在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 試劑盒
  3. 酶聯(lián)免疫試劑盒
  4. Human Cartilage intermediate layer protein 1(CILP) ELISA kit

Human Cartilage intermediate layer protein 1(CILP) ELISA kit

  • 中文名稱：
    人軟骨中間層蛋白1(CILP)酶聯(lián)免疫試劑盒
  • 貨號：
    CSB-EL005437HU
  • 規(guī)格：
    96T/48T
  • 價(jià)格：
    ￥3600/￥2500
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    人軟骨中間層蛋白1(CILP)酶聯(lián)免疫試劑盒（CSB-EL005437HU）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的CILP含量。CILP（Contrastive Language-Image Pre-Training）是一種由OpenAI提出的預(yù)訓(xùn)練模型，旨在通過對比學(xué)習(xí)預(yù)訓(xùn)練語言和圖像的表示，以實(shí)現(xiàn)圖像和文本之間的相互理解。該模型通過大量圖像與文本對進(jìn)行預(yù)訓(xùn)練，采用自監(jiān)督學(xué)習(xí)方法，通過度量圖像與文本之間的相似性來提高模型的表現(xiàn)能力。試劑盒檢測范圍為93.75 pg/mL-6000 pg/mL，該產(chǎn)品適用于體外研究軟骨組織工程模型中的基質(zhì)代謝調(diào)控、退行性關(guān)節(jié)疾病動(dòng)物模型的生物標(biāo)志物追蹤，以及臨床前研究中的軟骨修復(fù)效果評估等科研場景，為探索軟骨病變機(jī)制及潛在干預(yù)策略提供可靠工具。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
  • 別名：
    Cartilage intermediate layer protein 1 ELISA Kit; Cartilage intermediate layer protein 1 C1 ELISA Kit; Cartilage intermediate layer protein 1 C2 ELISA Kit; cartilage intermediate layer protein ELISA Kit; cartilage intermediate layer protein; nucleotide pyrophosphohydrolase ELISA Kit; Cartilage intermediate-layer protein ELISA Kit; CILP 1 ELISA Kit; CILP ELISA Kit; CILP-1 ELISA Kit; CILP1_HUMAN ELISA Kit; HGNC:1980 ELISA Kit; HsT18872 ELISA Kit
  • 縮寫：
    CILP
  • Uniprot No.：
  • 種屬：
    Homo sapiens (Human)
  • 樣本類型：
    serum, plasma, tissue homogenates
  • 檢測范圍：
    93.75 pg/mL-6000 pg/mL
  • 靈敏度：
    23.4 pg/mL
  • 反應(yīng)時(shí)間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領(lǐng)域：
    Signal Transduction
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 線性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of human CILP in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    SampleSerum(n=4)
    1:5Average %94
    Range %90-98
    1:10Average %105
    Range %100-112
    1:20Average %84
    Range %80-88
    1:40Average %95
    Range %90-100
  • 回收率：
    The recovery of human CILP spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample TypeAverage % RecoveryRange
    Serum (n=5) 9389-98
    EDTA plasma (n=4)9894-106
  • 標(biāo)準(zhǔn)曲線：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    pg/ml OD1OD2AverageCorrected
    60002.098 2.201 2.150 2.027
    30001.512 1.454 1.483 1.360
    15000.983 0.934 0.959 0.836
    7500.611 0.643 0.627 0.504
    3750.330 0.338 0.334 0.211
    187.50.282 0.302 0.292 0.169
    93.750.192 0.207 0.200 0.077
    00.125 0.120 0.123
  • 數(shù)據(jù)處理：
  • 貨期：
    3-5 working days

產(chǎn)品評價(jià)

相關(guān)問答

■ 常見問題解答
Q:

what part of the protein this ELISA kit targets? As I am aware,
the Cilp gene encodes a precursor that is cleaved into two fragments.
I was curious as to whether this kit targets a specific fragment.

A:
Thanks for your inquiry!
CSB-EL005437HU
This kit is designed according to: https://www.uniprot.org/uniprot/O75339.
It detects CILP protein. The two fragments you mentioned should be C1 and C2. Sorry we are not clear if these 2 forms can be detected out or not. If the fragment is within the antibody's recognition area, then it can be detected out. However, in general the protein has spatial structure, so it is difficult to predict if it can be detected out or not. We suggest you do a pretest first.
Pls let me know if you have any further questions. Thank you.

