Human T-complex protein 1 subunit epsilon(CCT5) ELISA kit
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中文名稱:人T復合物蛋白1亞基ε(CCT5)酶聯免疫試劑盒
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貨號:CSB-EL004862HU
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規格:96T/48T
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價格:¥3600/¥2500
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其他:
產品詳情
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產品描述:人T復合物蛋白1亞基ε(CCT5)酶聯免疫試劑盒(CSB-EL004862HU)為雙抗夾心法ELISA試劑盒,定量檢測血清、血漿,組織勻漿、細胞裂解物樣本中的CCT5含量。CCT5是一種重要靶點。它屬于分子伴侶蛋白家族,在細胞內參與眾多蛋白質的折疊過程。目前研究關注其在細胞內穩態維持和疾病發生發展中的作用機制,了解其與疾病的關聯,有望為相關疾病的治療提供新的靶點和策略。試劑盒檢測范圍為15.6 pg/mL-1000 pg/mL,適用于體外培養細胞模型、動物組織或液體樣本中CCT5表達水平的動態監測,為探索其在細胞增殖、凋亡調控或疾病模型中的功能提供定量分析工具,廣泛用于分子生物學、病理機制及藥物干預效果評估等基礎研究領域。本品僅用于科研,不用于臨床診斷,產品具體參數及操作步驟詳見產品說明書。
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別名:CCT 5 ELISA Kit; CCT epsilon ELISA Kit; CCT-epsilon ELISA Kit; CCT5 ELISA Kit; CCTE ELISA Kit; CCTepsilon ELISA Kit; Chaperonin containing T-complex polypeptide 1; subunit 5 ELISA Kit; Chaperonin containing TCP 1 epsilon ELISA Kit; Chaperonin containing TCP 1 subunit 5 ELISA Kit; Chaperonin containing TCP 1 subunit 5 epsilon ELISA Kit; Chaperonin containing TCP1 epsilon ELISA Kit; Chaperonin containing TCP1 subunit 5 ELISA Kit; Chaperonin containing TCP1 subunit 5 epsilon ELISA Kit; KIAA0098 ELISA Kit; T complex protein 1 epsilon subunit ELISA Kit; T complex protein 1 subunit epsilon ELISA Kit; T-complex protein 1 subunit epsilon ELISA Kit; TCP 1 epsilon ELISA Kit; TCP-1-epsilon ELISA Kit; TCP1epsilon ELISA Kit; TCPE ELISA Kit; TCPE_HUMAN ELISA Kit
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縮寫:CCT5
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Uniprot No.:
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種屬:Homo sapiens (Human)
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樣本類型:serum, plasma,tissue homogenates, cell lysates
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檢測范圍:15.6 pg/mL-1000 pg/mL
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靈敏度:3.9 pg/mL
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反應時間:1-5h
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樣本體積:50-100ul
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檢測波長:450 nm
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研究領域:Signal Transduction
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測定原理:quantitative
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測定方法:Sandwich
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數據處理:
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貨期:3-5 working days
相關產品
靶點詳情
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功能:Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin.
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基因功能參考文獻:
- CCT5 complex caps mutant mHTT fibrils at their tips and encapsulates mHTT oligomers, providing a structural description of the inhibition of mHTTQ46-Ex1 by CCT5 complex and a shared mechanism of mHTT inhibition between TRiC chaperonin and the CCT5 complex PMID: 25995452
- H147R CCT5 was not as efficient in chaperoning these substrates as wild type CCT5. PMID: 25124038
- introduction of the truncated human CCT epsilon subunit into yeast cells PMID: 22232265
- A missense mutation within the CCT5 gene is associated with autosomal recessive mutilating sensory neuropathy with spastic paraplegia. PMID: 16399879
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相關疾病:Neuropathy, hereditary sensory, with spastic paraplegia, autosomal recessive (HSNSP)
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亞細胞定位:Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
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蛋白家族:TCP-1 chaperonin family
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數據庫鏈接:
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