在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

WWTR1

WW domain-containing transcription regulator protein 1 is a protein in humans that is encoded by WWTR1 gene. Transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. WWTR1 enhances PAX8 and NKX2-1/TTF1-dependent gene activation. Regulates the nuclear accumulation of SMADS and has a key role in coupling them to the transcriptional machinery such as the mediator complex. Regulates embryonic stem-cell self-renewal, promotes cell proliferation and epithelial-mesenchymal transition.

WWTR1 Antibodies

WWTR1 for Homo sapiens (Human)

WWTR1 Proteins

WWTR1 Proteins for Mus musculus (Mouse)

WWTR1 Proteins for Homo sapiens (Human)



主站蜘蛛池模板: 精品久久久无码人妻中文字幕| 999国内精品永久免费观看| 国产精品无码一区二区在线观一| 国产自偷自偷免费一区| 国产精品久久久久久久久岛| 成人爽a毛片免费看| 精品卡1卡2卡三卡免费网站| 国产精品宾馆在线精品酒店| 国产精品国产免费无码专区不卡| 亚洲精品无码av中文字幕电影网站 | av无码东京热亚洲男人的天堂| 亚洲天堂2017无码| 亚洲中文字幕乱码一区| 伊人久久大香线蕉av成人| 人妻在卧室被老板疯狂进入| 2020精品国产自在现线看| 成 人色 网 站 欧美大片在线观看| 青楼妓女禁脔道具调教sm| 国产人妻精品午夜福利免费| 亚洲va欧美va天堂v国产综合 | 久久青青草原精品国产app| 极品人妻少妇一区二区三区 | gv天堂gv无码男同在线观看| 337p人体粉嫩胞高清视频| 男女性潮高清免费网站| 夜夜天天噜狠狠爱2019| 40岁成熟女人牲交片20分钟| 色爱情人网站| 18禁黄污无遮挡无码网站| 成人奭片免费观看| 亚洲aⅴ天堂av天堂无码麻豆| 亚洲精品无码av黄瓜影视| 亚洲日韩国产中文其他| 夜夜躁很很躁日日躁麻豆| 99re热视频这里只精品| 曰本大码熟中文字幕| 中文字幕 亚洲精品 第1页| 国产精品久久久久久无毒不卡| 18禁无遮挡无码网站免费| 国产人妻xxxx精品hd| 我的性奴的肉玩具1一17心奴|