在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

WWTR1

WW domain-containing transcription regulator protein 1 is a protein in humans that is encoded by WWTR1 gene. Transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. WWTR1 enhances PAX8 and NKX2-1/TTF1-dependent gene activation. Regulates the nuclear accumulation of SMADS and has a key role in coupling them to the transcriptional machinery such as the mediator complex. Regulates embryonic stem-cell self-renewal, promotes cell proliferation and epithelial-mesenchymal transition.

WWTR1 Antibodies

WWTR1 for Homo sapiens (Human)

WWTR1 Proteins

WWTR1 Proteins for Mus musculus (Mouse)

WWTR1 Proteins for Homo sapiens (Human)



主站蜘蛛池模板: 亚洲精品无码国产片| 亚洲欧美另类久久久精品| 奇米影视777四色米奇影院| 亚洲国产精品一区第二页| 香蕉精品亚洲二区在线观看| 18禁勿入午夜网站入口| 成人无码av网站在线观看| 国产精品 精品国内自产拍| 欧美一区二区三区| 无码一区二区波多野结衣播放搜索 | 激情综合色综合啪啪五月丁香| 四川老熟女下面又黑又肥| 久久久久国色av免费看图片| 成人网站精品久久久久| 欧美人伦禁忌dvd放荡欲情| 中文字幕无码免费久久| 国产精品日本一区二区在线播放| 国产人妻高清国产拍精品| 国内芒果精品自线一区2021| 免费无码专区在线视频| 搡老女人老妇女老熟妇| 国产激情久久久久影院老熟女免费| 亚洲另类成人小说综合网| 国产美熟女乱又伦av果冻传媒| 亚洲精品久久久久午夜福禁果tⅴ| 日本一本二本三区免费 | 国产成人精品综合久久久| 无码人妻精品中文字幕| 中文天堂最新版在线www| 亚洲欧洲综合有码无码| 天天躁日日躁aaaaxxxx| 日韩精品一区二区在线观看| 亚洲色无码国产精品网站可下载| 97无码免费人妻超级碰碰碰碰| 18黄暴禁片在线观看| 青草青草久热精品视频在线观看 | 麻豆精品导航| 久久午夜夜伦鲁鲁片免费无码影视| 亚洲熟妇av一区二区三区浪潮| 精品久久久中文字幕人妻| 国产成人精品日本亚洲第一区|