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TFAM

Transcription factor A, mitochondrial is a protein in humans that is encoded by TFAM gene. Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA.

TFAM Antibodies

TFAM for Homo sapiens (Human)

TFAM Proteins

TFAM Proteins for Homo sapiens (Human)

TFAM Proteins for Mus musculus (Mouse)

TFAM Proteins for Rattus norvegicus (Rat)

TFAM Proteins for Bos taurus (Bovine)

TFAM Proteins for Trachypithecus cristatus (Silvered leaf-monkey) (Presbytis cristata)

TFAM Proteins for Sus scrofa (Pig)