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Your Good Partner in Biology Research

TH

Th,全稱為Tamm-Horsfall蛋白(THP),是一種由腎臟髓袢升支及遠(yuǎn)端小管曲部的上皮細(xì)胞合成分泌的糖蛋白。它也是尿液中含量最多的蛋白之一,常見別名包括T-H糖蛋白。在正常情況下,尿液中含有少量的THP,當(dāng)尿THP排出減少時,可能與腎實質(zhì)病變?nèi)缏阅I衰竭及急性腎小球腎炎等疾病有關(guān),這些疾病會導(dǎo)致腎單位大量減少,從而使GFR顯著降低。相反,尿液THP含量增加則可能與間質(zhì)性腎炎、尿路長期梗阻、自身免疫性藥物中毒、銅和鉻中毒等疾病引起的腎臟損傷有關(guān),且其含量變化與病情相一致。此外,THP在尿道結(jié)石患者體外震波碎石治療中,其含量變化也可用于治療效果的判斷。在藥物研發(fā)方面,雖然已有國外研究者報道了腎結(jié)石大鼠腎臟組織THP表達(dá)的結(jié)果,但治療因素干預(yù)下腎結(jié)石大鼠腎臟組織表達(dá)的研究尚未見報道,這為解析腎結(jié)石發(fā)病機(jī)理提供了新的研究方向。

熱銷產(chǎn)品

TH Antibody (CSB-PA023470LA01HU)

驗證數(shù)據(jù)

CSB-PA023470LA01HU

Western Blot
Positive WB detected in: A549 whole cell lysate, Hela whole cell lysate, Rat brain tissue, Rat liver tissue, Mouse liver tissue, Mouse brain tissue
All lanes: TH antibody at 4μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 59, 56, 57, 46, 45 kDa
Observed band size: 59 kDa

CSB-PA023470LA01HU

Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA023470LA01HU at dilution of 1:100

CSB-PA023470LA01HU

Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA023470LA01HU at dilution of 1:100

Human tyrosine hydroxylase,TH ELISA Kit (CSB-E09661h)

驗證數(shù)據(jù)

CSB-E09661h 標(biāo)準(zhǔn)曲線

貨號:CSB-E09661h

規(guī)格:96T/48T

靈敏度:0.078 ng/mL

檢測范圍:0.312 ng/mL-20 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

TH Antibodies

TH for Homo sapiens (Human)

TH for Rattus norvegicus (Rat)

TH Proteins

TH Proteins for Homo sapiens (Human)

TH ELISA Kit

TH ELISA Kit for Homo sapiens (Human)