在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ACTG1 Antibody

  • 中文名稱:
    ACTG1兔多克隆抗體
  • 貨號:
    CSB-PA218620
  • 規格:
    ¥1100
  • 圖片:
    • Gel: 10+12%SDS-PAGE, Lysate: 40 μg, Lane: Human lymphoma tissue, Primary antibody: CSB-PA218620(ACTG1 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 second
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    ACT antibody; ACTB antibody; ACTG antibody; ACTG_HUMAN antibody; actg1 antibody; Actin antibody; Actin; cytoplasmic 2 antibody; Actin; gamma 1 antibody; Actin; gamma 1 propeptide antibody; Actin; gamma antibody; BRWS2 antibody; cytoplasmic 2 antibody; Cytoskeletal gamma actin antibody; Deafness; autosomal dominant 20 antibody; Deafness; autosomal dominant 26 antibody; DFNA20 antibody; DFNA26 antibody; epididymis luminal protein 176 antibody; Gamma-actin antibody; HEL-176 antibody; N-terminally processed antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Fusion protein of Human ACTG1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
  • 基因功能參考文獻:
    1. A novel actin gamma 1 (ACTG1) de novo mutation is identified in two sporadic, juvenile, Chinese non-syndromic hearing loss (NSHL) cases using targeted high-throughput sequencing. PMID: 29357087
    2. Results identified ACTG1 with significant high expression in skin cancer tissue and suggested that ACTG1 can regulate the cell proliferation and migration through ROCK signaling pathway. PMID: 28727228
    3. a novel heterozygous missense mutation P32S in the ACTG1 gene was identified in a small family with autosomal dominant nonsyndromic hearing loss. The present findings expand our understanding of the phenotypes associated with ACTG1. Specifically, the results of the present study emphasized that mutations in ACTG1 result in a diverse spectrum of onset ages, including congenital in addition to post-lingual onset. PMID: 29620237
    4. Data reports a recurrent de novo mutation in ACTG1 causes isolated ocular coloboma PMID: 28493397
    5. We have identified a three-generation pedigree segregating a novel mutation in the ACTG1 gene that causes Baraitser-Winter Syndrome with extremely variable expressivity, leading to an initial diagnosis of isolated AD hearing loss in two members. PMID: 27096712
    6. we expand the clinical spectrum of the ACTG1-associated Baraitser-Winter cerebrofrontofacial syndrome demonstrating the mild end of the facial and brain manifestations. PMID: 27240540
    7. Data indicate that F-actin is significantly elevated in septic shock, and F-actin and the F:G-actin ratio are potential biomarkers for the diagnosis of septic shock. PMID: 26754286
    8. a novel mutation in ACTG1 was found to be co-segregated with hearing loss and the genetic cause of autosomal dominant nonsyndromic hearing impairment in a Chinese family PMID: 26832775
    9. Three unrelated cases of rare ACTG1 variants in fetal microlissencephaly have been described. PMID: 26188271
    10. In this study we sought to clarify the detailed mutational spectrum, clinical features, and genotype-phenotype correlations for ACTG1 gene associated autosomal dominant sensorineural hearing loss PMID: 25792668
    11. The data, for the first time, link ASAP3 with ACTG1 in the regulation of cytoskeletal maintenance and cell motility PMID: 24284654
    12. The actin/MKL1 signalling pathway influences cell growth and gene expression through large-scale chromatin reorganization and histone post-translational modifications. PMID: 24762104
    13. the novel variant p.M305T in ACTG1 (DFNA20/26) was selected as a disease-causing variant. PMID: 23506231
    14. These results showed the biphasic F-actin dynamics in herpes simplex virus 1 neuronal infection and confirmed the association of F-actin with the changes in the expression and activity of cofilin 1. PMID: 22623803
    15. knockdown of gamma-actin significantly reduced speed of motility and severely affected the cell's ability to explore, which was, in part, due to a loss of cell polarity PMID: 21908715
    16. Cytoplasmic G-actin concentration is a critical parameter for determining the extent of stimulus-induced G-actin assembly and cell extension. PMID: 21502360
    17. actin participates in transcription elongation by recruiting Cdk9,a catalytic subunit of P-TEFb, for phosphorylation of the Pol II C-terminal domain, and the actin-Cdk9 interaction promotes chromatin remodeling PMID: 21378166
    18. RNA polymerase II accumulates in the promoter-proximal region of the dihydrofolate reductase and gamma-actin genes. PMID: 12612070
    19. the first description of a mutation in cytoskeletal, or nonmuscle, actin; with an autosomal dominant, progressive, sensorineural hearing loss phenotype PMID: 13680526
    20. A missense mutation in the gamma actin 1 gene causes autosomal dominant hearing loss. PMID: 14684684
    21. Our data are consistent with the idea that DP assembles into nascent junctions from both diffusible and particulate pools in a temporally overlapping series of events triggered by cell-cell contact and regulated by actin and DP-IF interactions. PMID: 16365169
    22. Espins do not activate the Arp2/3 complex in vitro, and bundle assembly is not indicative of in-vitro nucleation activity.Our results suggest a novel way to build actin bundles at specific sites in cells. PMID: 16569662
    23. A major factor in the deafness caused by gamma-actin mutations is an altered ability of the actin filaments to be properly regulated by actin-binding proteins rather than an inability to polymerize. PMID: 16690605
    24. the present results do not indicate that mutations in ACTG1 are a frequent cause of autosomal-dominant postlingual sensorineural hearing impairment in Norway nor Denmark. PMID: 16773128
    25. actin and vimentin filaments can interact directly through the tail domain of vimentin PMID: 16901892
    26. During cell membrane blebbing actin recruitment is involved in cortex assembly. PMID: 17088428
    27. In both AA and AL renal amyloidosis groups there were significant positive correlations between immunostaining of TGFbeta-1 and alpha-SMA. PMID: 17285762
    28. IQGAP1 regulates Salmonella invasion through interactions with actin, Rac1, and Cdc42 PMID: 17693642
    29. In this report we have used mutagenesis of the Talin1 I/LWEQ module to show that the amino acids responsible for dimerization are necessary for F-actin binding, stabilization and cross-linking of actin filaments, and focal adhesion targeting. PMID: 17722883
    30. analysis of the structural basis of profilin-actin complexes during filament elongation by Ena/VASP PMID: 17914456
    31. In this study, a novel missense mutation (c.364A>G; p.I122V) co-segregated with the affected individuals in the family and did not exist in the unaffected family members and 150 unrelated normal controls. PMID: 18804074
    32. Both RPEL peptides of the MAL protein bind to the G-actin hydrophobic cleft and to subdomain 3. PMID: 19008859
    33. Two novel ACTG1 missense mutations are associated with DFNA20/26 hearing impairment. PMID: 19477959
    34. audiometric phenotype of the Dutch DFNA20/26 family with a novel mutation in ACTG1 was largely consistent with previous reports on DFNA20/26. All suffered from hearing loss.This is the first known DFNA20/26 family that has experienced tinnitus. PMID: 19548389

