在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 單克隆抗體
  4. IL1F10 Monoclonal Antibody

IL1F10 Monoclonal Antibody

  • 中文名稱：
    IL1F10鼠單克隆抗體
  • 貨號：
    CSB-MA8378691A0m
  • 規(guī)格：
    ￥1320
  • 圖片：
    • Immunohistochemical of paraffin-embedded Human Colon cancer tissue using CSB-MA8378691A0m at dilution of 1:200.
    • Immunohistochemical of paraffin-embedded Human live cancer tissue using CSB-MA8378691A0m at dilution of 1:200.
    • Immunohistochemical of paraffin-embedded Human spleen tissue using CSB-MA8378691A0m at dilution of 1:200.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    IL1F10單克隆抗體（CUSABIO貨號：CSB-MA8378691A0m）是針對白細胞介素1家族成員IL-1F10研發(fā)的高特異性科研試劑，適用于人類樣本的ELISA檢測及免疫組化實驗。IL-1F10作為新型細胞因子，在調(diào)節(jié)炎癥反應、免疫應答及組織修復等過程中發(fā)揮重要作用，其表達水平與多種病理生理過程相關(guān)，是免疫調(diào)控機制研究的關(guān)鍵靶點之一。本產(chǎn)品采用雜交瘤技術(shù)制備，經(jīng)嚴格驗證可特異性識別天然構(gòu)象的IL-1F10蛋白，適用于精準檢測體外培養(yǎng)細胞、組織切片等樣本中的目標蛋白定位與表達量分析。科研人員可通過該抗體在炎癥性疾病機制研究、藥物靶點篩選及信號通路探索等方向開展實驗，尤其在探索IL-1F10與其他細胞因子相互作用、基因表達調(diào)控網(wǎng)絡(luò)等領(lǐng)域具有重要應用價值。該產(chǎn)品提供即用型穩(wěn)定配方，實驗重復性好，適用于多種蛋白檢測平臺，為免疫學、分子生物學及轉(zhuǎn)化醫(yī)學研究提供可靠工具。
  • 產(chǎn)品名稱：
    mouse anti-Homo sapiens (Human) IL1F10 monoclonal antibody
  • Uniprot No.：
  • 基因名：
    IL1F10
  • 別名：
    family of interleukin 1-theta antibody; FIL1 theta antibody; FIL1T antibody; FKSG75 antibody; IL 38 antibody; IL-1 theta antibody; IL-1F10 (canonical form IL-1F10a) antibody; IL-1F10 antibody; IL-1HY2 antibody; IL1 theta antibody; IL1F10 antibody; IL1FA_HUMAN antibody; IL1HY2 antibody; Interleukin 1 family member 10 (theta) antibody; Interleukin 1 receptor antagonist FKSG75 antibody; Interleukin 1 receptor antagonist homolog 2 antibody; Interleukin 1 receptor antagonist like FIL1 theta antibody; Interleukin-1 family member 10 antibody; Interleukin-1 HY2 antibody; Interleukin-1 theta antibody; interleukin-38 antibody
  • 宿主：
    mouse
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human IL1F10 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    monoclonal
  • 抗體亞型：
    IgG1
  • 純化方式：
    >95%,protein G purifed
  • 克隆號：
    2A2B3
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:50-1:500
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2.
  • 基因功能參考文獻：
    1. The serum level of IL-38 in the children in the acute phase of Kawasaki disease was significantly lower than that in the healthy control group PMID: 30022755
    2. IL-38 may play an important role in acute and/or chronic inflammation in anticancer drug-induced lung injury and acute exacerbation of idiopathic pulmonary fibrosis. PMID: 28942884
    3. IL-38 may exert its anti-inflammatory effects by decreasing the production of proinflammatory cytokines by macrophages and synovial fibroblasts. PMID: 28288964
    4. this clinical study demonstrates the elevation of anti-inflammatory cytokine IL-38 and the decrement of CD4+CD25highFoxP3+ and CD4+CD25highCD127- Treg in childhood asthma. The negative correlation of IL-38 and Treg lymphocytes may imply a negative feedback of the two anti-inflammatory factors in asthma. PMID: 27438823
    5. this study shows that in vivo expression of human IL-38 in mice has hepatoprotective effects against Con A-induced liver injury by inhibition of inflammatory cytokine production PMID: 27723569
    6. Higher serum IL-38 levels before treatment indicate a greater probability of viral response to telbivudine treatment in chronic hepatitis B. PMID: 27182162
    7. results indicate that circulating IL-38 is a potentially novel biomarker for patients with ST-segment elevation myocardial infarction PMID: 26819499
    8. Data suggest that IL-38 may be protective in SLE. A strong association between IL-38 and SLE severity suggests that IL-38 expression is driven by processes linked to SLE pathogenesis. PMID: 26314375
    9. rs6759676, closest gene locus IL1F10 is associated with increased circulating levels of IL-1 receptor antagonist, a protective factor in development of insulin resistance. PMID: 24969107
    10. The IL1A locus was strongly associated with alkylosing spondyloarthritis phenotype, whereas IL1F10 was associated with non-alkylosing spondyloarthritis. PMID: 22312160
    11. These data provide evidence that IL-38 binds to the IL-36R, as does IL-36Ra.[IL-38, IL-36R] PMID: 22315422

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Secreted.
  • 蛋白家族：
    IL-1 family
  • 組織特異性：
    Expressed in fetal skin, spleen and tonsil. Expressed mostly in the basal epithelia of skin and in proliferating B-cells of the tonsil.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 15552

    OMIM: 615296

    KEGG: hsa:84639

    STRING: 9606.ENSP00000341794

    UniGene: Hs.306974



主站蜘蛛池模板： 亚洲精品国产一区二区三| 女人摸下面自熨视频在线播放| 欧美人与禽z0zo牲伦交| 欧美黑人xxxx性高清版| 久久www免费人成_看片老司机| 无码国模国产在线观看| 国产亚洲成av人片在线观黄桃| 天天弄天天模| 无码少妇一区二区三区芒果| 亚洲日韩乱码中文字幕| 欧美 在线 成 人怡红院| 国产拍揄自揄精品视频| 豆国产95在线 | 亚洲| 国产男女爽爽爽免费视频| 色屁屁www影院免费观看入口| 极品美女在线观看免费直播| 欧美日韩国产专区一区二区| 国产在线一区二区三区四区五区| 成年美女黄网站色大片免费看| 亚洲日韩av一区二区三区四区| 国产亚洲精品久久久久久小说| 日日碰狠狠躁久久躁96| 在线观看国产精品va| 国产精品熟妇一区二区三区四区| 色噜噜狠狠色综合久夜色撩人| 中文字幕人妻被公上司喝醉在线 | 国产又色又爽又黄的在线观看视频| 少妇爆乳无码专区网站| 精品乱码一区二区三四五区| 人妻无码第一区二区三区| 无码人妻丰满熟妇区五十路 | 国产国拍精品av在线观看按摩| 污污内射在线观看一区二区少妇 | 情欲少妇人妻100篇| 狠狠做久久深爱婷婷| 又大又硬又黄的免费视频| 亚洲人成网站18禁止无码| 日韩无码专区| 韩国乱码片免费看| 少妇高潮喷水正在播放| 精品无码午夜福利理论片|