TLR5
TLR5，全稱為Toll樣受體5，是一種重要的模式識別受體。它主要在免疫細(xì)胞和上皮細(xì)胞上表達(dá)，能夠識別細(xì)菌鞭毛蛋白等病原體相關(guān)分子模式（PAMPs），并激活下游信號通路，引發(fā)免疫反應(yīng)。TLR5在免疫防御中扮演著關(guān)鍵角色，其異常表達(dá)與多種疾病相關(guān)，如肺癌、炎癥性腸病等。近年來，針對TLR5的藥物研發(fā)取得了一定進(jìn)展，有望用于治療相關(guān)疾病。例如，TLR5激動劑可增強(qiáng)疫苗免疫反應(yīng)，而TLR5拮抗劑則可能用于治療自身免疫性疾病。
熱銷產(chǎn)品
Recombinant Human Toll-like receptor 5 (TLR5), partial (CSB-EP023604HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
TLR5 Recombinant Monoclonal Antibody (CSB-RA545516A0HU)
驗(yàn)證數(shù)據(jù)
Western Blot
Positive WB detected in: THP-1 whole cell lysate, RAW264.7 whole cell lysate, U-251 whole cell lysate, K562 whole cell lysate
All lanes: TLR5 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 98 kDa
Observed band size: 98 kDa
TLR5 Antibodies
TLR5 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA023604GA01HU | TLR5 Antibody | Human,Mouse | ELISA,WB |
| CSB-PA218621 | TLR5 Antibody | Human | ELISA,IHC |
| CSB-PA296982 | TLR5 Antibody | Human | ELISA,IHC |
| CSB-PA023604LA01HU | TLR5 Antibody | Human, Mouse | ELISA, WB, IHC, IF |
| CSB-PA023604LB01HU | TLR5 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA023604LC01HU | TLR5 Antibody, FITC conjugated | Human | |
| CSB-PA023604LD01HU | TLR5 Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA545516A0HU | TLR5 Recombinant Monoclonal Antibody | Human | ELISA, WB |
TLR5 Proteins
TLR5 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP023604HU CSB-BP023604HU CSB-MP023604HU CSB-EP023604HU-B |
Recombinant Human Toll-like receptor 5 (TLR5), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP023604HU | Recombinant Human Toll-like receptor 5 (TLR5), partial | E.coli |
TLR5 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP023604MO CSB-EP023604MO CSB-BP023604MO CSB-MP023604MO CSB-EP023604MO-B |
Recombinant Mouse Toll-like receptor 5 (Tlr5), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