    顯示更多

    收起更多

  • 相關疾病:
    Deafness, autosomal dominant, 20 (DFNA20); Baraitser-Winter syndrome 2 (BRWS2)
  • 亞細胞定位:
    Cytoplasm, cytoskeleton.
  • 蛋白家族:
    Actin family
  • 數據庫鏈接:

    HGNC: 144

    OMIM: 102560

    KEGG: hsa:71

    STRING: 9606.ENSP00000331514

    UniGene: Hs.514581



主站蜘蛛池模板: 亚洲色无码专区在线观看| 亚洲婷婷六月的婷婷| 最近免费中文字幕大全免费版视频| 国产初高中生粉嫩无套第一次| 天堂va欧美ⅴa亚洲va| 99精品人妻少妇一区二区| 隔壁人妻偷人bd中字| 中文综合在线观| 色噜噜狠狼综合在线| 伊人精品成人久久综合| 亚洲国产无套无码av电影| 麻花传媒在线mv免费观看视频| 欧美成人免费全部| 亚洲熟妇av午夜无码不卡| 伊人狼人大焦香久久网| 粗大的内捧猛烈进出视频| 久久精品国产99精品国产2021| 香港三级日本三级a视频 | 国产成人mv视频在线观看| 欧美综合区自拍亚洲综合绿色| 大肉大捧一进一出好爽视频mba | 亚洲日韩在线a视频在线观看| 一区二区三区国产精华液| 国产精品成人免费视频网站京东| 波多野结衣美乳人妻hd电影欧美 | 久久精品国产色蜜蜜麻豆| 精品国产一区二区三区四区在线看| 国产精品禁忌a片特黄a片| 无码国产色欲xxxxx视频| 欧美国产成人精品一区二区三区| av网站免费线看精品| 国产午睡沙发被弄醒完整版| 国产乱码二卡3卡四卡| 久久久精品波多野结衣| 国产成人精品.视频| 永久免费无码av在线网站| 国产精品福利一区二区| 四虎影视成人永久免费观看视频| 永久免费的av在线电影网| 伊人久久大香线蕉无码不卡| 国产日韩欧美|