在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 試劑盒
  3. 酶聯免疫試劑盒
  4. Human Complement factor H-related protein 2(CFHR2) ELISA kit

Human Complement factor H-related protein 2(CFHR2) ELISA kit

  • 中文名稱：
    人補體因子H相關蛋白2(CFHR2)酶聯免疫試劑盒
  • 貨號：
    CSB-EL005275HU
  • 規格：
    96T/48T
  • 價格：
    ￥3600/￥2500
  • 其他：

產品詳情

  • 產品描述：
    人補體因子H相關蛋白2(CFHR2)酶聯免疫試劑盒（CSB-EL005275HU）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的CFHR2含量。CFHR2屬于補體因子H相關基因家族，位于染色體1上，參與補體調節。其突變與致密性沉積病和非典型溶血性尿毒癥綜合征有關。研究顯示，CFHR2可能通過調節補體系統活性，影響脂質代謝，在免疫調節中發揮重要作用。試劑盒檢測范圍為6.25 ng/mL-400 ng/mL，適用于體外細胞實驗、疾病機制研究及生物標志物探索等科研場景，可為補體相關疾病的分子機制解析、藥物靶點驗證及治療策略開發提供精準的定量分析工具，尤其適合免疫學、病理學及轉化醫學領域的實驗室使用本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
  • 別名：
    CFHL2 ELISA Kit; CFHR2 ELISA Kit; Complement factor H related protein 2 ELISA Kit; Complement factor H-related 2 ELISA Kit; Complement factor H-related protein 2 ELISA Kit; DDESK59 ELISA Kit; Factor H-related gene 2 ELISA Kit; FHR 2 ELISA Kit; FHR-2 ELISA Kit; FHR2 ELISA Kit; FHR2_HUMAN ELISA Kit; H factor (complement)-like 3 ELISA Kit; H factor like 3 ELISA Kit; H factor like protein 2 ELISA Kit; H factor-like 3 ELISA Kit; H factor-like protein 2 ELISA Kit; HFL3 ELISA Kit
  • 縮寫：
  • Uniprot No.：
  • 種屬：
    Homo sapiens (Human)
  • 樣本類型：
    serum, plasma, tissue homogenates
  • 檢測范圍：
    6.25 ng/mL-400 ng/mL
  • 靈敏度：
    1.56 ng/mL
  • 反應時間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領域：
    Immunology
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 線性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of human CFHR2 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    　 Sample Serum(n=4)
    1:100 Average % 91
    Range % 87-95
    1:200 Average % 96
    Range % 90-102
    1:400 Average % 104
    Range % 98-109
    1:800 Average % 92
    Range % 86-98
  • 回收率：
    The recovery of human CFHR2 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample Type Average % Recovery Range
    Serum (n=5) 101 97-105
    EDTA plasma (n=4) 94 87-98
  • 標準曲線：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    ng/ml OD1 OD2 Average Corrected
    400 2.520 2.637 2.579 2.485
    200 2.124 2.205 2.165 2.071
    100 1.446 1.557 1.502 1.408
    50 0.937 0.923 0.930 0.836
    25 0.458 0.461 0.460 0.366
    12.5 0.271 0.283 0.277 0.183
    6.25 0.156 0.163 0.160 0.066
    0 0.093 0.095 0.094 　
  • 數據處理：
  • 貨期：
    3-5 working days

產品評價

靶點詳情

  • 功能：
    Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. Can associate with lipoproteins and may play a role in lipid metabolism.
  • 基因功能參考文獻：
    1. Studies indicate an association between CFHR2-rs2986127 and acute anterior uveitis (AAU) diagnosis. PMID: 27306586
    2. Next-generation sequencing of the CFH region identified putatively functional variants (missense, splice site and indel) on the four common haplotypes. We found no expression of any of the five CFH-related genes in the retina or RPE/Choroid/Sclera, in contrast to the liver, which is the main source of the circulating proteins. [CFHR2] PMID: 27196323
    3. Thus CFHR2 likely acts in concert with factor H, as CFHR2 inhibits convertases while simultaneously allowing factor H assisted degradation by factor I. PMID: 24260121
    4. A hybrid CFHR2-CFHR5 plasma protein, arising from a chromosomal deletion mutation stabilizes the C3 convertase and reduces factor H-mediated convertase decay. PMID: 24334459
  • 亞細胞定位：
    Secreted.
  • 組織特異性：
    Expressed by the liver and secreted in plasma.
  • 數據庫鏈接：

    HGNC: 4890

    OMIM: 600889

    KEGG: hsa:3080

    STRING: 9606.ENSP00000356385

    UniGene: Hs.632450



主站蜘蛛池模板： 亚洲va久久久噜噜噜久久4399| 国产亚洲精久久久久久无码苍井空 | 337p亚洲日本中国大胆69| 羞羞影院午夜男女爽爽| 中文字幕亚洲综合久久菠萝蜜| 人妻激情另类乱人伦人妻| 欲求不满邻居的爆乳在线播放| 亚洲一线产区二线产区分布| 国产国产精品人在线视| 天天躁日日躁狠狠躁欧美老妇小说 | 中文字幕人妻中文av不卡专区| 男人用嘴添女人私密视频| 国产精品色拉拉| 成年女人看片永久免费视频 | 无码免费一区二区三区免费播放| 国产如狼似虎富婆找强壮黑人| 妲己丰满人熟妇大尺度人体艺| 午夜精品久久久久久| 激情毛片无码专区| 国内精品久久久久影院网站| 中文字幕在线精品视频| 人妻激情偷乱视频一区二区三区| 天天躁日日躁狠狠躁2018 | 秋霞鲁丝无码一区二区三区| 精品无码成人片一区二区| 亚洲成a人片在线观看国产| 小sao货水好多真紧h无码视频| 成人电线在线播放无码| 亚洲hdmi高清线| 亚洲精品乱码久久久久久蜜桃图片 | 人人妻一区二区三区| 亚洲美女视频高清在线看| 亚洲一卡二卡三卡四卡无卡麻豆| 国产高清成人免费视频在线观看| 交换交换乱杂烩系列yy| 国产精品天堂avav在线| 国产成人无码a区精油按摩| 欧美 亚洲 国产 另类| 裸体女人高潮毛片| 国产精品va在线观看无码不卡| 西西人体444www大胆无码视频|