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TNFRSF10A

TNFRSF10A是一種與腫瘤壞死因子超家族相關(guān)的蛋白,其全名為腫瘤壞死因子受體超家族成員10A。該蛋白也被稱為TRAIL-R1、CD261、DR4和APO2。TNFRSF10A在細(xì)胞凋亡過(guò)程中扮演重要角色,能夠與TRAIL(腫瘤壞死因子相關(guān)凋亡誘導(dǎo)配體)結(jié)合,觸發(fā)細(xì)胞凋亡信號(hào)通路。它在多種疾病中發(fā)揮作用,如癌癥和自身免疫性疾病。目前,針對(duì)TNFRSF10A的藥物研發(fā)正在進(jìn)展中,包括開發(fā)能夠特異性結(jié)合并抑制該蛋白的抗體藥物,以用于治療相關(guān)疾病。

熱銷產(chǎn)品

TNFRSF10A Antibody (CSB-PA023964LA01HU)

驗(yàn)證數(shù)據(jù)

CSB-PA023964LA01HU

Western Blot
Positive WB detected in: HEK293 whole cell lysate
All lanes: TNFRSF10A antibody at 3.2μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 51 kDa
Observed band size: 51 kDa

CSB-PA023964LA01HU

IHC image of CSB-PA023964LA01HU diluted at 1:400 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

CSB-PA023964LA01HU

IHC image of CSB-PA023964LA01HU diluted at 1:400 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

CSB-PA023964LA01HU

Immunofluorescent analysis of A549 cells using CSB-PA023964LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

CSB-PA023964LA01HU

Immunoprecipitating TNFRSF10A in 293 whole cell lysate
Lane 1: Rabbit control IgG (1μg) instead of CSB-PA023964LA01HU in 293 whole cell lysate. For western blotting, a HRP-conjugated Protein G antibody was used as the secondary antibody (1/2000)
Lane 2: CSB-PA023964LA01HU (6μg) + 293 whole cell lysate (500μg)
Lane 3: 293 whole cell lysate (10μg)

TNFRSF10A Antibodies

TNFRSF10A for Homo sapiens (Human)

TNFRSF10A Proteins

TNFRSF10A Proteins for Homo sapiens (Human)



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