在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

AANAT Antibody

  • 中文名稱:
    AANAT兔多克隆抗體
  • 貨號:
    CSB-PA179815
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA179815(AANAT Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA179815(AANAT Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    AANAT
  • 別名:
    AA-NAT antibody; Aanat antibody; Aralkylamine N-acetyltransferase antibody; Arylalkylamine N acetyltransferase antibody; Serotonin acetylase antibody; Serotonin N-acetyltransferase antibody; SNAT antibody; SNAT_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Fusion protein of Human AANAT
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:1000-1:5000
    IHC 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N-acetylserotonin, the penultimate step in the synthesis of melatonin.
  • 基因功能參考文獻:
    1. Aggregate genetic variation in circadian rhythm and melatonin pathways were significantly associated with the risk of prostate cancer in data combining GAME-ON and PLCO, after Bonferroni correction (ppathway < 0.00625). The two most significant genes were NPAS2 (pgene = 0.0062) and AANAT (pgene = 0.00078); the latter being significant after Bonferroni correction. PMID: 28699174
    2. Data show that arylalkymine N-acetyltransferase (AANAT) levels and melatonin synthesis change after transient receptor potential channel 4 (TRPV4 channel) stimulation in ciliary body epithelial cells. PMID: 28368307
    3. these and related results indicate both a major involvement of the N-end rule pathway in the control of rodent AANATs and substantial differences in the regulation of rodent and human AANATs that stem from differences in their N-terminal sequences. PMID: 27339900
    4. There is dysregulation of the AANAT/ASMT/melatonin --> melatonin receptor axis in cholangiocarcinoma, which inhibited melatonin secretion and subsequently enhanced CCA growth. PMID: 21778461
    5. The expression of AANAT in epithelial cells of striated ducts in human submandibular glands. PMID: 21437622
    6. The functional expression of human SNA protein was closely associated with the elevated synthesis of N-acetylserotonin and melatonin in transgenic rice plants. PMID: 20586889
    7. Identified 17 sequence changes in AANAT gene of patients with major depression. Show evidence of the association of genetic variability in the AANAT gene with susceptibility to major depression. PMID: 20459461
    8. There is a significant increase in AANAT allele positivity at the single nucleotide polymorphism (alanine 129--> threonine) at between patients with DSPS & controls. AA-NAT could be a susceptibility gene for DSPS. PMID: 12736803
    9. Data suggest that the -263G/C single nucleotide polymorphism of arylalkylamine-N-acetyl-transferase (AA-NAT) may be an important determinant of the late/short sleep pattern. PMID: 15332344
    10. Single nucleotide polymorphisms in the AANAT gene identified thus far cannot explain the observed interindividual differences for nocturnal melatonin profiles in the subjects investigated. PMID: 18569588
    11. AANAT polymorphisms were not associated with adolescent idiopathic scoliosis. PMID: 18794762
    12. Observational study of genotype prevalence and gene-disease association. (HuGE Navigator) PMID: 17503170

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    Acetyltransferase family, AANAT subfamily
  • 組織特異性:
    Highly expressed in pineal gland and at lower levels in the retina. Weak expression in several brain regions and in the pituitary gland.
  • 數據庫鏈接:

    HGNC: 19

    OMIM: 600950

    KEGG: hsa:15

    STRING: 9606.ENSP00000250615

    UniGene: Hs.431417



主站蜘蛛池模板: 国产永久免费观看视频| 亚洲精品乱码久久久久久蜜桃不卡| 亚洲日韩激情无码一区| 国产成人+亚洲欧洲+综合| 777精品出轨人妻国产| 亚洲狠狠色成人综合网| 精品国产乱码久久久久久下载| 少妇爱做高清免费视频| 久久久久久久综合日本| 新版天堂资源中文8在线| 波多野美乳人妻hd电影欧美| 久久久久99精品成人片直播| 国产精品岛国久久久久| 粉嫩被粗大进进出出视频| 丁香五月亚洲中文字幕| 丰满少妇做爰视频爽爽和| 成人试看120秒体验区| 2021无码最新国产在线观看| 无码精品人妻一区二区三区人妻斩 | 又黄又爽又猛的视频免费| 亚洲aⅴ无码国精品中文字慕| 精品久久久久久国产潘金莲| 久久66热人妻偷产精品9| 久久精品水蜜桃av综合天堂| 国产三级av在线播放| 国产又色又爽无遮挡免费动态图| 成视频年人黄网站视频福利| 中本亚洲欧美国产日韩| 国内揄拍国内精品少妇| 欧美日韩一区二区三区视频播放 | 久久本色成人综合网| 天天天狠天天碰天天爱| 午夜亚洲福利在线老司机| 日韩国产成人精品视频| 日产无码中文字幕av| 国产精品一区二区手机在线观看| 太粗太深了太紧太爽了动态图男男| 成年男女免费视频网站| 欧美乱妇高清无乱码免费| 波多老师无码av中字专区| 久久精品超碰av无码|