靶點(diǎn)詳情

  • 功能：
    Probably plays a role in cartilage scaffolding. May act by antagonizing TGF-beta1 (TGFB1) and IGF1 functions. Has the ability to suppress IGF1-induced proliferation and sulfated proteoglycan synthesis, and inhibits ligand-induced IGF1R autophosphorylation. May inhibit TGFB1-mediated induction of cartilage matrix genes via its interaction with TGFB1. Overexpression may lead to impair chondrocyte growth and matrix repair and indirectly promote inorganic pyrophosphate (PPi) supersaturation in aging and osteoarthritis cartilage.
  • 基因功能參考文獻(xiàn)：
    1. CILP rs2073711 TT is associated with increased risk of symmetrical hand osteoarthritis particularly in individuals with low variation in work tasks. PMID: 29233086
    2. Meta-analysis. Our results confirm the positive association between CILP and intervertebral disc degeneration, providing novel clues for clarifying the role of CILP in the development of IVD. PMID: 27359356
    3. CILP is involved in the etiology of intervertebral disc degeneration among young adults. PMID: 22107760
    4. The researchers found that the single nucleotide polymorphism (1184T/C) of the CILP gene is associated an increased risk of lumbar disc degeneration in male athletes. PMID: 20724643
    5. CILP regulates TGF-beta signaling and that this regulation has a crucial role in the etiology and pathogenesis of LDD. PMID: 15864306
    6. These observations, together with the finding that CILP protein binds and inhibits TGF-beta1, suggest that CILP and TGF-beta1 may form a functional feedback loop that controls chondrocyte metabolism. PMID: 16413503
    7. SNP analysis suggested that the CILP gene is not a major risk factor for symptoms of lumbar disc disease in Finnish or Chinese populations. PMID: 17220213
    8. the CILP gene 1184T/C polymorphism is a significant risk factor for lumbar disc degeneration occurrence in Japanese collegiate judo athletes PMID: 19569011

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Intervertebral disc disease (IDD)
  • 亞細(xì)胞定位：
    Secreted, extracellular space, extracellular matrix.
  • 組織特異性：
    Specifically expressed in cartilage. Localizes in the intermediates layer of articular cartilage but neither in the superficial nor in the deepest regions. Specifically and highly expressed in intervertebral disk tissue. Expression increases with aging in
  • 數(shù)據(jù)庫鏈接：

    HGNC: 1980

    OMIM: 603489

    KEGG: hsa:8483

    STRING: 9606.ENSP00000261883

    UniGene: Hs.442180



主站蜘蛛池模板： 久艹视频免费看| 国产日韩欧美| 亚洲国精产品一二二线| 久久精品国产精品国产一区| 国产亚洲日韩妖曝欧美| 48沈阳熟女高潮嗷嗷叫| 女人爽到高潮免费看视频| 亚欧免费无码aⅴ在线观看蜜桃 | 国产电影一区二区三区| 国产男女爽爽爽免费视频| 天天综合亚洲色在线精品| 日韩av无码中文无码电影| 欧美最猛黑人xxxxx猛交| 国产网友自拍在线视频| 2021精品国夜夜天天拍拍| 日本韩国亚洲欧美在线| 少妇人妻偷人精品视频| 97se亚洲国产综合自在线观看| 婷婷五月日韩av永久免费| 亚洲国产欧美中文丝袜日韩| 国产亚av手机在线观看| 久久aⅴ无码av高潮av喷吹 | 国产成人精品.视频| 国产无遮挡免费真人视频在线观看| 新版天堂资源中文8在线| 免费午夜爽爽爽www视频十八禁| 女人爽到喷水的视频大全| 久久综合av色老头免费观看| 亚洲熟妇少妇任你躁在线观看无码| 亚洲国产美女精品久久久久∴| 日本少妇xxx做受| 久久大香国产成人av| 国产高清成人免费视频在线观看 | 精品麻豆国产色欲色欲色欲www| 宅男色影视亚洲人在线 | 国产97在线 | 亚洲| 饥渴少妇av无码影片| 亚洲欧洲日产国码无码| 国产免费看插插插视频| 樱花草在线社区www中国中文| 国产欧美丝袜在线二区|