在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 試劑盒
  3. 酶聯免疫試劑盒
  4. Human Interleukin-1 family member 10(IL1F10) ELISA kit

Human Interleukin-1 family member 10(IL1F10) ELISA kit

  • 中文名稱：
    人白介素1家族成員10(IL1F10)酶聯免疫試劑盒
  • 貨號：
    CSB-EL011615HU
  • 規格：
    96T/48T
  • 價格：
    ￥3600/￥2500
  • 其他：

產品詳情

  • 產品描述：
    人白介素1家族成員10(IL1F10)酶聯免疫試劑盒（CSB-EL011615HU）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的IL1F10含量。IL1F10，又稱IL-38，是白細胞介素1家族的一員，參與調節適應性及先天免疫反應。其研究背景涉及免疫調節，通過影響細胞因子產生發揮作用，單獨不誘導細胞因子產生，但在免疫反應中發揮調節作用。試劑盒檢測范圍為31.25 pg/mL-2000 pg/mL，適用于基礎科研中探索IL1F10在炎癥相關疾病模型中的作用機制、評估實驗動物或細胞模型的蛋白表達動態變化，以及篩選調控該因子的藥物或化合物。科研人員可通過本產品分析不同處理條件下生物樣本（如炎癥模型血清、腫瘤組織勻漿或免疫細胞培養上清）中IL1F10的表達水平，為免疫調節研究及疾病機理探索提供可靠數據支持。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
  • 別名：
    family of interleukin 1-theta ELISA Kit; FIL1 theta ELISA Kit; FIL1T ELISA Kit; FKSG75 ELISA Kit; IL 38 ELISA Kit; IL-1 theta ELISA Kit; IL-1F10 (canonical form IL-1F10a) ELISA Kit; IL-1F10 ELISA Kit; IL-1HY2 ELISA Kit; IL1 theta ELISA Kit; IL1F10 ELISA Kit; IL1FA_HUMAN ELISA Kit; IL1HY2 ELISA Kit; Interleukin 1 family member 10 (theta) ELISA Kit; Interleukin 1 receptor antagonist FKSG75 ELISA Kit; Interleukin 1 receptor antagonist homolog 2 ELISA Kit; Interleukin 1 receptor antagonist like FIL1 theta ELISA Kit; Interleukin-1 family member 10 ELISA Kit; Interleukin-1 HY2 ELISA Kit; Interleukin-1 theta ELISA Kit; interleukin-38 ELISA Kit
  • 縮寫：
    IL1F10
  • Uniprot No.：
  • 種屬：
    Homo sapiens (Human)
  • 樣本類型：
    serum, plasma, tissue homogenates
  • 檢測范圍：
    31.25 pg/mL-2000 pg/mL
  • 靈敏度：
    7.81 pg/mL
  • 反應時間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領域：
    Immunology
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 線性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of human IL1F10 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    SampleSerum(n=4)
    1:1Average %97
    Range %92-104
    1:2Average %84
    Range %80-88
    1:4Average %105
    Range %100-113
    1:8Average %95
    Range %90-100
  • 回收率：
    The recovery of human IL1F10 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample TypeAverage % RecoveryRange
    Serum (n=5) 8880-92
    EDTA plasma (n=4)9490-99
  • 標準曲線：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    pg/ml OD1OD2AverageCorrected
    20002.070 2.217 2.144 2.044
    10001.393 1.321 1.357 1.257
    5000.756 0.809 0.783 0.683
    2500.421 0.445 0.433 0.333
    1250.267 0.254 0.261 0.161
    62.50.196 0.183 0.190 0.090
    31.250.151 0.154 0.153 0.053
    00.103 0.096 0.100
  • 數據處理：
  • 貨期：
    3-5 working days

