在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ACTL6B Antibody

  • 中文名稱:
    ACTL6B兔多克隆抗體
  • 貨號:
    CSB-PA001237ESR2HU
  • 規格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: Actin-like protein 6B antibody at 3μg/ml
      Lane 1: Hela whole cell lysate
      Lane 2: U251 whole cell lysate
      Lane 3: HepG2 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 47 kDa
      Observed band size: 47 kDa
    • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA001237ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA001237ESR2HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) ACTL6B Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    ACTL6B
  • 別名:
    53 kDa BRG1 associated factor B antibody; 53 kDa BRG1-associated factor B antibody; ACL 6B antibody; ACL6B antibody; ACL6B_HUMAN antibody; Actin like 6 antibody; Actin like protein 6B antibody; Actin like protein6B antibody; Actin related protein antibody; Actin related protein Baf53b antibody; actin-like 6B antibody; Actin-like protein 6B antibody; Actin-related protein Baf53b antibody; Actl 6 antibody; ACTL 6B antibody; Actl6 antibody; ACTL6 B antibody; Actl6b antibody; Arp Na antibody; ArpN a antibody; ArpN alpha antibody; ArpNa antibody; ArpNalpha antibody; Baf 53b antibody; BAF53B antibody; BRG1-associated factor 53B antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Actin-like protein 6B protein (1-280AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:200-1:1000
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex), as such plays a role in remodeling mononucleosomes in an ATP-dependent fashion, and is required for postmitotic neural development and dendritic outgrowth. During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth. ACTL6B/BAF53B is not essential for assembly of the nBAF complex but is required for targeting the complex and CREST to the promoter of genes essential for dendritic growth. Essential for neuronal maturation and dendrite development.
  • 基因功能參考文獻:
    1. Missense Mutation in ACTL6B gene is associated with Neurodevelopmental Disorders. PMID: 28867141
    2. we identified BAF53b as a neuron-specific subunit of the chromatin remodeling BAF complexes. PMID: 26077106
    3. Data suggest that SWI/SNF complexes containing ArpN alpha might regulate certain genes involved in brain development and/or its function differently from SWI/SNF complexes containing ArpN beta/BAF53. PMID: 12565893
  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    Actin family
  • 數據庫鏈接:

    HGNC: 160

    OMIM: 612458

    KEGG: hsa:51412

    STRING: 9606.ENSP00000160382

    UniGene: Hs.259831



主站蜘蛛池模板: 国产 | 欧洲野花视频欧洲1| 精品人妻伦一二三区久久| 天天操夜夜操| 在线观看国产日韩亚洲中| 久青草国产在视频在线观看| 国产黑色丝袜在线视频| 欧美日韩国产免费一区二区三区 | 乱人伦视频中文字幕| 国内熟妇人妻色无码视频在线| 欧美精品一国产成人综合久久 | 又色又爽又黄的gif动态图| 99r在线精品视频在线播放| 国产高清在线精品二区| 日本成aⅴ人片日本伦| 国产精品丝袜肉丝出水| 狠狠色噜噜狠狠狠狠米奇777| 亚洲日韩欧美在线成人| 人妻体内射精一区二区三区 | 久久精品一区二区免费播放| 国产极品美女高潮无套在线观看| 国产xxxx做受性欧美88| 亚洲国产精品无码7777一线| 国产成人一区二区三区app| 国産精品久久久久久久| 亚洲伊人久久大香线蕉综合图片| 亚洲精品国产一区二区精华| 中国老熟女重囗味hdxx| 日韩va中文字幕无码电影| 亚洲夜色噜噜av在线观看| 久久99亚洲精品久久69| 久久综合久久综合九色| 日韩人妻无码一区二区三区久久99 | 精品一卡2卡3卡4卡新区在线| 插一插射一射视频| 亚洲欧美日韩精品色xxx| 日韩欧美群交p内射捆绑| 强奷妇系列中文字幕| 亚洲а∨天堂久久精品2021| 性强烈的欧美三级视频| 日日日日做夜夜夜夜无码 | av无码精品一区二区三区宅噜噜|