在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Malate dehydrogenase, cytoplasmic (MDH1) (Active)

Unavailable
  • 中文名稱:
    人MDH1重組蛋白
  • 貨號:
    CSB-AP005651HU
  • 規格:
    ¥1740
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 95% as determined by SDS-PAGE.
  • 內毒素:
    Less than 1.0 EU/μg as determined by LAL method.
  • 生物活性:
    Its dehydrogenation activity from (S)-malate to oxaloacetate in the presense of NAD+ is determined to be greater than 1000 pmol/min/ug
  • 基因名:
    MDH1
  • Uniprot No.:
  • 別名:
    cytoplasmic; Cytosolic malate dehydrogenase; Diiodophenylpyruvate reductase; Malate dehydrogenase 1, NAD (soluble); Malate dehydrogenase; Malate dehydrogenase cytoplasmic; MDH s; mdh1; MDHA; MDHC_HUMAN; MDHs; MGC:1375; MOR2; Soluble malate dehydrogenase
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    E.coli
  • 分子量:
    37.5 kDa
  • 表達區域:
    2-334aa
  • 氨基酸序列
    SEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDCALPLLKDVIATDKEDVAFKDLDVAILVGSMPRREGMERKDLLKANVKIFKSQGAALDKYAKKSVKVIVVGNPANTNCLTASKSAPSIPKENFSCLTRLDHNRAKAQIALKLGVTANDVKNVIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGEFVTTVQQRGAAVIKARKLSSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVIKNKTWKFVEGLPINDFSREKMDLTAKELTEEKESAFEFLSSA
  • 蛋白標簽:
    C-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    0.2 μm Filtered 20 mM Tris-HCl, 150 mM NaCl, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Catalyzes the reduction of aromatic alpha-keto acids in the presence of NADH. Plays essential roles in the malate-aspartate shuttle and the tricarboxylic acid cycle, important in mitochondrial NADH supply for oxidative phosphorylation.
  • 基因功能參考文獻:
    1. expression of miR-126-5p suppresses the enzymatic activity of MDH1, mitochondrial respiration and caused cell death in non-small cell lung carcinoma cell lines. PMID: 29574159
    2. Data show that in the endogenous readthrough of the human MDH1 stop codon, the stop codon can encode tryptophan and arginine, and is tissue-specific. PMID: 27881739
    3. Proliferating cells rely on both MDH1 and LDH to replenish cytosolic NAD. PMID: 28263970
    4. Arginine methylation of MDH1 by CARM1 regulates cellular redox homeostasis and suppresses glutamine metabolism of pancreatic cancer. PMID: 27840030
    5. adipogenic differentiation may be regulated by the acetylation of MDH1 PMID: 22693256
    6. The MDH1 gene is not the cause of RP28-linked autosomal recessive retinitis pigmentosa. PMID: 20011630
    7. expression of MDH1 is maintained in the adult heart but is not present in levels as high as in the fetus PMID: 15565635
    8. Malate Dehydrogenase directly regulates the Tumor Suppressor Protein p53-dependent apoptosis upon glucose deprivation and involved in maintaining cellular metabolic state and further determining cell death. PMID: 19229245

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    LDH/MDH superfamily, MDH type 2 family
  • 數據庫鏈接:

    HGNC: 6970

    OMIM: 154200

    KEGG: hsa:4190

    STRING: 9606.ENSP00000438144

    UniGene: Hs.526521



主站蜘蛛池模板: 亚洲欧美日产综合在线| 国产69囗曝吞精在线视频| 一本天堂v无码亚洲道久久| 真实国产乱子伦对白在线播放| 国产乡下三级全黄三级| 久久伊人色av天堂九九| av无码免费岛国动作片片段欣赏网| 又色又爽又黄的美女裸体网站 | 国产无遮挡又爽又黄大胸免费| 久9视频这里只有精品试看| 久久av无码精品人妻出轨 | 色欲来吧来吧天天综合网| 国产成人精品av| 国产乱子轮xxx农村| 久久精品66免费99精品| 免费无码成人av在线播放不卡| 最近2019免费中文第一页| 97久久香蕉国产线看观看| 国产丝袜在线精品丝袜不卡| 麻花豆传媒剧国产免费mv观看| 国产成人一区二区三区| 亚洲综合在线另类色区奇米| 亚洲色成人四虎在线观看| 久久中文骚妇内射| 国产麻豆md传媒视频| 日韩精品无码中文字幕一区二区| 成人伊人亚洲人综合网| 少妇人妻真实偷人精品视频| 亚洲国产精品一区第二页| 4480yy私人精品国产| 少妇高潮大叫好爽| 亚洲精品久久久久久中文字幕| 最新网站亚洲人成无码| 日韩 亚洲 欧美 国产 精品| 18禁成人网站免费观看| 秋霞鲁丝片av无码| 国产成人精品一区二区秒播| 蜜桃久久精品成人无码av| 欧亚精品一区三区免费| 国产精品久久国产精麻豆99网站| 国产午夜亚洲精品国产成人小说|