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Your Good Partner in Biology Research

YES1

Tyrosine-protein kinase Yes is a protein in humans that is encoded by YES1 gene. Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation. Stimulation by receptor tyrosine kinases (RTKs) including EGRF, PDGFR, CSF1R and FGFR leads to recruitment of YES1 to the phosphorylated receptor, and activation and phosphorylation of downstream substrates. Upon EGFR activation, promotes the phosphorylation of PARD3 to favor epithelial tight junction assembly. Participates in the phosphorylation of specific junctional components such as CTNND1 by stimulating the FYN and FER tyrosine kinases at cell-cell contacts.

YES1 Antibodies

YES1 for Homo sapiens (Human)

YES1 Proteins

YES1 Proteins for Homo sapiens (Human)

YES1 Proteins for Gallus gallus (Chicken)

YES1 Proteins for Xenopus laevis (African clawed frog)

YES1 Proteins for Rattus norvegicus (Rat)

YES1 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)



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