VPS37A
VPS37A,是一種屬于泛素連接酶E3泛素連接酶家族的成員,在細胞內自噬過程中發揮關鍵作用。該蛋白參與自噬體與溶酶體的結合,促進自噬體的成熟和降解過程。VPS37A蛋白的異常表達與多種疾病相關,如阿爾茨海默病、帕金森病和癌癥等。針對VPS37A蛋白的藥物研發主要集中在自噬抑制劑領域,旨在通過調節自噬過程來治療相關疾病。目前,已有一些自噬抑制劑進入臨床試驗階段,顯示出良好的治療效果。例如,一些小分子抑制劑能夠特異性地抑制VPS37A蛋白的活性,從而阻止自噬體的形成和降解,進而抑制腫瘤細胞的生長和擴散。此外,一些靶向VPS37A蛋白的抗體藥物也在研發中,有望為相關疾病的治療提供新的選擇。
熱銷產品
VPS37A Antibody (CSB-PA567081)
驗證數據

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA567081(VPS37A Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)

The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA567081(VPS37A Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)

Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human fetal liver tissue and hela cell, Primary antibody: CSB-PA567081(VPS37A Antibody) at dilution 1/200 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 15 seconds
VPS37A Antibodies
VPS37A for Homo sapiens (Human)
產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
---|---|---|---|
CSB-PA025906GA01HU | VPS37A Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA567081 | VPS37A Antibody | Human,Mouse | ELISA,WB,IHC |
CSB-PA256766 | VPS37A Antibody | Human,Mouse | ELISA,WB,IHC |
VPS37A Proteins
VPS37A Proteins for Homo sapiens (Human)
產品貨號 | 產品名稱 | 來源 |
---|---|---|
CSB-YP818779HU CSB-EP818779HU CSB-BP818779HU CSB-MP818779HU CSB-EP818779HU-B |
Recombinant Human Vacuolar protein sorting-associated protein 37A (VPS37A) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |