在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ADCY1 Antibody, Biotin conjugated

ADCY1 Antibody, Biotin conjugated

  • 中文名稱：
    ADCY1兔多克隆抗體, Biotin偶聯(lián)
  • 貨號：
    CSB-PA600142LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) ADCY1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    Adenylate cyclase 1; fetal brain; type I antibody; 3',5'-cyclic AMP synthetase antibody; AC1 antibody; Adcy1 antibody; ADCY1_HUMAN antibody; adenyl cyclase antibody; Adenylate cyclase 1 antibody; adenylate cyclase 1 (brain) antibody; Adenylate cyclase type 1 antibody; Adenylate cyclase type I antibody; Adenylyl cyclase 1 antibody; ATP pyrophosphate lyase antibody; ATP pyrophosphate-lyase 1 antibody; Brain adenylate cyclase 1 antibody; Ca(2+)/calmodulin-activated adenylyl cyclase antibody; deafness; autosomal recessive 44 antibody; DFNB44 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Adenylate cyclase type 1 protein (416-610AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates responses to increased cellular Ca(2+)/calmodulin levels. May be involved in regulatory processes in the central nervous system. May play a role in memory and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina.
  • 基因功能參考文獻：
    1. data indicate that ST034307 is a selective small-molecule inhibitor of AC1 and suggest that selective AC1 inhibitors may be useful for managing pain. PMID: 28223412
    2. Data show that the adenylate cyclase (AC) pathway as genes relating to the antitumor activity of xanthohumol (XN) against tumor cells, and the pathway regulates various cellular functions via activating protein kinase A (PKA)-dependent phosphorylation. PMID: 28122154
    3. Maps to 7p14.1-q11.22 between D7S2209 and marker D7S2435, maximum Lod score 5 for D7S1818. PMID: 15583425
    4. STC1 interferes with CALCRL signaling during osteoblastogenesis via adenylate cyclase inhibition. PMID: 25591908
    5. AC1 catalytic activity can be adjusted by mediating calmodulin activation of AC1 by reversible methionine oxidation in calmodulin. PMID: 25462816
    6. Increased expression of AC1 in the forebrain leads to deficits in behavioral inhibition. PMID: 25568126
    7. AGS3 reduced D(2L)DR-mediated sensitization of AC1 and AC2. PMID: 23504261
    8. Compartmentalized AC1-CFTR association is responsible for Ca(2+)/cAMP cross-talk. PMID: 20554763
    9. Tissue transglutaminase directly regulates adenylyl cyclase resulting in enhanced cAMP-response element-binding protein (CREB) activation. PMID: 12743114
    10. Transgenic mice overexpressing type-1 adenylyl cyclase in the forebrain show elevated long-term potentiation (LTP), increased memory for object recognition and slower rates of extinction for contextual memory. PMID: 15133516
    11. Expression of sensitization of AC1 involves Galpha(s)-adenylyl cyclase interactions. PMID: 15361543
    12. These results suggest a possible role of APLP1 in regulation of alpha2A-adrenergic receptor trafficking. PMID: 16531006
    13. Fully differentiated human airway epithelial cells in culture are shown to express calcium-stimulated transmembrane adenylyl cyclase (tmAC) isoforms (types 1, 3, and 8) by reverse transcription polymerase chain reaction. PMID: 17586501
    14. Distinct mechanisms of regulation by Ca2+/calmodulin of type 1 and 8 adenylyl cyclases support their different physiological roles. PMID: 19029295
    15. Young transgenic mice overexpressing AC1 in the forebrain (AC1+ mice) have enhanced hippocampal long-term potentiation, superior memory for novel object recognition and more persistent remote contextual memory. PMID: 19726641

    顯示更多

    收起更多

  • 相關(guān)疾?。?/div>
    Deafness, autosomal recessive, 44 (DFNB44)
  • 亞細胞定位：
    Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasm. Membrane raft.
  • 蛋白家族：
    Adenylyl cyclase class-4/guanylyl cyclase family
  • 組織特異性：
    Detected in zona glomerulosa and zona fasciculata in the adrenal gland (at protein level). Brain, retina and adrenal medulla.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 232

    OMIM: 103072

    KEGG: hsa:107

    STRING: 9606.ENSP00000297323

    UniGene: Hs.192215



主站蜘蛛池模板： 亚洲精品无码久久久久av麻豆| 国产va免费精品高清在线| 欧美乱妇高清无乱码免费| 黄网站色视频免费国产| 99re8精品视频热线观看| 男人狂躁进女人下面免费视频| 无码人妻一区二区三区av| 国产成人精品优优av| 人妻aⅴ无码一区二区三区| 亚洲伊人成综合人影院青青青| 欧美激烈精交gif动态图| 一本加勒比hezyo无码专区| 国产精品久久人妻无码网站一区 | 6699嫩草久久久精品影院| 性按摩xxxx在线观看| 久久综合给综合给久久| 亚洲中文字幕第一页在线| 国产又粗又猛又爽又黄的视频在线观看动漫| 亚洲国产成人综合精品| 久久人人97超碰国产亚洲人| 免费人成在线观看网站品爱网| 人妻丰满熟妇av无码区| 国产精品成人免费一区久久羞羞| 人妻少妇乱子伦无码专区| 久久无码喷吹高潮播放不卡| 大白肥妇bbvbbw高潮| 免费的很黄很污的视频| 欧美婷婷丁香五月社区| 狠狠色噜噜狠狠狠888米奇| 国产男女性潮高清免费网站| _97夜夜澡人人爽人人喊_欧美| 亚洲手机在线人成网站| 天堂无码人妻精品av一区| 特级av毛片免费观看| 老色鬼永久视频网站| 亚欧日韩欧美网站在线看| 午夜理理伦电影a片无码| 日韩 无码 偷拍 中文字幕| 伊人伊成久久人综合网996| 成人乱码一区二区三区av| 国产欧美另类久久精品蜜芽|