在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SETD2

Histone methyltransferase that specifically trimethylates 'Lys-36' of histone H3 (H3K36me3) using dimethylated 'Lys-36' (H3K36me2) as substrate. It is capable of trimethylating unmethylated H3K36 (H3K36me0) in vitro. Represents the main enzyme generating H3K36me3, a specific tag for epigenetic transcriptional activation (By similarity). Plays a role in chromatin structure modulation during elongation by coordinating recruitment of the FACT complex and by interacting with hyperphosphorylated POLR2A. Acts as a key regulator of DNA mismatch repair in G1 and early S phase by generating H3K36me3, a mark required to recruit MSH6 subunit of the MutS alpha complex: early recruitment of the MutS alpha complex to chromatin to be replicated allows a quick identification of mismatch DNA to initiate the mismatch repair reaction. Required for DNA double-strand break repair in response to DNA damage: acts by mediating formation of H3K36me3, promoting recruitment of RAD51 and DNA repair via homologous recombination (HR). Acts as a tumor suppressor. H3K36me3 also plays an essential role in the maintenance of a heterochromatic state, by recruiting DNA methyltransferase DNMT3A.

SETD2 Antibodies

SETD2 for Homo sapiens (Human)

SETD2 Proteins

SETD2 Proteins for Homo sapiens (Human)



主站蜘蛛池模板: 亚洲人成手机电影网站| 国产嫖妓一区二区三区无码 | 精品久久人妻av中文字幕| 对白脏话肉麻粗话av| 亚洲国产成人av片在线播放| 新版天堂8中文在线最新版官网| 正在播放国产乱子伦最新视频| 欧美国产一区二区三区激情无套| 欧洲多毛裸体xxxxx| 国产人妻精品区一区二区三区 | 欧美做受视频播放| 国产裸体xxxx视频在线播放| 国产精品va在线播放| 欧美大屁股熟妇bbbbbb| 少妇扒开粉嫩小泬视频| 欧洲精品欧美精品| 日本伦奷在线播放| 亚洲精品成av人片天堂无码| 日本一卡二卡不卡视频查询| 蜜桃av久久久一区二区三区麻豆 | 伊在人天堂亚洲香蕉精品区| 99热成人精品国产免费| 国产精品成人av在线观看| 亚洲精品~无码抽插| 成人片黄网站a毛片免费观看 | 亚洲国产精品久久久久网站| 人妻体内射精一区二区三四| 国产又色又爽无遮挡免费动态图| 成人无码精品一区二区三区 | 成人无码视频| 真人抽搐一进一出gif| 一本色道久久东京热| 欧美精品色婷婷五月综合| 男人扒女人添高潮视频| 男男女女爽爽爽免费视频| 少妇极品熟妇人妻200片| 激情五月婷婷| 国产精品爆乳奶水无码视频免费| 久9视频这里只有精品试看| 中国女人高潮hd| 内射人妻视频国内|