在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ABAT Antibody

  • 中文名稱:
    ABAT兔多克隆抗體
  • 貨號:
    CSB-PA001032GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    ABAT
  • 別名:
    (S) 3 amino 2 methylpropionate transaminase antibody; (S)-3-amino-2-methylpropionate transaminase antibody; 4 aminobutyrate aminotransferase antibody; 4 aminobutyrate aminotransferase; mitochondrial antibody; 4-aminobutyrate aminotransferase antibody; ABAT antibody; FLJ17813 antibody; FLJ30272 antibody; GABA aminotransferase antibody; GABA AT antibody; GABA T antibody; GABA transaminase antibody; GABA transferase antibody; GABA-AT antibody; GABA-T antibody; GABAT antibody; GABT_HUMAN antibody; Gamma amino N butyrate transaminase antibody; Gamma-amino-N-butyrate transaminase antibody; hCG1984265 antibody; L AIBAT antibody; L-AIBAT antibody; LAIBAT antibody; mitochondrial antibody; NPD009 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human ABAT
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine.
  • 基因功能參考文獻:
    1. This study utilized ER+ IBC to identify a metagene including ABAT and STC2 as predictive biomarkers for endocrine therapy resistance. PMID: 25771305
    2. A-to-G transition at nucleotide 754 of the human ABAT gene identified in lymphoblast cDNA (c.754A>G) results in substitution of an invariant arginine at amino acid 220 by lysine (p.Arg220Lys). This point mutation results in destabilization of the binding of pyridoxal-5'-phosphate to GABA-transaminase (required for transamination of GABA to succinic semialdehyde) and thus results in GABA-transaminase deficiency. PMID: 25485164
    3. Findings point to a possible role of ABAT gene-regulated GABA catabolism for an altered processing of somatosensory stimuli as a potential vulnerability marker for affective disorders. PMID: 22225676
    4. direct involvement of ABAT in pathways affecting lower esophageal sphincter (LES) control in gastro esophageal reflux disease PMID: 21552517
    5. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 20659789
    6. excessive prenatal GABA exposure in the central nervous system (CNS) is responsible for the clinical manifestations of GABA transaminase deficiency [case report] PMID: 20052547
    7. Marked differences in platelet uptake of GABA and activity of catabolic enzyme GABA-T between patients with generalized and localization-related epileptic syndromes. May indicate an impairment in function of brain GABAergic systems. PMID: 12694932
    8. results suggest that the Cys321 residue is essential for the catalytic function of GABAT, and that it is involved in the formation of a disulfide link between two monomers of human brain GABAT PMID: 15528998
    9. lysine 357 is essential for catalytic function of brain GABA transaminase, and is involved in binding PLP at the active site PMID: 15650327
    10. Analysis of the autistic disorder susceptibility locus suggests an association on chromosome 16p between GRIN2A and ABAT. PMID: 15830322

    顯示更多

    收起更多

  • 相關疾病:
    GABA transaminase deficiency (GABATD)
  • 亞細胞定位:
    Mitochondrion matrix.
  • 蛋白家族:
    Class-III pyridoxal-phosphate-dependent aminotransferase family
  • 組織特異性:
    Liver > pancreas > brain > kidney > heart > placenta.
  • 數據庫鏈接:

    HGNC: 23

    OMIM: 137150

    KEGG: hsa:18

    STRING: 9606.ENSP00000268251

    UniGene: Hs.336768



主站蜘蛛池模板: 中文字幕在线影视| 国产蜜芽尤物在线一区| 少妇性荡欲视频| 亚洲欧美日韩综合俺去了| 美女脱了内裤张开腿让男人桶网站| 亚洲综合色自拍一区| 国产男女无遮挡猛进猛出| 久久久久久妓女精品影院| 亚洲漂亮少妇毛茸茸| 国产精品久久久久一区二区三区 | 狠狠88综合久久久久综合网| 日日躁夜夜躁狠狠躁| 国产日产欧产精品精品app| 熟女人妻av完整一区二区三区| 狠狠躁天天躁中文字幕| 亚洲一区二区三区av无码| 国产精品无打码在线播放| 亚洲高清一区二区三区不卡| 亚洲综合久久一区二区| 色又黄又爽18禁免费网站现观看| 无码不卡中文字幕av| 欧美大波少妇在厨房被| 好吊妞国产欧美日韩免费观看| 久久精品国产精品青草| 国产成人国拍亚洲精品| 欧美xxxx做受视频| 久久99精品久久久久久| 伊人大香人妻在线播放| 人妻换着玩又刺激又爽| 国产乡下三级全黄三级| 国产高清成人免费视频在线观看| 久久熟妇人妻午夜寂寞影院| 九九久久精品国产免费看小说| 国产在线视频一区二区三区| 亚洲精品一品区二品区三品区| 麻豆自媒体 一区 二区| 日本 精品 高清不卡| 亚洲国产精品久久一线不卡| 伊人亚洲综合影院首页| 私人家庭影院5777| 国产露脸150部国语对白|