在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ABCB7 Antibody, HRP conjugated

ABCB7 Antibody, HRP conjugated

  • 中文名稱：
    ABCB7兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA001053LB01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) ABCB7 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ABCB7
  • 別名：
    ABC transporter 7 protein antibody; ABC7 antibody; Abcb7 antibody; ABCB7_HUMAN antibody; ASAT antibody; Atm1p antibody; ATP binding cassette 7 antibody; ATP binding cassette sub family B (MDR/TAP) member 7 antibody; ATP binding cassette sub family B member 7 antibody; ATP binding cassette sub family B member 7 mitochondrial antibody; ATP binding cassette transporter 7 antibody; ATP-binding cassette sub-family B member 7 antibody; ATP-binding cassette transporter 7 antibody; EST140535 antibody; MDR7 antibody; mitochondrial antibody; Multidrug resistance protein 7 antibody; P-glycoprotein 7 antibody; PGP7 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human ATP-binding cassette sub-family B member 7, mitochondrial protein (23-140AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Exports glutathione-coordinated iron-sulfur clusters such as [2Fe-2S]-(GS)4 cluster from the mitochondria to the cytosol in an ATP-dependent manner allowing the assembly of the cytosolic iron-sulfur (Fe/S) cluster-containing proteins and participates in iron homeostasis. Moreover, through a functional complex formed of ABCB7, FECH and ABCB10, also plays a role in the cellular iron homeostasis, mitochondrial function and heme biosynthesis. In cardiomyocytes, regulates cellular iron homeostasis and cellular reactive oxygen species (ROS) levels through its interaction with COX4I1. May also play a role in hematopoiesis.
  • 基因功能參考文獻：
    1. data support a model in which cycloheximide -induced downregulation of the iron exporter ABCB7 mRNA transcript resulting from aberrant splicing caused by mutant SF3B1 underlies the increased mitochondrial iron accumulation found in MDS patients with ring sideroblasts PMID: 27211273
    2. A missense mutation in the ABCB7 is a major causative factor of the cerebellar hypoplasia/atrophy found in affected individuals of a Buryat family who had no evidence of sideroblastic anemia. PMID: 26242992
    3. findings support that ABCB7 is implicated in the phenotype of acquired RARS and suggest a relation between SF3B1 mutations and ABCB7 downregulation PMID: 23070040
    4. We describe a fourth family with X-linked sideroblastic anemia and ataxia and a novel mutation in the ABCB7 gene PMID: 22398176
    5. loss of the ABCB7 gene may be a pathogenetic factor underlying mitochondrial iron accumulation in RARS patients with idicXq13. PMID: 21380928
    6. ABCB7 may have a role in refractory anemia with ring sideroblasts PMID: 18398482

    顯示更多

    收起更多

  • 相關疾病：
    Anemia, sideroblastic, spinocerebellar ataxia (ASAT)
  • 亞細胞定位：
    Mitochondrion inner membrane; Multi-pass membrane protein.
  • 蛋白家族：
    ABC transporter superfamily, ABCB family, Heavy Metal importer (TC 3.A.1.210) subfamily
  • 數據庫鏈接：

    HGNC: 48

    OMIM: 300135

    KEGG: hsa:22

    STRING: 9606.ENSP00000253577

    UniGene: Hs.370480



主站蜘蛛池模板： 欧美拍拍视频免费大全| 少妇厨房愉情理9仑片视频| 天堂在线中文网www| 99久久久无码国产精品动漫| 青青青草国产线观| 成人精品免费视频在线观看| 东京热人妻丝袜av无码| 欧美黑人大战白嫩在线| 日本强好片久久久久久aaa| 国产三区在线成人av| 免费h动漫无码网站| 2021年精品国产福利在线| 特级无码毛片免费视频播放▽| 久无码久无码av无码| 免费国产黄网站在线观看视频| 国产高清乱码又大又圆| 少妇人妻中文字幕污| 老头把我添高潮了a片| 婷婷成人综合激情在线视频播放 | 久久久久久亚洲综合影院| www成人国产高清内射| 日本高清aⅴ毛片免费| 久久亚洲精品成人av无码网站 | 精品服丝袜无码视频一区| 久久精品国产成人午夜福利| 国产欧美亚洲精品a| 国内精品伊人久久久久777| 国产激情大臿免费视频| 国产又粗又黄又爽的大片| 亚洲国产欧美在线人成最新| 国产美女精品一区二区三区 | 国产午夜成人久久无码一区二区| 欧美人与动牲交xxxxbbbb| 亚洲 综合 校园 欧美 制服| 久久久精品人妻一区二区三区gv | 色婷婷欧美在线播放内射| 欧美两根一起进3p做受视频| 国产免费人成在线视频网站| 久久婷婷是五月综合色| 337p大胆啪啪私拍人体| 女邻居的大乳中文字幕|