在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ABCB7 Antibody

ABCB7 Antibody

  • 中文名稱：
    ABCB7兔多克隆抗體
  • 貨號(hào)：
    CSB-PA001053LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA001053LA01HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) ABCB7 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ABCB7
  • 別名：
    ABC transporter 7 protein antibody; ABC7 antibody; Abcb7 antibody; ABCB7_HUMAN antibody; ASAT antibody; Atm1p antibody; ATP binding cassette 7 antibody; ATP binding cassette sub family B (MDR/TAP) member 7 antibody; ATP binding cassette sub family B member 7 antibody; ATP binding cassette sub family B member 7 mitochondrial antibody; ATP binding cassette transporter 7 antibody; ATP-binding cassette sub-family B member 7 antibody; ATP-binding cassette transporter 7 antibody; EST140535 antibody; MDR7 antibody; mitochondrial antibody; Multidrug resistance protein 7 antibody; P-glycoprotein 7 antibody; PGP7 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human ATP-binding cassette sub-family B member 7, mitochondrial protein (23-140AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，ABCB7 Antibody (CSB-PA001053LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于ABCB7 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA001053LB01HU ABCB7 Antibody, HRP conjugated ELISA
    FITC CSB-PA001053LC01HU ABCB7 Antibody, FITC conjugated
    Biotin CSB-PA001053LD01HU ABCB7 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Exports glutathione-coordinated iron-sulfur clusters such as [2Fe-2S]-(GS)4 cluster from the mitochondria to the cytosol in an ATP-dependent manner allowing the assembly of the cytosolic iron-sulfur (Fe/S) cluster-containing proteins and participates in iron homeostasis. Moreover, through a functional complex formed of ABCB7, FECH and ABCB10, also plays a role in the cellular iron homeostasis, mitochondrial function and heme biosynthesis. In cardiomyocytes, regulates cellular iron homeostasis and cellular reactive oxygen species (ROS) levels through its interaction with COX4I1. May also play a role in hematopoiesis.
  • 基因功能參考文獻(xiàn)：
    1. data support a model in which cycloheximide -induced downregulation of the iron exporter ABCB7 mRNA transcript resulting from aberrant splicing caused by mutant SF3B1 underlies the increased mitochondrial iron accumulation found in MDS patients with ring sideroblasts PMID: 27211273
    2. A missense mutation in the ABCB7 is a major causative factor of the cerebellar hypoplasia/atrophy found in affected individuals of a Buryat family who had no evidence of sideroblastic anemia. PMID: 26242992
    3. findings support that ABCB7 is implicated in the phenotype of acquired RARS and suggest a relation between SF3B1 mutations and ABCB7 downregulation PMID: 23070040
    4. We describe a fourth family with X-linked sideroblastic anemia and ataxia and a novel mutation in the ABCB7 gene PMID: 22398176
    5. loss of the ABCB7 gene may be a pathogenetic factor underlying mitochondrial iron accumulation in RARS patients with idicXq13. PMID: 21380928
    6. ABCB7 may have a role in refractory anemia with ring sideroblasts PMID: 18398482

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Anemia, sideroblastic, spinocerebellar ataxia (ASAT)
  • 亞細(xì)胞定位：
    Mitochondrion inner membrane; Multi-pass membrane protein.
  • 蛋白家族：
    ABC transporter superfamily, ABCB family, Heavy Metal importer (TC 3.A.1.210) subfamily
  • 數(shù)據(jù)庫鏈接：

    HGNC: 48

    OMIM: 300135

    KEGG: hsa:22

    STRING: 9606.ENSP00000253577

    UniGene: Hs.370480



主站蜘蛛池模板： 国产成人综合色视频精品| 欧洲亚洲国产成人综合色婷婷| 国精品无码一区二区三区左线| 天堂√在线中文最新版| 呻吟国产av久久一区二区| 波多野结衣在线精品视频| 18无码粉嫩小泬无套在线观看| 电影久久久久久| 亚洲天堂2017无码中文| 99国产精品久久久久久久日本竹 | 国产精品99爱免费视频| 人妻中文字幕无码系列| 久久国产精品99国产精| 中文字幕资源网| 国产精品无码一区二区牛牛| 亚洲欧洲日本无在线码| 无码国产色欲xxxxx视频| 久久99日韩国产精品久久99| 久久久久香蕉国产线看观看伊 | 亚洲精品v天堂中文字幕| 欧美三级韩国三级日本三斤 | 亚洲精品一品区二品区三品区 | 国产精品久久久久久久妇| 狠狠的干性视频| 国产男女猛烈无遮挡免费视频网站 | 久久久久亚洲精品成人网| 免费国产成人午夜福利电影| 久久久久se色偷偷亚洲精品av| 无码人妻丝袜在线视频| 久久经精品久久精品免费观看| 久久69精品久久久久久hb| 思思99re6国产在线播放| 色狠狠色噜噜av天堂一区| 粉嫩av国产一区二区三区| 亚洲色中文字幕无码av| 精品一卡2卡三卡4卡乱码精品视频| 国内精品久久久久影视老司机| 精品人妻大屁股白浆无码| 美女内射毛片在线看3d| 欧美亚洲日本日韩在线| 亚洲精品无码不卡在线播放he|