亚洲中文色欧另类欧美| 1313午夜精品理论片| 大地资源中文在线观看官网第二页| 男女性杂交内射女bbwxz| 亚洲综合另类小说色区| 真人啪啪高潮喷水呻吟无遮挡| 欧美性猛交aaaa片黑人| 久久亚洲一区二区三区四区五区| 国产成人亚洲日韩欧美| 极品少妇高潮到爽| 脱岳裙子从后面挺进去在线观看| 国产aⅴ精品一区二区三区尤物 | 国产精品高清网站| 男人和女人高潮免费网站| 四虎国产精品一区二区| 欧美人与动性xxxxx交性| 精品国产一区二区三区av 性色| 国产精品卡1卡2卡三卡四| 久久成人网站亚洲综合| 国产成人拍精品视频午夜网站|