引用文獻

產品評價

靶點詳情

  • 功能：
    Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2.
  • 基因功能參考文獻：
    1. The serum level of IL-38 in the children in the acute phase of Kawasaki disease was significantly lower than that in the healthy control group PMID: 30022755
    2. IL-38 may play an important role in acute and/or chronic inflammation in anticancer drug-induced lung injury and acute exacerbation of idiopathic pulmonary fibrosis. PMID: 28942884
    3. IL-38 may exert its anti-inflammatory effects by decreasing the production of proinflammatory cytokines by macrophages and synovial fibroblasts. PMID: 28288964
    4. this clinical study demonstrates the elevation of anti-inflammatory cytokine IL-38 and the decrement of CD4+CD25highFoxP3+ and CD4+CD25highCD127- Treg in childhood asthma. The negative correlation of IL-38 and Treg lymphocytes may imply a negative feedback of the two anti-inflammatory factors in asthma. PMID: 27438823
    5. this study shows that in vivo expression of human IL-38 in mice has hepatoprotective effects against Con A-induced liver injury by inhibition of inflammatory cytokine production PMID: 27723569
    6. Higher serum IL-38 levels before treatment indicate a greater probability of viral response to telbivudine treatment in chronic hepatitis B. PMID: 27182162
    7. results indicate that circulating IL-38 is a potentially novel biomarker for patients with ST-segment elevation myocardial infarction PMID: 26819499
    8. Data suggest that IL-38 may be protective in SLE. A strong association between IL-38 and SLE severity suggests that IL-38 expression is driven by processes linked to SLE pathogenesis. PMID: 26314375
    9. rs6759676, closest gene locus IL1F10 is associated with increased circulating levels of IL-1 receptor antagonist, a protective factor in development of insulin resistance. PMID: 24969107
    10. The IL1A locus was strongly associated with alkylosing spondyloarthritis phenotype, whereas IL1F10 was associated with non-alkylosing spondyloarthritis. PMID: 22312160
    11. These data provide evidence that IL-38 binds to the IL-36R, as does IL-36Ra.[IL-38, IL-36R] PMID: 22315422

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Secreted.
  • 蛋白家族：
    IL-1 family
  • 組織特異性：
    Expressed in fetal skin, spleen and tonsil. Expressed mostly in the basal epithelia of skin and in proliferating B-cells of the tonsil.
  • 數據庫鏈接：

    HGNC: 15552

    OMIM: 615296

    KEGG: hsa:84639

    STRING: 9606.ENSP00000341794

    UniGene: Hs.306974



主站蜘蛛池模板： 亚洲精品午夜久久久伊人| 国产亚洲欧洲aⅴ综合一区| 真人做人60分钟啪啪免费看| 人妻丰满熟妞av无码区| 国产成人a人亚洲精v品无码| 日本高清在线www3344| 自拍偷在线精品自拍偷99| 久久久久亚洲精品无码网址| 五十路丰满中年熟女中出| 国产成 人 综合 亚洲网站| 亚洲不乱码卡一卡二卡4卡5| 丁香花在线影院观看在线播放| 农村乱人伦一区二区| 中文字幕无码精品亚洲资源网 | 日本丰满少妇xxxx| 欧洲免费一区二区三区视频| 麻豆果冻精东九一传媒mv| 风流少妇按摩来高潮| 日韩 欧美 动漫 国产 制服| 亚洲中文字幕无码久久2018| 亚洲精品tv久久久久久久久j| 正在播放国产真实哭都没用| 免费特级毛片| 国产白嫩美女在线观看| 人与嘼av免费| 综合激情五月综合激情五月激情1| 69成人免费视频无码专区| 国产av激情无码久久| 国产精品成熟老女人| www成人国产高清内射| 又爆又大又粗又硬又黄的a片 | 无码人妻av免费一区二区三区| 亚洲欧美日韩另类丝袜一区| 国产成人无码精品一区二区三区| 国产精成人品| 国产精品无码成人午夜电影| 青春草在线视频观看| 国产午夜高潮熟女精品av软件 | 免费观看国产小粉嫩喷水| 久久一本久综合久久爱| 精品久久久无码中文字幕边打电话 |