在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ABAT Antibody

  • 中文名稱:
    ABAT兔多克隆抗體
  • 貨號:
    CSB-PA001032ESR1HU
  • 規格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: 4-aminobutyrate aminotransferase, mitochondrial antibody at 10μg/ml
      Lane 1: Rat liver tissue
      Lane 2: Mouse pancreatic tissue
      Lane 3: Mouse kidney tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 56 kDa
      Observed band size: 56 kDa
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA001032ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA001032ESR1HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) ABAT Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    ABAT
  • 別名:
    (S) 3 amino 2 methylpropionate transaminase antibody; (S)-3-amino-2-methylpropionate transaminase antibody; 4 aminobutyrate aminotransferase antibody; 4 aminobutyrate aminotransferase; mitochondrial antibody; 4-aminobutyrate aminotransferase antibody; ABAT antibody; FLJ17813 antibody; FLJ30272 antibody; GABA aminotransferase antibody; GABA AT antibody; GABA T antibody; GABA transaminase antibody; GABA transferase antibody; GABA-AT antibody; GABA-T antibody; GABAT antibody; GABT_HUMAN antibody; Gamma amino N butyrate transaminase antibody; Gamma-amino-N-butyrate transaminase antibody; hCG1984265 antibody; L AIBAT antibody; L-AIBAT antibody; LAIBAT antibody; mitochondrial antibody; NPD009 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human, Mouse, Rat
  • 免疫原:
    Recombinant Human 4-aminobutyrate aminotransferase, mitochondrial protein (29-300AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine.
  • 基因功能參考文獻:
    1. This study utilized ER+ IBC to identify a metagene including ABAT and STC2 as predictive biomarkers for endocrine therapy resistance. PMID: 25771305
    2. A-to-G transition at nucleotide 754 of the human ABAT gene identified in lymphoblast cDNA (c.754A>G) results in substitution of an invariant arginine at amino acid 220 by lysine (p.Arg220Lys). This point mutation results in destabilization of the binding of pyridoxal-5'-phosphate to GABA-transaminase (required for transamination of GABA to succinic semialdehyde) and thus results in GABA-transaminase deficiency. PMID: 25485164
    3. Findings point to a possible role of ABAT gene-regulated GABA catabolism for an altered processing of somatosensory stimuli as a potential vulnerability marker for affective disorders. PMID: 22225676
    4. direct involvement of ABAT in pathways affecting lower esophageal sphincter (LES) control in gastro esophageal reflux disease PMID: 21552517
    5. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 20659789
    6. excessive prenatal GABA exposure in the central nervous system (CNS) is responsible for the clinical manifestations of GABA transaminase deficiency [case report] PMID: 20052547
    7. Marked differences in platelet uptake of GABA and activity of catabolic enzyme GABA-T between patients with generalized and localization-related epileptic syndromes. May indicate an impairment in function of brain GABAergic systems. PMID: 12694932
    8. results suggest that the Cys321 residue is essential for the catalytic function of GABAT, and that it is involved in the formation of a disulfide link between two monomers of human brain GABAT PMID: 15528998
    9. lysine 357 is essential for catalytic function of brain GABA transaminase, and is involved in binding PLP at the active site PMID: 15650327
    10. Analysis of the autistic disorder susceptibility locus suggests an association on chromosome 16p between GRIN2A and ABAT. PMID: 15830322

    顯示更多

    收起更多

  • 相關疾病:
    GABA transaminase deficiency (GABATD)
  • 亞細胞定位:
    Mitochondrion matrix.
  • 蛋白家族:
    Class-III pyridoxal-phosphate-dependent aminotransferase family
  • 組織特異性:
    Liver > pancreas > brain > kidney > heart > placenta.
  • 數據庫鏈接:

    HGNC: 23

    OMIM: 137150

    KEGG: hsa:18

    STRING: 9606.ENSP00000268251

    UniGene: Hs.336768



主站蜘蛛池模板: 玩弄少妇的肉体k8经典| 少妇无码一区二区三区| 亚洲国产成人va在线观看天堂| 男女啪啪免费观看的网址| 亚洲成年看片在线观看| 亚洲中文字幕无码中文字| 无码高潮少妇毛多水多水免费| 亚洲最新版av无码中文字幕| 成年站免费网站看v片在线| 国产精品一区二区熟女不卡| 日本中国内射bbxx| 老司机深夜18禁污污网站| 蜜桃麻豆www久久国产sex| 人妻无码中文久久久久专区| 少妇大叫太大太粗太爽了a片小说| 久久无码中文字幕无码| 久久精品国产2020| 国产精品欧美亚洲韩国日本久久| 日韩不卡手机视频在线观看| 国产精品国产午夜免费看福利| 亚洲乱色熟女一区二区三区丝袜| 奇米影视第4色| 欧美三级不卡在线播放| 亚洲超碰无码色中文字幕97| 99re6热在线精品视频播放| 国产精品久久久久av福利动漫| 国产精品亚洲五月天高清| 曰本女人牲交高潮视频| 国产精品对白刺激久久久| 黑人好猛厉害爽受不了好大撑| 欧美三級片黃色三級片黃色| 亚洲精品成人网站在线观看| 久久人搡人人玩人妻精品首页| 国产午夜精品一区二区三区老 | 精品国产乱码久久久久久婷婷| 成人免费看吃奶视频网站| 岛国av无码免费无禁网站麦芽| 在线观看特色大片免费视频| 4hu四虎永久在线观看| 日韩欧无码一区二区三区免费不卡 | 成人动漫综合网|