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中文名稱:小鼠糖化血紅蛋白A1c(GHbA1c)酶聯免疫試劑盒
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貨號:CSB-E08141m
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規格:96T/48T
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價格:¥3800/¥2500
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其他:
產品詳情
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產品描述:小鼠糖化血紅蛋白A1c(GHbA1c)酶聯免疫試劑盒(CSB-E08141m)為競爭法ELISA試劑盒,定量檢測lysatesforRBC樣本中的GHbA1c含量。GHbA1c即糖化血紅蛋白,反映過去 2 至 3 個月的平均血糖水平。它是評估糖尿病長期血糖控制的重要指標。研究機制上,其由血紅蛋白與葡萄糖非酶促結合而成,結合量與血糖濃度正相關,可更全面反映血糖波動情況。試劑盒檢測范圍為62.5 ng/ml-4000 ng/ml.,適用于科研實驗中紅細胞裂解液樣本的定量分析;常用于糖尿病相關機制研究及代謝性疾病模型的評估;適用于體外實驗中對紅細胞樣本的糖化程度分析,可應用于糖尿病動物模型研究、降糖藥物作用機制探索或慢性高血糖對紅細胞功能影響的科研項目中本品僅用于科研,不用于臨床診斷,產品具體參數及操作步驟詳見產品說明書。
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縮寫:GHbA1c
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種屬:Mus musculus (Mouse)
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樣本類型:lysates for RBC
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檢測范圍:62.5 ng/ml-4000 ng/ml.
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靈敏度:15.6ng/ml
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反應時間:1-5h
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樣本體積:50-100ul
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檢測波長:450 nm
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研究領域:Others
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測定原理:quantitative
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測定方法:Competitive
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精密度:
Intra-assay Precision (Precision within an assay): CV%<8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV%<10%
Three samples of known concentration were tested in twenty assays to assess.
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線性度:
To assess the linearity of the assay, samples were spiked with high concentrations of mouse GHbA1c in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
Sample
Lysate for RBC(n=4)
1:200
Average %
84
Range %
80-96
1:400
Average %
90
Range %
83-99
1:800
Average %
87
Range %
82-100
1:1600
Average %
85
Range %
82-98
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回收率:
The recovery of mouse GHbA1c spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
Sample Type
Average % Recovery
Range
Lysate for RBC (n=5)
85
82-95
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標準曲線:
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
ng/ml
OD1
OD2
Average
4000
0.176
0.184
0.180
2000
0.259
0.267
0.263
1000
0.363
0.378
0.370
500
0.520
0.529
0.525
250
0.794
0.821
0.807
125
1.174
1.233
1.204
62.5
1.724
1.684
1.704
0
2.608
2.625
2.616
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數據處理:
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貨期:3-5 working days
引用文獻
- Profile of the bile acid FXR-FGF15 pathway in the glucolipid metabolism disorder of diabetic mice suffering from chronic stress W Cai,PeerJ,2023
- Serum and urine metabolomics study revealed the amelioration of Gynura bicolor extract on high fat diet-fed and streptozotocin-induced type 2 diabetic mice based on UHPLC-MS/MS X Ding,Journal of pharmaceutical and biomedical analysis,2023
- Vancomycin relieves tacrolimus-induced hyperglycemia by eliminating gut bacterial beta-glucuronidase enzyme activity J Gao,Gut microbes,2024
- TRPC3 Regulates Islet Beta‐Cell Insulin Secretion G Rached,Advanced Science,2023
- Long-term statins administration exacerbates diabetic nephropathy via ectopic fat deposition in diabetic mice T Huang,Nature communications,2023
- VLA4-Enhanced Allogeneic Endothelial Progenitor Cell-Based Therapy Preserves the Aortic Valve Function in a Mouse Model of Dyslipidemia and Diabetes A Filippi,Pharmaceutics,2022
- The Combinatorial Effect of Acetate and Propionate on High-Fat Diet Induced Diabetic Inflammation or Metaflammation and T Cell Polarization DK Mandaliya,Inflammation,2020
- Complement Properdin Regulates the Metabolo-Inflammatory Response to a High Fat Diet RC Thomas,Medicina,2020
- Glyoxalase 1 Prevents Chronic Hyperglycemia Induced Heart-Explant Derived Cell Dysfunction Villanueva M, et al,Theranostics,2019
- Diabetes-induced early molecular and functional changes in aortic heart valves in a murine model of atherosclerosis Tucureanu M M, et al,Diabetes and Vascular Disease Research,2019
- Therapy of empagliflozin plus metformin on T2DM mice shows no higher amelioration for glucose and lipid metabolism than empagliflozin monotherapy Wang Z, et al,Life Sciences,2019
- Loss of complex O-glycosylation impairs exocrine pancreatic function and induces MODY8-like diabetes in mice Wolters-Eisfeld G.et al,experimental and molecular medicine,2018
- Glyoxalase 1 Attenuates the Effects of Chronic Hyperglycemia on Explant-Derived Cardiac Stem Cells Villanueva.et al,/,2017
- Vitamin D3 supplementation of a high fat high sugar diet ameliorates prediabetic phenotype in female LDLR Ramiar Kheder.et al,J BONE MINER RES,2017
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